Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis.
about
Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasisInterleukin-6 induces hepcidin expression through STAT3A time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosisN-glycosylation is important for the correct intracellular localization of HFE and its ability to decrease cell surface transferrin bindingAnemia of inflammation: the cytokine-hepcidin linkThe liver-specific microRNA miR-122 controls systemic iron homeostasis in miceER stress controls iron metabolism through induction of hepcidinPathophysiology of hereditary hemochromatosisModulation of bone morphogenetic protein signaling in vivo regulates systemic iron balanceImpact of HFE genetic testing on clinical presentation of hereditary hemochromatosis: new epidemiological dataLaboratory use of hepcidin in renal transplant recipientsRegulation of Iron Metabolism by Hepcidin under Conditions of InflammationPharmacology of iron transportMolecular basis of HFE-hemochromatosis.Iron regulation and the cell cycle: identification of an iron-responsive element in the 3'-untranslated region of human cell division cycle 14A mRNA by a refined microarray-based screening strategyEffects of strain and age on hepatic gene expression profiles in murine models of HFE-associated hereditary hemochromatosisA novel murine protein with no effect on iron homoeostasis is homologous with transferrin and is the putative inhibitor of carbonic anhydraseContribution of Hfe expression in macrophages to the regulation of hepatic hepcidin levels and iron loadingMenkes Copper ATPase (Atp7a) is a novel metal-responsive gene in rat duodenum, and immunoreactive protein is present on brush-border and basolateral membrane domainsGene chip analyses reveal differential genetic responses to iron deficiency in rat duodenum and jejunumEnhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasisDuodenal reductase activity and spleen iron stores are reduced and erythropoiesis is abnormal in Dcytb knockout mice exposed to hypoxic conditions.Global transcriptional response to Hfe deficiency and dietary iron overload in mouse liver and duodenumThe IronChip evaluation package: a package of perl modules for robust analysis of custom microarrays.A genome-wide association analysis of serum iron concentrationsStoichiometries of transferrin receptors 1 and 2 in human liverSystems analysis of iron metabolism: the network of iron pools and fluxesFerroportin1 is required for normal iron cycling in zebrafishPathophysiological consequences and benefits of HFE mutations: 20 years of research.Molecular mechanisms of hepcidin regulation: implications for the anemia of CKD.Living with iron (and oxygen): questions and answers about iron homeostasis.Duodenal absorption and tissue utilization of dietary heme and nonheme iron differ in rats.Gender-related variations in iron metabolism and liver diseases.Normal iron metabolism and the pathophysiology of iron overload disordersNew insights into the regulation of iron homeostasis.Hepcidin induction by transgenic overexpression of Hfe does not require the Hfe cytoplasmic tail, but does require hemojuvelin.Hepcidin--central regulator of iron metabolism.Of mice and men: the iron age.Interaction of the hereditary hemochromatosis protein HFE with transferrin receptor 2 is required for transferrin-induced hepcidin expression.Absorption of manganese and iron in a mouse model of hemochromatosis.
P2860
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P2860
Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Regulatory defects in liver an ...... sion in mouse hemochromatosis.
@en
Regulatory defects in liver an ...... sion in mouse hemochromatosis.
@nl
type
label
Regulatory defects in liver an ...... sion in mouse hemochromatosis.
@en
Regulatory defects in liver an ...... sion in mouse hemochromatosis.
@nl
prefLabel
Regulatory defects in liver an ...... sion in mouse hemochromatosis.
@en
Regulatory defects in liver an ...... sion in mouse hemochromatosis.
@nl
P2093
P356
P1433
P1476
Regulatory defects in liver an ...... sion in mouse hemochromatosis.
@en
P2093
Angel O Custodio
Belén Miñana
Cindy N Roy
Jos deGraaf
Lynne K Montross
Martina Muckenthaler
P2888
P304
P356
10.1038/NG1152
P407
P577
2003-05-01T00:00:00Z