Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions.
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Dopamine transporter cell surface localization facilitated by a direct interaction with the dopamine D2 receptorA thermodynamic ligand binding study of the third PDZ domain (PDZ3) from the mammalian neuronal protein PSD-95Human embryonic stem cell-derived neurons as a tool for studying neuroprotection and neurodegenerationBeta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signallingPDZ domains and their binding partners: structure, specificity, and modificationTraumatic brain injury: can the consequences be stopped?Applications and Challenges for Use of Cell-Penetrating Peptides as Delivery Vectors for Peptide and Protein CargosImaging of prehospital stroke therapeuticsα7 nicotinic ACh receptors as a ligand-gated source of Ca(2+) ions: the search for a Ca(2+) optimumNeuroprotection for stroke: current status and future perspectivesCurrent understanding of TRPM7 pharmacology and drug development for strokeThe role of nitric oxide in pre-synaptic plasticity and homeostasisThe NMDA receptor complex: a multifunctional machine at the glutamatergic synapseOptogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and impair memoryDisrupting GluA2-GAPDH Interaction Affects Axon and Dendrite DevelopmentBiomimetic divalent ligands for the acute disruption of synaptic AMPAR stabilizationMechanism underlying selective regulation of G protein-gated inwardly rectifying potassium channels by the psychostimulant-sensitive sorting nexin 27A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damageProtein grafting of p53TAD onto a leucine zipper scaffold generates a potent HDM dual inhibitorTonic GABAA Receptors as Potential Target for the Treatment of Temporal Lobe Epilepsy.Role of NMDA Receptor-Mediated Glutamatergic Signaling in Chronic and Acute NeuropathologiesTherapeutic use of PDZ protein-protein interaction antagonismDisruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuseInhibition of N-Methyl-D-aspartate-induced Retinal Neuronal Death by Polyarginine Peptides Is Linked to the Attenuation of Stress-induced Hyperpolarization of the Inner Mitochondrial Membrane PotentialSynaptic neurotransmission depression in ventral tegmental dopamine neurons and cannabinoid-associated addictive learningDAPK1 interaction with NMDA receptor NR2B subunits mediates brain damage in strokeKey role of tissue plasminogen activator in neurovascular couplingAn in silico analysis of the binding modes and binding affinities of small molecule modulators of PDZ-peptide interactionsTargeting protein-protein interactions with trimeric ligands: high affinity inhibitors of the MAGUK protein familySchizophrenia, amphetamine-induced sensitized state and acute amphetamine exposure all show a common alteration: increased dopamine D2 receptor dimerizationExtrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEPCaMKIIalpha interacts with M4 muscarinic receptors to control receptor and psychomotor functionStress- and mitogen-induced phosphorylation of the synapse-associated protein SAP90/PSD-95 by activation of SAPK3/p38gamma and ERK1/ERK2Physical interaction between the serotonin transporter and neuronal nitric oxide synthase underlies reciprocal modulation of their activityGlycine induces bidirectional modifications in N-methyl-D-aspartate receptor-mediated synaptic responses in hippocampal CA1 neuronsIntracellular protein interaction mapping with FRET hybrids.PDZ domain proteins: plug and play!Temporal dynamics of glyoxalase 1 in secondary neuronal injuryAccidental interaction between PDZ domains and diclofenac revealed by NMR-assisted virtual screening.Cell Permeable Peptides: A Promising Tool to Deliver Neuroprotective Agents in the Brain.
P2860
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P2860
Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Treatment of ischemic brain da ...... - PSD-95 protein interactions.
@en
Treatment of ischemic brain da ...... - PSD-95 protein interactions.
@nl
type
label
Treatment of ischemic brain da ...... - PSD-95 protein interactions.
@en
Treatment of ischemic brain da ...... - PSD-95 protein interactions.
@nl
prefLabel
Treatment of ischemic brain da ...... - PSD-95 protein interactions.
@en
Treatment of ischemic brain da ...... - PSD-95 protein interactions.
@nl
P2093
P356
P1433
P1476
Treatment of ischemic brain da ...... - PSD-95 protein interactions.
@en
P2093
James W Gurd
Lidong Liu
Mark Arundine
Michael Tymianski
Michael W Salter
Michelle Aarts
Shintaro Besshoh
P304
P356
10.1126/SCIENCE.1072873
P407
P50
P577
2002-10-01T00:00:00Z