Sphingosine-dependent protein kinase-1, directed to 14-3-3, is identified as the kinase domain of protein kinase C delta.
about
A house divided: ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell deathThe emerging role of FTY720 (Fingolimod) in cancer treatmentSerine 58 of 14-3-3zeta is a molecular switch regulating ASK1 and oxidant stress-induced cell deathExpression pattern of protein kinase Cδ during mouse embryogenesis.Re-configuration of sphingolipid metabolism by oncogenic transformation.Structural basis of protein kinase C isoform functionProtein modifications regulate the role of 14-3-3γ adaptor protein in cAMP-induced steroidogenesis in MA-10 Leydig cells.Phosphorylation of 14-3-3ζ at serine 58 and neurodegeneration following kainic acid-induced excitotoxicity.Protein kinase C {delta}-specific activity reporter reveals agonist-evoked nuclear activity controlled by Src family of kinases.Distinctive activation mechanisms and functions for protein kinase Cdelta.Destabilisation of dimeric 14-3-3 proteins as a novel approach to anti-cancer therapeutics.Sphingolipids: regulators of crosstalk between apoptosis and autophagyStructure and function of glycosphingolipids and sphingolipids: recollections and future trends14-3-3-regulated Ca(2+)-dependent protein kinase CPK3 is required for sphingolipid-induced cell death in Arabidopsis.Activation of brain protein phosphatase-1(I) following cardiac arrest and resuscitation involving an interaction with 14-3-3 gamma.Sphingosine-dependent apoptosis: a unified concept based on multiple mechanisms operating in concert.Caspases and kinases in a death grip.Oligomeric structure of 14-3-3 protein: what do we know about monomers?Oxidative stress and sarcomeric proteins.Sphingolipids in mitochondria.Sialyl-glycoconjugates in cholesterol-rich microdomains of P388 cells are the triggers for apoptosis induced by Rana catesbeiana oocyte ribonuclease.Sphingosine suppresses mesothelioma cell proliferation by inhibiting PKC-δ and inducing cell cycle arrest at the G(0)/G(1) phase.Sphingosine induces apoptosis in MKN-28 human gastric cancer cells in an SDK-dependent manner.Sphingosine 1-Phosphate Signaling as a Target in Hepatic Fibrosis Therapy.Convergent actions of I kappa B kinase beta and protein kinase C delta modulate mRNA stability through phosphorylation of 14-3-3 beta complexed with tristetraprolinSphingosine activates protein kinase A type II by a novel cAMP-independent mechanism.14-3-3 Proteins in Brain Development: Neurogenesis, Neuronal Migration and NeuromorphogenesisCeramide-induced apoptosis by translocation, phosphorylation, and activation of protein kinase Cdelta in the Golgi complex.Leader peptide-mediated transcriptional attenuation of lysine biosynthetic gene cluster in Thermus thermophilus.The sphingoid long chain base phytosphingosine activates AGC-type protein kinases in Saccharomyces cerevisiae including Ypk1, Ypk2, and Sch9.Essential requirement for sphingosine kinase 2 in a sphingolipid apoptosis pathway activated by FTY720 analogues.Sphingosine induces apoptosis in hippocampal neurons and astrocytes by activating caspase-3/-9 via a mitochondrial pathway linked to SDK/14-3-3 protein/Bax/cytochrome c.
P2860
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P2860
Sphingosine-dependent protein kinase-1, directed to 14-3-3, is identified as the kinase domain of protein kinase C delta.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
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2003年學術文章
@zh-hant
name
Sphingosine-dependent protein ...... ain of protein kinase C delta.
@en
Sphingosine-dependent protein ...... ain of protein kinase C delta.
@nl
type
label
Sphingosine-dependent protein ...... ain of protein kinase C delta.
@en
Sphingosine-dependent protein ...... ain of protein kinase C delta.
@nl
prefLabel
Sphingosine-dependent protein ...... ain of protein kinase C delta.
@en
Sphingosine-dependent protein ...... ain of protein kinase C delta.
@nl
P2093
P2860
P356
P1476
Sphingosine-dependent protein ...... ain of protein kinase C delta.
@en
P2093
Akikazu Hamaguchi
Donald A Withers
Erika Suzuki
Kazuhisa Iwabuchi
Kazuko Handa
Kimie Murayama
Senitiroh Hakomori
Shane C Masters
Toshiyuki Hikita
P2860
P304
41557-41565
P356
10.1074/JBC.M305294200
P407
P577
2003-07-10T00:00:00Z