Buffer kinetics shape the spatiotemporal patterns of IP3-evoked Ca2+ signals.
about
Bidirectional Ca²⁺ signaling occurs between the endoplasmic reticulum and acidic organellesIntracellular signaling by diffusion: can waves of hydrogen peroxide transmit intracellular information in plant cells?Recording single-channel activity of inositol trisphosphate receptors in intact cells with a microscope, not a patch clamp.Imaging the quantal substructure of single IP3R channel activity during Ca2+ puffs in intact mammalian cells.Simple data-driven models of intracellular calcium dynamics with predictive power.The influence of Ca²⁺ buffers on free [Ca²⁺] fluctuations and the effective volume of Ca²⁺ microdomains.Hindered cytoplasmic diffusion of inositol trisphosphate restricts its cellular range of action.Calcium domains around single and clustered IP3 receptors and their modulation by buffers.Superresolution localization of single functional IP3R channels utilizing Ca2+ flux as a readoutModulation of endoplasmic reticulum Ca2+ store filling by cyclic ADP-ribose promotes inositol trisphosphate (IP3)-evoked Ca2+ signals.Single-molecule tracking of inositol trisphosphate receptors reveals different motilities and distributionsTermination of Ca²+ release for clustered IP₃R channels.Stochastic simulations of pattern formation in excitable media.Comparative analysis of calcium spikes upon activation of serotonin(1A) and purinergic receptors.Modeling the statistics of elementary calcium release eventsInositol (1,4,5)-trisphosphate receptor microarchitecture shapes Ca2+ puff kineticsAnalysis of puff dynamics in oocytes: interdependence of puff amplitude and interpuff interval.Local subplasma membrane Ca2+ signals detected by a tethered Ca2+ sensor.Modulation of elementary calcium release mediates a transition from puffs to waves in an IP3R cluster model.Calcium waves in a grid of clustered channels with synchronous IP3 binding and unbinding.Distribution of inositol-1,4,5-trisphosphate receptor isotypes and ryanodine receptor isotypes during maturation of the rat hippocampusTemperature dependence of IP3-mediated local and global Ca2+ signals.Modeling Ca2+ feedback on a single inositol 1,4,5-trisphosphate receptor and its modulation by Ca2+ buffers.Cytosolic [Ca2+] regulation of InsP3-evoked puffs.Localization of puff sites adjacent to the plasma membrane: functional and spatial characterization of Ca2+ signaling in SH-SY5Y cells utilizing membrane-permeant caged IP3.cADPR stimulates SERCA activity in Xenopus oocytesMulti-dimensional resolution of elementary Ca2+ signals by simultaneous multi-focal imaging.Modeling of the modulation by buffers of Ca2+ release through clusters of IP3 receptorsShared functional defect in IP₃R-mediated calcium signaling in diverse monogenic autism syndromes.Targeting and clustering of IP3 receptors: key determinants of spatially organized Ca2+ signals.Measuring the kinetics of calcium binding proteins with flash photolysis.Dynamic clustering of IP3 receptors by IP3.Visualizing metal ions in cells: an overview of analytical techniques, approaches, and probes.Subplasma membrane Ca2+ signals.Calretinin: from a "simple" Ca(2+) buffer to a multifunctional protein implicated in many biological processes.Calcium is not required for triggering volume restoration in hypotonically challenged A549 epithelial cells.Do calcium buffers always slow down the propagation of calcium waves?Spindle function in Xenopus oocytes involves possible nanodomain calcium signaling.Ca(2+) puffs originate from preestablished stable clusters of inositol trisphosphate receptorsClustering of InsP3 receptors by InsP3 retunes their regulation by InsP3 and Ca2+.
P2860
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P2860
Buffer kinetics shape the spatiotemporal patterns of IP3-evoked Ca2+ signals.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Buffer kinetics shape the spatiotemporal patterns of IP3-evoked Ca2+ signals.
@en
Buffer kinetics shape the spatiotemporal patterns of IP3-evoked Ca2+ signals.
@nl
type
label
Buffer kinetics shape the spatiotemporal patterns of IP3-evoked Ca2+ signals.
@en
Buffer kinetics shape the spatiotemporal patterns of IP3-evoked Ca2+ signals.
@nl
prefLabel
Buffer kinetics shape the spatiotemporal patterns of IP3-evoked Ca2+ signals.
@en
Buffer kinetics shape the spatiotemporal patterns of IP3-evoked Ca2+ signals.
@nl
P2860
P1476
Buffer kinetics shape the spatiotemporal patterns of IP3-evoked Ca2+ signals.
@en
P2093
Ian Parker
Sheila L Dargan
P2860
P304
P356
10.1113/JPHYSIOL.2003.054247
P407
P577
2003-10-10T00:00:00Z