Comparative scoring of micronucleated reticulocytes in rat peripheral blood by flow cytometry and microscopy.
about
Comparison of in vitro and in vivo clastogenic potency based on benchmark dose analysis of flow cytometric micronucleus data.Integration of mutation and chromosomal damage endpoints into 28-day repeat dose toxicology studies.Evaluation of high-throughput screening for in vitro micronucleus test using fluorescence-based cell imaging.Pig-a mutation: kinetics in rat erythrocytes following exposure to five prototypical mutagens.Persistence of cisplatin-induced mutagenicity in hematopoietic stem cells: implications for secondary cancer risk following chemotherapyComparison of male versus female responses in the Pig-a mutation assay.Rat Pig-a mutation assay responds to the genotoxic carcinogen ethyl carbamate but not the non-genotoxic carcinogen methyl carbamate.Automated human blood micronucleated reticulocyte measurements for rapid assessment of chromosomal damageEfficient monitoring of in vivo pig-a gene mutation and chromosomal damage: summary of 7 published studies and results from 11 new reference compounds.Comparison of flow cytometry- and microscopy-based methods for measuring micronucleated reticulocyte frequencies in rodents treated with nongenotoxic and genotoxic chemicals.Gamma radiation at a human relevant low dose rate is genotoxic in mice.New and emerging technologies for genetic toxicity testing.How accurate is in vitro prediction of carcinogenicity?Genotoxic effects of high dose rate X-ray and low dose rate gamma radiation in Apc(Min/+) mice.In vivo pig-a and micronucleus study of the prototypical aneugen vinblastine sulfate.Evaluation of Short-term Myelotoxicity Study in Dietary Reduced Rats.Empirical analysis of BMD metrics in genetic toxicology part II: in vivo potency comparisons to promote reductions in the use of experimental animals for genetic toxicity assessment.Three-color labeling method for flow cytometric measurement of cytogenetic damage in rodent and human blood.Pig-a gene mutation and micronucleated reticulocyte induction in rats exposed to tumorigenic doses of the leukemogenic agents chlorambucil, thiotepa, melphalan, and 1,3-propane sultone.Spontaneous and mitomycin C-induced micronuclei in peripheral blood reticulocytes from severely malnourished rats.Interlaboratory validation of a CD71-based flow cytometric method (Microflow) for the scoring of micronucleated reticulocytes in mouse peripheral blood.International Pig-a gene mutation assay trial (stage III): results with N-methyl-N-nitrosourea.Mouse Pig-a and micronucleus assays respond to N-ethyl-N-nitrosourea, benzo[a]pyrene, and ethyl carbamate, but not pyrene or methyl carbamate.The rat gut micronucleus assay: a good choice for alternative in vivo genetic toxicology testing strategies.Flow cytometric method for scoring rat liver micronuclei with simultaneous assessments of hepatocyte proliferation.Assessment of 5-fluorouracil and 4-nitroquinoline-1-oxide in vivo genotoxicity with Pig-a mutation and micronucleus endpoints.Interlaboratory Pig-a gene mutation assay trial: Studies of 1,3-propane sultone with immunomagnetic enrichment of mutant erythrocytes.
P2860
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P2860
Comparative scoring of micronucleated reticulocytes in rat peripheral blood by flow cytometry and microscopy.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Comparative scoring of micronu ...... flow cytometry and microscopy.
@en
Comparative scoring of micronu ...... flow cytometry and microscopy.
@nl
type
label
Comparative scoring of micronu ...... flow cytometry and microscopy.
@en
Comparative scoring of micronu ...... flow cytometry and microscopy.
@nl
prefLabel
Comparative scoring of micronu ...... flow cytometry and microscopy.
@en
Comparative scoring of micronu ...... flow cytometry and microscopy.
@nl
P2093
P356
P1476
Comparative scoring of micronu ...... flow cytometry and microscopy.
@en
P2093
Carol R Tometsko
Dorothea K Torous
Francis G Murante
Nikki E Hall
Sarah E Gleason
Stephen D Dertinger
P304
P356
10.1093/TOXSCI/KFG143
P577
2003-05-28T00:00:00Z