Alpha-conotoxins ImI and ImII. Similar alpha 7 nicotinic receptor antagonists act at different sites.
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Protein Folding Determinants: Structural Features Determining Alternative Disulfide Pairing in α- and χ/λ-Conotoxins † , ‡α-RgIA, a Novel Conotoxin That Blocks the α9α10 nAChR: Structure and Identification of Key Receptor-Binding ResiduesNMR Structure and Action on Nicotinic Acetylcholine Receptors of Water-soluble Domain of Human LYNX1Creating an 7 Nicotinic Acetylcholine Recognition Domain from the Acetylcholine-binding Protein: CRYSTALLOGRAPHIC AND LIGAND SELECTIVITY ANALYSESResidues Responsible for the Selectivity of α-Conotoxins for Ac-AChBP or nAChRsStructures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformationsTyrosine-rich conopeptides affect voltage-gated K+ channels.Conus peptides: biodiversity-based discovery and exogenomics.Alpha-conotoxins as pharmacological probes of nicotinic acetylcholine receptors.Bioactive marine drugs and marine biomaterials for brain diseasesAlpha-conotoxin AuIB isomers exhibit distinct inhibitory mechanisms and differential sensitivity to stoichiometry of alpha3beta4 nicotinic acetylcholine receptors.Chemical synthesis and characterization of two α4/7-conotoxinsAlanine scan of α-conotoxin RegIIA reveals a selective α3β4 nicotinic acetylcholine receptor antagonist.Snake and snail toxins acting on nicotinic acetylcholine receptors: fundamental aspects and medical applications.Physico-chemical characterization and synthesis of neuronally active alpha-conotoxins.Structure-activity relationships of alpha-conotoxins targeting neuronal nicotinic acetylcholine receptors.Computational approaches to understand alpha-conotoxin interactions at neuronal nicotinic receptors.Alpha-conotoxin OmIA is a potent ligand for the acetylcholine-binding protein as well as alpha3beta2 and alpha7 nicotinic acetylcholine receptors.alpha4/7-conotoxin Lp1.1 is a novel antagonist of neuronal nicotinic acetylcholine receptors.Structural determinates for apolipoprotein E-derived peptide interaction with the alpha7 nicotinic acetylcholine receptorSynthetic α-conotoxin mutants as probes for studying nicotinic acetylcholine receptors and in the development of novel drug leads.From toxins targeting ligand gated ion channels to therapeutic molecules.Design of new α-conotoxins: from computer modeling to synthesis of potent cholinergic compounds.Rational design of alpha-conotoxin analogues targeting alpha7 nicotinic acetylcholine receptors: improved antagonistic activity by incorporation of proline derivatives.Divergence of the Venom Exogene Repertoire in Two Sister Species of Turriconus.Nicotine inhibits potassium currents in Aplysia bag cell neurons.Alpha-conotoxins EpI and AuIB switch subtype selectivity and activity in native versus recombinant nicotinic acetylcholine receptors.Alpha-conotoxin BuIA, a novel peptide from Conus bullatus, distinguishes among neuronal nicotinic acetylcholine receptors.Inhibition of neuronal nicotinic acetylcholine receptor subtypes by alpha-Conotoxin GID and analogues.Epimerization-free access to C-terminal cysteine peptide acids, carboxamides, secondary amides, and esters via complimentary strategies.Neuronal Nicotinic Acetylcholine Receptor Modulators from Cone Snails.
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P2860
Alpha-conotoxins ImI and ImII. Similar alpha 7 nicotinic receptor antagonists act at different sites.
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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name
Alpha-conotoxins ImI and ImII. ...... onists act at different sites.
@en
Alpha-conotoxins ImI and ImII. ...... onists act at different sites.
@nl
type
label
Alpha-conotoxins ImI and ImII. ...... onists act at different sites.
@en
Alpha-conotoxins ImI and ImII. ...... onists act at different sites.
@nl
prefLabel
Alpha-conotoxins ImI and ImII. ...... onists act at different sites.
@en
Alpha-conotoxins ImI and ImII. ...... onists act at different sites.
@nl
P2093
P2860
P356
P1476
Alpha-conotoxins ImI and ImII. ...... onists act at different sites.
@en
P2093
Baldomero M Olivera
J Michael McIntosh
Michael Ellison
P2860
P304
P356
10.1074/JBC.M204565200
P407
P577
2002-10-15T00:00:00Z