Mutations E44D and V118I in the reverse transcriptase of HIV-1 play distinct mechanistic roles in dual resistance to AZT and 3TC.
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Structural basis of HIV-1 resistance to AZT by excisionN348I in the connection domain of HIV-1 reverse transcriptase confers zidovudine and nevirapine resistanceMeasuring enzymatic HIV-1 susceptibility to two reverse transcriptase inhibitors as a rapid and simple approach to HIV-1 drug-resistance testingNovel protease inhibitors (PIs) containing macrocyclic components and 3(R),3a(S),6a(R)-bis-tetrahydrofuranylurethane that are potent against multi-PI-resistant HIV-1 variants in vitro.The N348I mutation at the connection subdomain of HIV-1 reverse transcriptase decreases binding to nevirapine.Inhibition of HIV-1 reverse transcription: basic principles of drug action and resistance.HIV-1 drug resistance mutations: an updated framework for the second decade of HAARTAptamers that recognize drug-resistant HIV-1 reverse transcriptaseTargets for inhibition of HIV replication: entry, enzyme action, release and maturation.Structural Aspects of Drug Resistance and Inhibition of HIV-1 Reverse Transcriptase.Identification of a novel resistance (E40F) and compensatory (K43E) substitution in HIV-1 reverse transcriptase.Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine.The L74V mutation in human immunodeficiency virus type 1 reverse transcriptase counteracts enhanced excision of zidovudine monophosphate associated with thymidine analog resistance mutations.Gln(84) of moloney murine leukemia virus reverse transcriptase regulates the incorporation rates of ribonucleotides and deoxyribonucleotides.HIV Reverse Transcriptase and Protease Genes Variability Can Be a Biomarker Associated with HIV and Hepatitis B or C Coinfection.
P2860
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P2860
Mutations E44D and V118I in the reverse transcriptase of HIV-1 play distinct mechanistic roles in dual resistance to AZT and 3TC.
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
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name
Mutations E44D and V118I in th ...... ual resistance to AZT and 3TC.
@en
Mutations E44D and V118I in th ...... ual resistance to AZT and 3TC.
@nl
type
label
Mutations E44D and V118I in th ...... ual resistance to AZT and 3TC.
@en
Mutations E44D and V118I in th ...... ual resistance to AZT and 3TC.
@nl
prefLabel
Mutations E44D and V118I in th ...... ual resistance to AZT and 3TC.
@en
Mutations E44D and V118I in th ...... ual resistance to AZT and 3TC.
@nl
P2093
P2860
P356
P1476
Mutations E44D and V118I in th ...... ual resistance to AZT and 3TC.
@en
P2093
Bruno Marchand
Karidia Diallo
Matthias Götte
Mélanie Girouard
Suzanne McCormick
P2860
P304
34403-34410
P356
10.1074/JBC.M303528200
P407
P577
2003-06-20T00:00:00Z