E-proteins directly regulate expression of activation-induced deaminase in mature B cells. - Wikidata - awgldk - TriplyDB

E-proteins directly regulate expression of activation-induced deaminase in mature B cells.

E-proteins directly regulate expression of activation-induced deaminase in mature B cells.

http://www.wikidata.org/entity/Q44419402

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Activation-induced cytidine deaminase auto-activates and triggers aberrant gene expression Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathway Regulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombination HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase Cloning and functional characterisation of avian transcription factor E2A Stable long-term cultures of self-renewing B cells and their applications Regulation of Aicda expression and AID activity AID/APOBEC deaminases and cancer First AID (activation-induced cytidine deaminase) is needed to produce high affinity isotype-switched antibodies AID targeting: old mysteries and new challenges AID in aging and autoimmune diseases.A library of gene expression signatures to illuminate normal and pathological lymphoid biology.A tamoxifen inducible knock-in allele for investigation of E2A function.Functions and regulation of the APOBEC family of proteins Phenothiazine neuroleptics signal to the human insulin promoter as revealed by a novel high-throughput screen A coming-of-age story: activation-induced cytidine deaminase turns 10.B cell TLRs and induction of immunoglobulin class-switch DNA recombination.A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression Expression of activation-induced cytidine deaminase is regulated by cell division, providing a mechanistic basis for division-linked class switch recombination.3D trajectories adopted by coding and regulatory DNA elements: first-passage times for genomic interactions.A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate.The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia.Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair.AID and somatic hypermutation.Regulation of immunoglobulin gene transcription in a teleost fish: identification, expression and functional properties of E2A in the channel catfish.Histone deacetylase inhibitors upregulate B cell microRNAs that silence AID and Blimp-1 expression for epigenetic modulation of antibody and autoantibody responses.In vivo analysis of Aicda gene regulation: a critical balance between upstream enhancers and intronic silencers governs appropriate expression.Regulation of hypermutation by activation-induced cytidine deaminase phosphorylation Gene expression patterns define novel roles for E47 in cell cycle progression, cytokine-mediated signaling, and T lineage development The B lineage transcription factor E2A regulates apoptosis in chronic lymphocytic leukemia (CLL) cells.Protein phosphatase 2A (PP2A) is increased in old murine B cells and mediates p38 MAPK/tristetraprolin dephosphorylation and E47 mRNA instability.Aberrant expression of ID2, a suppressor of B-cell-specific gene expression, in Hodgkin's lymphoma.Aging impairs murine B cell differentiation and function in primary and secondary lymphoid tissues Aging murine B cells have decreased class switch induced by anti-CD40 or BAFF Immunosenescence and Challenges of Vaccination against Influenza in the Aging Population.Biochemical and phosphoproteomic analysis of the helix-loop-helix protein E47.MicroRNAs miR-155 and miR-16 Decrease AID and E47 in B Cells from Elderly Individuals

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E-proteins directly regulate expression of activation-induced deaminase in mature B cells.

http://www.wikidata.org/entity/Q44419402

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

@zh-my

2003年学术文章

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2003年學術文章

@yue

2003年學術文章

@zh-hant

name

E-proteins directly regulate e ...... d deaminase in mature B cells.

@en

E-proteins directly regulate e ...... d deaminase in mature B cells.

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type

label

E-proteins directly regulate e ...... d deaminase in mature B cells.

@en

E-proteins directly regulate e ...... d deaminase in mature B cells.

@nl

prefLabel

E-proteins directly regulate e ...... d deaminase in mature B cells.

@en

E-proteins directly regulate e ...... d deaminase in mature B cells.

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P1433

Nature Immunology

P1476

E-proteins directly regulate e ...... d deaminase in mature B cells.

@en

P2093

Camil Elie Sayegh

http://www.w3.org/2001/XMLSchema#string

Cornelis Murre

http://www.w3.org/2001/XMLSchema#string

Melanie W Quong

http://www.w3.org/2001/XMLSchema#string

Yasutoshi Agata

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P2860

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

Promotion of cell cycle progression by basic helix-loop-helix E2A

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

Histone-like TAFs within the PCAF histone acetylase complex

Internal IgH class switch region deletions are position-independent and enhanced by AID expression

Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms

A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation.

The ATM-related cofactor Tra1 is a component of the purified SAGA complex.

The CBP co-activator is a histone acetyltransferase

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586-593

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scholarly article

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10.1038/NI923

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6

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4

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2003-04-28T00:00:00Z

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10786006

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12717431

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