Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide. - Wikidata - awgldk - TriplyDB

Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide.

Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide.

http://www.wikidata.org/entity/Q40481988

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Copper excess, zinc deficiency, and cognition loss in Alzheimer's disease Expression of ATP binding cassette-transporter ABCG1 prevents cell death by transporting cytotoxic 7beta-hydroxycholesterol Oxysterols in the pathogenesis of major chronic diseases Insulin in the brain: its pathophysiological implications for States related with central insulin resistance, type 2 diabetes and Alzheimer's disease Oxidized cholesterol as the driving force behind the development of Alzheimer's disease Issues raised involving the copper hypotheses in the causation of Alzheimer's disease Loading into nanoparticles improves quercetin's efficacy in preventing neuroinflammation induced by oxysterols Male-specific association between a gamma-secretase polymorphism and premature coronary atherosclerosis.Metals and cholesterol: two sides of the same coin in Alzheimer's disease pathology.Alzheimer disease beta-amyloid activity mimics cholesterol oxidase.The risks of copper toxicity contributing to cognitive decline in the aging population and to Alzheimer's disease.Sterculic acid antagonizes 7-ketocholesterol-mediated inflammation and inhibits choroidal neovascularization.Biological activities of 7-dehydrocholesterol-derived oxysterols: implications for Smith-Lemli-Opitz syndrome Hydralazine modifies Aβ fibril formation and prevents modification by lipids in vitro.An internally controlled peripheral biomarker for Alzheimer's disease: Erk1 and Erk2 responses to the inflammatory signal bradykinin.Roles of cholesterol and lipids in the etiopathogenesis of Alzheimer's disease.Atherosclerosis and Alzheimer--diseases with a common cause? Inflammation, oxysterols, vasculature Micronutrients and Alzheimer's disease.The involvement of lipid rafts in Alzheimer's disease.Membrane-mediated amyloidogenesis and the promotion of oxidative lipid damage by amyloid beta proteins Promotion of oxidative lipid membrane damage by amyloid beta proteins Effects of amyloid beta-peptides on the lysis tension of lipid bilayer vesicles containing oxysterols.Links between copper and cholesterol in Alzheimer's disease.Oxysterols, cholesterol homeostasis, and Alzheimer disease.Environmental and dietary risk factors in Alzheimer's disease.Medical bioremediation of age-related diseases.Therapeutics for Alzheimer's disease based on the metal hypothesis Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis.Oxysterol-induced rearrangement of the liquid-ordered phase: a possible link to Alzheimer's disease?Paradoxical condensation of copper with elevated beta-amyloid in lipid rafts under cellular copper deficiency conditions: implications for Alzheimer disease Brain sterol dysregulation in sporadic AD and MCI: relationship to heme oxygenase-1.Membrane-targeted strategies for modulating APP and Abeta-mediated toxicity.Metal Dyshomeostasis and Their Pathological Role in Prion and Prion-Like Diseases: The Basis for a Nutritional Approach.Direct binding of cholesterol to the amyloid precursor protein: An important interaction in lipid-Alzheimer's disease relationships?Oxidative stress and cell membranes in the pathogenesis of Alzheimer's disease.The role of metallobiology and amyloid-β peptides in Alzheimer's disease.Road to Alzheimer's disease: the pathomechanism underlying.The link between altered cholesterol metabolism and Alzheimer's disease.Brain insulin dysregulation: implication for neurological and neuropsychiatric disorders.Plant polyphenols in the treatment of age-associated diseases: revealing the pleiotropic effects of icariin by network analysis.

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P2860

Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide.

http://www.wikidata.org/entity/Q40481988

description

2004 nî lūn-bûn

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2004年の論文

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年學術文章

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2004年學術文章

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2004年學術文章

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name

Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide.

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type

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Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide.

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Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide.

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Journal of Biological Chemistry

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Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide.

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Daniel L Alkon

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Thomas J Nelson

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P2860

Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis

Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-golgi network

Convergence of atherosclerosis and Alzheimer's disease: inflammation, cholesterol, and misfolded proteins

Alzheimer's disease: the cholesterol connection

Differential expression of cholesterol hydroxylases in Alzheimer's disease

Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice

Age-related cognitive deficits, impaired long-term potentiation and reduction in synaptic marker density in mice lacking the beta-amyloid precursor protein

Probing the origins of increased activity of the E22Q "Dutch" mutant Alzheimer's beta-amyloid peptide.

Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1.

A continuous fluorimetric assay for tumor necrosis factor-alpha converting enzyme.

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scholarly article

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10.1074/JBC.M409071200

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