Alpha4beta1 integrin affinity changes govern cell adhesion.
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How Natalizumab Binds and Antagonizes 4 IntegrinsBioactive hydrogel substrates: probing leukocyte receptor-ligand interactions in parallel plate flow chamber studiesA dry membrane protection technique to allow surface acoustic wave biosensor measurements of biological model membrane approaches.B-cell activation by membrane-bound antigens is facilitated by the interaction of VLA-4 with VCAM-1Genetic perturbation of the putative cytoplasmic membrane-proximal salt bridge aberrantly activates alpha(4) integrinsUVB-irradiation regulates VLA-4-mediated melanoma cell adhesion to endothelial VCAM-1 under flow conditions.Galphas-coupled receptor signaling actively down-regulates alpha4beta1-integrin affinity: a possible mechanism for cell de-adhesion.Discovery of very late antigen-4 (VLA-4, alpha4beta1 integrin) allosteric antagonists.Nitric oxide/cGMP pathway signaling actively down-regulates α4β1-integrin affinity: an unexpected mechanism for inducing cell de-adhesion.FRET detection of cellular alpha4-integrin conformational activation.Relationship between molecular and cellular dissociation rates for VLA-4/VCAM-1 interaction in the absence of shear stressMolecular basis for the dynamic strength of the integrin alpha4beta1/VCAM-1 interaction.Conformational mAb as a tool for integrin ligand discoveryReal-time analysis of the inside-out regulation of lymphocyte function-associated antigen-1 revealed similarities to and differences from very late antigen-4.Carbon monoxide down-regulates α4β1 integrin-specific ligand binding and cell adhesion: a possible mechanism for cell mobilization.Mobilization of hematopoietic stem and progenitor cells using inhibitors of CXCR4 and VLA-4.Therapeutic targeting and rapid mobilization of endosteal HSC using a small molecule integrin antagonist.Kindlin-3 Is Essential for the Resting α4β1 Integrin-mediated Firm Cell Adhesion under Shear Flow ConditionsVery late antigen-4 function of myeloblasts correlates with improved overall survival for patients with acute myeloid leukemia.Crosstalk between CXCR4/stromal derived factor-1 and VLA-4/VCAM-1 pathways regulates neutrophil retention in the bone marrow.Increased extracellular pressure enhances cancer cell integrin-binding affinity through phosphorylation of beta1-integrin at threonine 788/789Adhesion between human neutrophils and immobilized endothelial ligand vascular cell adhesion molecule 1: divalent ion effects.Overview: assays for studying integrin-dependent cell adhesion.Systems approach to phagocyte production and activation: neutrophils and monocytes.Real-time analysis of conformation-sensitive antibody binding provides new insights into integrin conformational regulation.Does aberrant membrane transport contribute to poor outcome in adult acute myeloid leukemia?A miniature Couette to generate shear for flow cytometry: studying real-time modulation of intracellular calcium in monocytic cells.Aspects of VLA-4 and LFA-1 regulation that may contribute to rolling and firm adhesion.Conformational regulation of alpha 4 beta 1-integrin affinity by reducing agents. "Inside-out" signaling is independent of and additive to reduction-regulated integrin activation.Real-time analysis of very late antigen-4 affinity modulation by shear.Leukocyte function-associated antigen 1-mediated adhesion stability is dynamically regulated through affinity and valency during bond formation with intercellular adhesion molecule-1.A new antihistamine levocetirizine inhibits eosinophil adhesion to vascular cell adhesion molecule-1 under flow conditions.Monocyte-derived tissue transglutaminase in multiple sclerosis patients: reflecting an anti-inflammatory status and function of the cells?Heparin II Domain of Fibronectin Uses α4β1 Integrin to Control Focal Adhesion and Stress Fiber Formation, Independent of Syndecan-4
P2860
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P2860
Alpha4beta1 integrin affinity changes govern cell adhesion.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Alpha4beta1 integrin affinity changes govern cell adhesion.
@en
Alpha4beta1 integrin affinity changes govern cell adhesion.
@nl
type
label
Alpha4beta1 integrin affinity changes govern cell adhesion.
@en
Alpha4beta1 integrin affinity changes govern cell adhesion.
@nl
prefLabel
Alpha4beta1 integrin affinity changes govern cell adhesion.
@en
Alpha4beta1 integrin affinity changes govern cell adhesion.
@nl
P2093
P2860
P356
P1476
Alpha4beta1 integrin affinity changes govern cell adhesion.
@en
P2093
Bruce S Edwards
Denise C Dwyer
Gordon Zwartz
Hisashi Tsuji
Larry A Sklar
Richard S Larson
Steven W Graves
Terry D Foutz
P2860
P304
38174-38182
P356
10.1074/JBC.M210472200
P407
P577
2003-07-03T00:00:00Z