Reactions of manganese porphyrins with peroxynitrite and carbonate radical anion. - Wikidata - awgldk - TriplyDB

Reactions of manganese porphyrins with peroxynitrite and carbonate radical anion.

Reactions of manganese porphyrins with peroxynitrite and carbonate radical anion.

http://www.wikidata.org/entity/Q44406751

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SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathways Mn porphyrin-based SOD mimic, MnTnHex-2-PyP(5+), and non-SOD mimic, MnTBAP(3-), suppressed rat spinal cord ischemia/reperfusion injury via NF-κB pathways Metal-catalyzed protein tyrosine nitration in biological systems.Treatment with the catalytic metalloporphyrin AEOL 10150 reduces inflammation and oxidative stress due to inhalation of the sulfur mustard analog 2-chloroethyl ethyl sulfide.Supraspinal inactivation of mitochondrial superoxide dismutase is a source of peroxynitrite in the development of morphine antinociceptive tolerance.A peroxynitrite complex of copper: formation from a copper-nitrosyl complex, transformation to nitrite and exogenous phenol oxidative coupling or nitration.Superoxide dismutase mimics: chemistry, pharmacology, and therapeutic potential Long-term neuroprotection from a potent redox-modulating metalloporphyrin in the rat.Rational design of superoxide dismutase (SOD) mimics: the evaluation of the therapeutic potential of new cationic Mn porphyrins with linear and cyclic substituents.Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities.Manganese(III) complexes of bis(hydroxyphenyl)dipyrromethenes are potent orally active peroxynitrite scavengers.Oxidative stress and redox modulation potential in type 1 diabetes.Effect of lipophilicity of Mn (III) ortho N-alkylpyridyl- and diortho N, N'-diethylimidazolylporphyrins in two in-vitro models of oxygen and glucose deprivation-induced neuronal death.Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics An educational overview of the chemistry, biochemistry and therapeutic aspects of Mn porphyrins--From superoxide dismutation to H2O2-driven pathways.Long-term administration of a small molecular weight catalytic metalloporphyrin antioxidant, AEOL 10150, protects lungs from radiation-induced injury.Manganese porphyrin reduces renal injury and mitochondrial damage during ischemia/reperfusion.Mn porphyrin-based superoxide dismutase (SOD) mimic, MnIIITE-2-PyP5+, targets mouse heart mitochondria Strategies to decrease ongoing oxidant burden in chronic obstructive pulmonary disease.The metalloporphyrin antioxidant, MnTE-2-PyP, inhibits Th2 cell immune responses in an asthma model The antioxidant, MnTE-2-PyP, prevents side-effects incurred by prostate cancer irradiation.Anticancer therapeutic potential of Mn porphyrin/ascorbate system Bioavailability of metalloporphyrin-based SOD mimics is greatly influenced by a single charge residing on a Mn site Cytotoxic effects of Mn(III) N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate.Peroxynitrite formation in nitric oxide-exposed submitochondrial particles: detection, oxidative damage and catalytic removal by Mn-porphyrins.Electrochemical detection of peroxynitrite using hemin-PEDOT functionalized boron-doped diamond microelectrode A combination of two antioxidants (an SOD mimic and ascorbate) produces a pro-oxidative effect forcing Escherichia coli to adapt via induction of oxyR regulon.Oxidative stress and excitotoxicity: a therapeutic issue in multiple sclerosis?SOD-like activity of Mn(II) beta-octabromo-meso-tetrakis(N-methylpyridinium-3-yl)porphyrin equals that of the enzyme itself Pharmacokinetics of the potent redox-modulating manganese porphyrin, MnTE-2-PyP(5+), in plasma and major organs of B6C3F1 mice Early and late administration of MnTE-2-PyP5+ in mitigation and treatment of radiation-induced lung damage Impact of electrostatics in redox modulation of oxidative stress by Mn porphyrins: protection of SOD-deficient Escherichia coli via alternative mechanism where Mn porphyrin acts as a Mn carrier.Differential coordination demands in Fe versus Mn water-soluble cationic metalloporphyrins translate into remarkably different aqueous redox chemistry and biology.Lipophilicity is a critical parameter that dominates the efficacy of metalloporphyrins in blocking the development of morphine antinociceptive tolerance through peroxynitrite-mediated pathways.Comprehensive pharmacokinetic studies and oral bioavailability of two Mn porphyrin-based SOD mimics, MnTE-2-PyP5+ and MnTnHex-2-PyP5+.Peroxynitrite, a stealthy biological oxidant.Lipophilicity of potent porphyrin-based antioxidants: comparison of ortho and meta isomers of Mn(III) N-alkylpyridylporphyrins.The antioxidant mimetic, MnTE-2-PyP, reduces intracellular growth of Mycobacterium abscessus.Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy.Nitric oxide, oxidants, and protein tyrosine nitration.

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P2860

Reactions of manganese porphyrins with peroxynitrite and carbonate radical anion.

http://www.wikidata.org/entity/Q44406751

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年學術文章

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2003年學術文章

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name

Reactions of manganese porphyrins with peroxynitrite and carbonate radical anion.

@en

Reactions of manganese porphyrins with peroxynitrite and carbonate radical anion.

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type

label

Reactions of manganese porphyrins with peroxynitrite and carbonate radical anion.

@en

Reactions of manganese porphyrins with peroxynitrite and carbonate radical anion.

@nl

prefLabel

Reactions of manganese porphyrins with peroxynitrite and carbonate radical anion.

@en

Reactions of manganese porphyrins with peroxynitrite and carbonate radical anion.

@nl

P1433

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Journal of Biological Chemistry

P1476

Reactions of manganese porphyrins with peroxynitrite and carbonate radical anion.

@en

P2093

Dario Vitturi

http://www.w3.org/2001/XMLSchema#string

Gerardo Ferrer-Sueta

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Gidon Czapski

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Ines Batinic-Haberle

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Irwin Fridovich

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Rafael Radi

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Sara Goldstein

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P2860

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide

Unraveling peroxynitrite formation in biological systems.

Formation and properties of peroxynitrite as studied by laser flash photolysis, high-pressure stopped-flow technique, and pulse radiolysis.

Metalloporphyrin class of therapeutic catalytic antioxidants.

Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease.

Nitrogen dioxide and carbonate radical anion: two emerging radicals in biology.

H NMR and electronic absorption spectroscopy of paramagnetic water-soluble meso-tetraarylsubstituted cationic and anionic metalloporphyrins.

A metalloporphyrin-based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone.

Peroxynitrite-induced luminol chemiluminescence.

Bicarbonate enhances peroxidase activity of Cu,Zn-superoxide dismutase. Role of carbonate anion radical and scavenging of carbonate anion radical by metalloporphyrin antioxidant enzyme mimetics.

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27432-27438

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scholarly article

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10.1074/JBC.M213302200

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30

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278

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2003-04-16T00:00:00Z

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P698

12700236

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