Phosphodiesterase 4 inhibitor cilomilast inhibits fibroblast-mediated collagen gel degradation induced by tumor necrosis factor-alpha and neutrophil elastase.
about
PDE4 inhibitors as potential therapeutic agents in the treatment of COPD-focus on roflumilastPDE4 inhibitors: current statusPhosphodiesterase type 4 expression and anti-proliferative effects in human pulmonary artery smooth muscle cells.Effects of phosphodiesterase 4 inhibition on bleomycin-induced pulmonary fibrosis in mice.Cyclic nucleotide signalling in kidney fibrosis.The fibroblast-populated collagen matrix as a model of wound healing: a review of the evidence.Selective PDE4 inhibitors as potent anti-inflammatory drugs for the treatment of airway diseases.Reperfusion activates metalloproteinases that contribute to neurovascular injuryTreating COPD with PDE 4 inhibitors.Clinical and molecular genetics of the phosphodiesterases (PDEs).PDE4: a novel target in the treatment of chronic obstructive pulmonary disease.Cilomilast, an orally active phosphodiesterase 4 inhibitor for the treatment of COPD.Cytokine-dependent balance of mitogenic effects in primary human lung fibroblasts related to cyclic AMP signaling and phosphodiesterase 4 inhibition.Phosphodiesterase-4 inhibition augments human lung fibroblast vascular endothelial growth factor production induced by prostaglandin E2.PDE4 inhibitors roflumilast and rolipram augment PGE2 inhibition of TGF-{beta}1-stimulated fibroblasts.Expression of extracellular matrix metalloproteinase inducer glycosylation and caveolin-1 in healthy and inflamed human gingiva.Roflumilast fully prevents emphysema in mice chronically exposed to cigarette smoke.Roflumilast Ameliorates Airway Hyperresponsiveness Caused by Diet-Induced Obesity in a Murine Model.
P2860
Q24646836-DEC0E616-E994-4464-AFF2-8C858C957BB7Q24651926-F8EB39EC-E276-4EC2-A98B-BC7024A7389AQ25255769-98C98A3F-155A-408C-9750-EA7D7007690EQ33895012-9647D282-687B-4998-8ACD-A963787F2306Q35138860-D20CA247-84FE-4F16-99FB-57010AF1BF65Q35746718-51FD9BD1-4322-4E61-B38B-11576E6A210DQ36165890-DFEE3C8B-590B-414B-8B6B-A80B449BF49EQ36986393-4FF055DC-29CF-45E1-BC09-55DB0EAF4186Q37082594-6129F4FB-AB0A-480B-8AB9-E2DC68E48A47Q37657841-D95E21C4-6175-46B8-B173-96C8176BFF81Q37963175-95960685-9FBC-4B15-BBCF-60A3ECE11AB5Q43061572-307B0C03-4C27-40A8-901B-42E870057258Q43191327-DDA8FB10-D49E-45C6-A092-4CE2D4CB7FD5Q44614511-00160CBC-642A-461A-8E26-EB56CC8824E3Q46079226-1F55D4D9-D484-4FAB-AFC3-A29662B86E85Q46360418-3C68EC88-32E9-4362-89F9-AED33D792AEEQ46551607-46C78C22-C1A7-4036-B890-1A05001E67BDQ46612074-0333A206-FAD8-479D-BCC5-86187859CA06
P2860
Phosphodiesterase 4 inhibitor cilomilast inhibits fibroblast-mediated collagen gel degradation induced by tumor necrosis factor-alpha and neutrophil elastase.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Phosphodiesterase 4 inhibitor ...... alpha and neutrophil elastase.
@en
Phosphodiesterase 4 inhibitor ...... alpha and neutrophil elastase.
@nl
type
label
Phosphodiesterase 4 inhibitor ...... alpha and neutrophil elastase.
@en
Phosphodiesterase 4 inhibitor ...... alpha and neutrophil elastase.
@nl
prefLabel
Phosphodiesterase 4 inhibitor ...... alpha and neutrophil elastase.
@en
Phosphodiesterase 4 inhibitor ...... alpha and neutrophil elastase.
@nl
P2093
P2860
P356
P1476
Phosphodiesterase 4 inhibitor ...... alpha and neutrophil elastase.
@en
P2093
Fu-Qiang Wen
Hang Jun Wang
Qiuhong Fang
Stephen I Rennard
Tadashi Kohyama
Tetsu Kobayashi
Xiangde Liu
Yun Kui Zhu
P2860
P304
P356
10.1165/RCMB.4818
P577
2002-10-01T00:00:00Z