Granzyme B in atherosclerosis and transplant vascular disease: association with cell death and atherosclerotic disease severity.
about
Perforin and granzyme B have separate and distinct roles during atherosclerotic plaque development in apolipoprotein E knockout miceGranzyme B degrades extracellular matrix and contributes to delayed wound closure in apolipoprotein E knockout micePerforin-independent extracellular granzyme B activity contributes to abdominal aortic aneurysmThe unmet need in the elderly: how immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccinesImmune-mediated vascular injury and dysfunction in transplant arteriosclerosisGranule exocytosis mediates immune surveillance of senescent cells.A20 Haploinsufficiency Aggravates Transplant Arteriosclerosis in Mouse Vascular Allografts: Implications for Clinical Transplantation.Spatial differences in the presence of FOXP3+ and GranzymeB+ T cells between the intra- and extravascular compartments in renal allograft vasculopathy.Cleavage of von Willebrand factor by granzyme M destroys its factor VIII binding capacity.Granzymes in age-related cardiovascular and pulmonary diseases.Intracellular versus extracellular granzyme B in immunity and disease: challenging the dogma.Granzymes and perforin in solid organ transplant rejection.Granzyme B-expressing neutrophils correlate with bacterial load in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques.Age-related changes in monocytes exacerbate neointimal hyperplasia after vascular injuryCD8+ T cell cytotoxicity mediates pathology in the skin by inflammasome activation and IL-1β production.The role of Granzyme B in atheromatous diseases.Plasma granzyme B in ST elevation myocardial infarction versus non-ST elevation acute coronary syndrome: comparisons with IL-18 and fractalkineThe possible role of granzyme B in the pathogenesis of chronic obstructive pulmonary disease.PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegenerationImmunosurveillance of senescent cells: the bright side of the senescence program.Blessing or curse? Proteomics in granzyme research.Perforin mediates endothelial cell death and resultant transplant vascular disease in cardiac allografts.Granzyme B is expressed in mouse mast cells in vivo and in vitro and causes delayed cell death independent of perforin.Design and characterization of a novel human Granzyme B inhibitor.Granzyme B-dependent proteolysis acts as a switch to enhance the proinflammatory activity of IL-1α.Granzyme B induces endothelial cell apoptosis and contributes to the development of transplant vascular disease.A possible role for CD8+ and non-CD8+ cell granzyme B in early small airway wall remodelling in centrilobular emphysema.Sinonasal T-cell expression of cytotoxic mediators granzyme B and perforin is reduced in patients with chronic rhinosinusitis.Granzyme B deficiency exacerbates lung inflammation in mice after acute lung injury.Antihemostatic Activity of Human Granzyme B Mediated by Cleavage of von Willebrand FactorAn Emerging Role for Serine Protease Inhibitors in T Lymphocyte Immunity and Beyond
P2860
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P2860
Granzyme B in atherosclerosis and transplant vascular disease: association with cell death and atherosclerotic disease severity.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Granzyme B in atherosclerosis ...... erosclerotic disease severity.
@en
Granzyme B in atherosclerosis ...... erosclerotic disease severity.
@nl
type
label
Granzyme B in atherosclerosis ...... erosclerotic disease severity.
@en
Granzyme B in atherosclerosis ...... erosclerotic disease severity.
@nl
prefLabel
Granzyme B in atherosclerosis ...... erosclerotic disease severity.
@en
Granzyme B in atherosclerosis ...... erosclerotic disease severity.
@nl
P2093
P1433
P1476
Granzyme B in atherosclerosis ...... erosclerotic disease severity.
@en
P2093
Agripina C Suarez
Bruce M McManus
David J Granville
Janet E Wilson
Jonathan C Choy
Paul C McDonald
Vivian H Y Hung
P304
P356
10.1097/01.MP.0000067424.12280.BC
P577
2003-05-01T00:00:00Z
P5875
P6179
1017911876