Oligomerization of mu- and delta-opioid receptors. Generation of novel functional properties.
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Heterodimerization of alpha 2A- and beta 1-adrenergic receptorsCys-27 variant of human δ-opioid receptor modulates maturation and cell surface delivery of Phe-27 variant via heteromerizationA heterodimer-selective agonist shows in vivo relevance of G protein-coupled receptor dimers.Clinically employed opioid analgesics produce antinociception via μ-δ opioid receptor heteromers in Rhesus monkeysHeteromerization of G protein-coupled receptors: relevance to neurological disorders and neurotherapeutics.Standard opioid agonists activate heteromeric opioid receptors: evidence for morphine and [d-Ala(2)-MePhe(4)-Glyol(5)]enkephalin as selective μ-δ agonistsReceptor heteromerization and drug discovery.Allostery at G protein-coupled receptor homo- and heteromers: uncharted pharmacological landscapesUnidirectional cross-activation of GRPR by MOR1D uncouples itch and analgesia induced by opioidsMarked changes in signal transduction upon heteromerization of dopamine D1 and histamine H3 receptorsOpioid ligands with mixed mu/delta opioid receptor interactions: an emerging approach to novel analgesicsAntibodies to probe endogenous G protein-coupled receptor heteromer expression, regulation, and functionOpioid receptor heteromers in analgesiaCrystal structure of the µ-opioid receptor bound to a morphinan antagonistStructure of the δ-opioid receptor bound to naltrindoleSelective interactions between helix VIII of the human mu-opioid receptors and the C terminus of periplakin disrupt G protein activationHomo- and hetero-oligomerization of thyrotropin-releasing hormone (TRH) receptor subtypes. Differential regulation of beta-arrestins 1 and 2Dimerization and phosphorylation of thyrotropin-releasing hormone receptors are modulated by agonist stimulationMu and Delta opioid receptors activate the same G proteins in human neuroblastoma SH-SY5Y cellsOligomerization of opioid receptors with beta 2-adrenergic receptors: a role in trafficking and mitogen-activated protein kinase activationLigand-directed functional selectivity at the mu opioid receptor revealed by label-free integrative pharmacology on-targetCircadian-related heteromerization of adrenergic and dopamine D₄ receptors modulates melatonin synthesis and release in the pineal glandAnti-analgesic effect of the mu/delta opioid receptor heteromer revealed by ligand-biased antagonismCrosstalk between GABAB and mGlu1a receptors reveals new insight into GPCR signal integrationFormation of mu-/kappa-opioid receptor heterodimer is sex-dependent and mediates female-specific opioid analgesiaThe pseudo signal peptide of the corticotropin-releasing factor receptor type 2a decreases receptor expression and prevents Gi-mediated inhibition of adenylyl cyclase activityPharmacological Properties of Bivalent Ligands Containing Butorphan Linked to Nalbuphine, Naltrexone, and Naloxone at μ, δ, and κ Opioid ReceptorsFunctional characterization of G-protein-coupled receptors: a bioinformatics approach.A Role for the Distal Carboxyl Tails in Generating the Novel Pharmacology and G Protein Activation Profile of and Opioid Receptor Hetero-oligomersQuantitative codon optimisation of DNA libraries encoding sub-random peptides: design and characterisation of a novel library encoding transmembrane domain peptidesHomo- and heterodimerization of somatostatin receptor subtypes. Inactivation of sst(3) receptor function by heterodimerization with sst(2A).Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base.Delta opioid receptor on equine sperm cells: subcellular localization and involvement in sperm motility analyzed by computer assisted sperm analyzer (CASA).Direct interaction of GABAB receptors with M2 muscarinic receptors enhances muscarinic signaling.Search for the "ideal analgesic" in pain treatment by engineering the mu-opioid receptor.Contribution of mu and delta opioid receptors to the pharmacological profile of kappa opioid receptor subtypes.Diversifying the repertoire of G protein-coupled receptors through oligomerization.Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.Opioid-receptor-heteromer-specific trafficking and pharmacology.Delta-opioid receptor analgesia is independent of microglial activation in a rat model of neuropathic pain
P2860
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P2860
Oligomerization of mu- and delta-opioid receptors. Generation of novel functional properties.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh-hant
name
Oligomerization of mu- and del ...... f novel functional properties.
@en
Oligomerization of mu- and del ...... f novel functional properties.
@nl
type
label
Oligomerization of mu- and del ...... f novel functional properties.
@en
Oligomerization of mu- and del ...... f novel functional properties.
@nl
prefLabel
Oligomerization of mu- and del ...... f novel functional properties.
@en
Oligomerization of mu- and del ...... f novel functional properties.
@nl
P2093
P356
P1476
Oligomerization of mu- and del ...... f novel functional properties.
@en
P2093
Varghese G
P304
26128-26135
P356
10.1074/JBC.M000345200
P407
P577
2000-08-01T00:00:00Z