Cholesterol is necessary both for the toxic effect of Abeta peptides on vascular smooth muscle cells and for Abeta binding to vascular smooth muscle cell membranes.
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The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptideCholesterol balance in prion diseases and Alzheimer's diseasePathophysiologic relationship between Alzheimer's disease, cerebrovascular disease, and cardiovascular risk: A review and synthesisBiophysical insights into how surfaces, including lipid membranes, modulate protein aggregation related to neurodegeneration.Ultrafast propagation of β-amyloid fibrils in oligomeric cloud.TRPM8 and Nav1.8 sodium channels are required for transthyretin-induced calcium influx in growth cones of small-diameter TrkA-positive sensory neurons.Amyloidogenic and non-amyloidogenic transthyretin variants interact differently with human cardiomyocytes: insights into early events of non-fibrillar tissue damage.Alpha-ketoglutarate dehydrogenase complex-dependent succinylation of proteins in neurons and neuronal cell lines.Alterations in Lipid Levels of Mitochondrial Membranes Induced by Amyloid-β: A Protective Role of Melatonin.The involvement of lipid rafts in Alzheimer's disease.Biosensor-based label-free assays of amyloid growth.Oxidative stress and cell membranes in the pathogenesis of Alzheimer's disease.Membrane and surface interactions of Alzheimer's Aβ peptide--insights into the mechanism of cytotoxicity.Neurodegeneration in familial amyloidotic polyneuropathy.Molecular Anti-inflammatory Mechanisms of Retinoids and Carotenoids in Alzheimer's Disease: a Review of Current Evidence.The beta-amyloid protein of Alzheimer's disease binds to membrane lipids but does not bind to the alpha7 nicotinic acetylcholine receptor.Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide.Retardation of Abeta fibril formation by phospholipid vesicles depends on membrane phase behavior.Increased membrane cholesterol might render mature hippocampal neurons more susceptible to beta-amyloid-induced calpain activation and tau toxicity.AβP1-42 incorporation and channel formation in planar lipid membranes: the role of cholesterol and its oxidation products.Glycosphingolipid-facilitated membrane insertion and internalization of cobra cardiotoxin. The sulfatide.cardiotoxin complex structure in a membrane-like environment suggests a lipid-dependent cell-penetrating mechanism for membrane binding polypeptDysregulation of Ca2+ homeostasis in Alzheimer's disease: role in acetylcholinesterase production and AMPA receptor internalization.The beta-amyloid peptide of Alzheimer's disease decreases adhesion of vascular smooth muscle cells to the basement membrane.Aβ42 oligomers, but not fibrils, simultaneously bind to and cause damage to ganglioside-containing lipid membranes.Copper-mediated amyloid-beta toxicity is associated with an intermolecular histidine bridge.
P2860
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P2860
Cholesterol is necessary both for the toxic effect of Abeta peptides on vascular smooth muscle cells and for Abeta binding to vascular smooth muscle cell membranes.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
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2003年學術文章
@zh-hant
name
Cholesterol is necessary both ...... smooth muscle cell membranes.
@en
Cholesterol is necessary both ...... smooth muscle cell membranes.
@nl
type
label
Cholesterol is necessary both ...... smooth muscle cell membranes.
@en
Cholesterol is necessary both ...... smooth muscle cell membranes.
@nl
prefLabel
Cholesterol is necessary both ...... smooth muscle cell membranes.
@en
Cholesterol is necessary both ...... smooth muscle cell membranes.
@nl
P2093
P2860
P1476
Cholesterol is necessary both ...... smooth muscle cell membranes.
@en
P2093
Colin J Barrow
David H Small
Sharon Unabia
Su San Mok
Supundi Subasinghe
P2860
P304
P356
10.1046/J.1471-4159.2003.01552.X
P407
P577
2003-02-01T00:00:00Z