Loss of p53 in enterocytes generates an inflammatory microenvironment enabling invasion and lymph node metastasis of carcinogen-induced colorectal tumors.
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Cytokine-Induced Modulation of Colorectal CancerMammalian models of chemically induced primary malignancies exploitable for imaging-based preclinical theragnostic researchMouse models of intestinal cancerChronic inflammation and the development of malignancy in the GI tractThe gastrointestinal tumor microenvironmentIKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis.Immunomodulatory Function of the Tumor Suppressor p53 in Host Immune Response and the Tumor Microenvironmentp53-dependent expression of CXCR5 chemokine receptor in MCF-7 breast cancer cellsInflammation and skeletal metastasisAn extra copy of p53 suppresses development of spontaneous Kras-driven but not radiation-induced cancerThe tumour suppressor CYLD regulates the p53 DNA damage responsePseudo-HE images derived from CARS/TPEF/SHG multimodal imaging in combination with Raman-spectroscopy as a pathological screening toolInput of microenvironmental regulation on colorectal cancer: role of the CCN family.Alantolactone, a natural sesquiterpene lactone, has potent antitumor activity against glioblastoma by targeting IKKβ kinase activity and interrupting NF-κB/COX-2-mediated signaling cascades.Downregulation of miR-193a-5p correlates with lymph node metastasis and poor prognosis in colorectal cancerRoles of tumor suppressors in regulating tumor-associated inflammation.Deletion of glutathione peroxidase-2 inhibits azoxymethane-induced colon cancer development.Apoptosis, autophagy, necroptosis, and cancer metastasisWild type p53 reactivation: from lab bench to clinic.Epithelial NAIPs protect against colonic tumorigenesis.Non-invasive assessment of the efficacy of new therapeutics for intestinal pathologies using serial endoscopic imaging of live miceShenling Baizhu San supresses colitis associated colorectal cancer through inhibition of epithelial-mesenchymal transition and myeloid-derived suppressor infiltrationConfocal laser endomicroscopy to monitor the colonic mucosa of mice.LIN28 cooperates with WNT signaling to drive invasive intestinal and colorectal adenocarcinoma in mice and humans.Primed for cancer: Li Fraumeni Syndrome and the pre-cancerous nichep53 amplifies Toll-like receptor 5 response in human primary and cancer cells through interaction with multiple signal transduction pathwaysInactivation of the retinoblastoma gene yields a mouse model of malignant colorectal cancerTargeted Deletion of p53 in Lgr5-Expressing Intestinal Stem Cells Promotes Colon Tumorigenesis in a Preclinical Model of Colitis-Associated Cancer.Prognostic impact of c-Rel nuclear expression and REL amplification and crosstalk between c-Rel and the p53 pathway in diffuse large B-cell lymphoma.Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer.Protective role of p53 in skin cancer: Carcinogenesis studies in mice lacking epidermal p53.EI24 regulates epithelial-to-mesenchymal transition and tumor progression by suppressing TRAF2-mediated NF-κB activity.Rapidly cycling Lgr5+ stem cells are exquisitely sensitive to extrinsic dietary factors that modulate colon cancer risk.Antidepressant fluoxetine and its potential against colon tumors.Deficiency in p53 is required for doxorubicin induced transcriptional activation of NF-кB target genes in human breast cancerIL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis.Ubiquitin-like (UBX)-domain-containing protein, UBXN2A, promotes cell death by interfering with the p53-Mortalin interactions in colon cancer cellsOrigins of metastatic traits.NF-κB in colorectal cancer.Noninvasive fluorescence imaging of small animals.
P2860
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P2860
Loss of p53 in enterocytes generates an inflammatory microenvironment enabling invasion and lymph node metastasis of carcinogen-induced colorectal tumors.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh-hant
name
Loss of p53 in enterocytes gen ...... gen-induced colorectal tumors.
@en
Loss of p53 in enterocytes gen ...... gen-induced colorectal tumors.
@nl
type
label
Loss of p53 in enterocytes gen ...... gen-induced colorectal tumors.
@en
Loss of p53 in enterocytes gen ...... gen-induced colorectal tumors.
@nl
prefLabel
Loss of p53 in enterocytes gen ...... gen-induced colorectal tumors.
@en
Loss of p53 in enterocytes gen ...... gen-induced colorectal tumors.
@nl
P2093
P50
P1433
P1476
Loss of p53 in enterocytes gen ...... gen-induced colorectal tumors.
@en
P2093
Alexander Meining
André Lechel
David Horst
Franz G Bader
Irina Kerle
Julia Slotta-Huspenina
Markus F Neurath
Olivia Prazeres da Costa
Paul K Ziegler
Sarah Schwitalla
P304
P356
10.1016/J.CCR.2012.11.014
P577
2012-12-27T00:00:00Z