E-proteins directly regulate expression of activation-induced deaminase in mature B cells.
about
Activation-induced cytidine deaminase auto-activates and triggers aberrant gene expressionSimple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identitiesBCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathwayRegulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombinationHoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutationMicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocationMicroRNA-155 is a negative regulator of activation-induced cytidine deaminaseCloning and functional characterisation of avian transcription factor E2AStable long-term cultures of self-renewing B cells and their applicationsRegulation of Aicda expression and AID activityAID/APOBEC deaminases and cancerFirst AID (activation-induced cytidine deaminase) is needed to produce high affinity isotype-switched antibodiesAID targeting: old mysteries and new challengesAID in aging and autoimmune diseases.A library of gene expression signatures to illuminate normal and pathological lymphoid biology.A tamoxifen inducible knock-in allele for investigation of E2A function.Functions and regulation of the APOBEC family of proteinsPhenothiazine neuroleptics signal to the human insulin promoter as revealed by a novel high-throughput screenA coming-of-age story: activation-induced cytidine deaminase turns 10.B cell TLRs and induction of immunoglobulin class-switch DNA recombination.A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expressionExpression of activation-induced cytidine deaminase is regulated by cell division, providing a mechanistic basis for division-linked class switch recombination.3D trajectories adopted by coding and regulatory DNA elements: first-passage times for genomic interactions.A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate.The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia.Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair.AID and somatic hypermutation.Regulation of immunoglobulin gene transcription in a teleost fish: identification, expression and functional properties of E2A in the channel catfish.Histone deacetylase inhibitors upregulate B cell microRNAs that silence AID and Blimp-1 expression for epigenetic modulation of antibody and autoantibody responses.In vivo analysis of Aicda gene regulation: a critical balance between upstream enhancers and intronic silencers governs appropriate expression.Regulation of hypermutation by activation-induced cytidine deaminase phosphorylationGene expression patterns define novel roles for E47 in cell cycle progression, cytokine-mediated signaling, and T lineage developmentThe B lineage transcription factor E2A regulates apoptosis in chronic lymphocytic leukemia (CLL) cells.Protein phosphatase 2A (PP2A) is increased in old murine B cells and mediates p38 MAPK/tristetraprolin dephosphorylation and E47 mRNA instability.Aberrant expression of ID2, a suppressor of B-cell-specific gene expression, in Hodgkin's lymphoma.Aging impairs murine B cell differentiation and function in primary and secondary lymphoid tissuesAging murine B cells have decreased class switch induced by anti-CD40 or BAFFImmunosenescence and Challenges of Vaccination against Influenza in the Aging Population.Biochemical and phosphoproteomic analysis of the helix-loop-helix protein E47.MicroRNAs miR-155 and miR-16 Decrease AID and E47 in B Cells from Elderly Individuals
P2860
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P2860
E-proteins directly regulate expression of activation-induced deaminase in mature B cells.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
E-proteins directly regulate e ...... d deaminase in mature B cells.
@en
E-proteins directly regulate e ...... d deaminase in mature B cells.
@nl
type
label
E-proteins directly regulate e ...... d deaminase in mature B cells.
@en
E-proteins directly regulate e ...... d deaminase in mature B cells.
@nl
prefLabel
E-proteins directly regulate e ...... d deaminase in mature B cells.
@en
E-proteins directly regulate e ...... d deaminase in mature B cells.
@nl
P2093
P2860
P356
P1433
P1476
E-proteins directly regulate e ...... d deaminase in mature B cells.
@en
P2093
Camil Elie Sayegh
Cornelis Murre
Melanie W Quong
Yasutoshi Agata
P2860
P304
P356
10.1038/NI923
P407
P577
2003-04-28T00:00:00Z