Prevention of bleomycin-induced lung fibrosis by aerosolization of heparin or urokinase in rabbits. - Wikidata - awgldk - TriplyDB

Prevention of bleomycin-induced lung fibrosis by aerosolization of heparin or urokinase in rabbits.

Prevention of bleomycin-induced lung fibrosis by aerosolization of heparin or urokinase in rabbits.

http://www.wikidata.org/entity/Q44673823

about

The Rho kinases: critical mediators of multiple profibrotic processes and rational targets for new therapies for pulmonary fibrosis Absence of proteinase-activated receptor-1 signaling affords protection from bleomycin-induced lung inflammation and fibrosis Alterations in cytoskeletal and immune function-related proteome profiles in whole rat lung following intratracheal instillation of heparin Pulmonary epithelium is a prominent source of proteinase-activated receptor-1-inducible CCL2 in pulmonary fibrosis.Urokinase-type plasminogen activator receptor (uPAR) ligation induces a raft-localized integrin signaling switch that mediates the hypermotile phenotype of fibrotic fibroblasts Uncoupling of the profibrotic and hemostatic effects of thrombin in lung fibrosis.Dabigatran, a direct thrombin inhibitor, demonstrates antifibrotic effects on lung fibroblasts.Role of the lysophospholipid mediators lysophosphatidic acid and sphingosine 1-phosphate in lung fibrosis.Prolonged exposure to sphingosine 1-phosphate receptor-1 agonists exacerbates vascular leak, fibrosis, and mortality after lung injury.Novel therapeutic approaches for pulmonary fibrosis.The quest for non-invasive delivery of bioactive macromolecules: a focus on heparins Urokinase and its receptors in chronic kidney disease.Proteolytic regulation of epithelial sodium channels by urokinase plasminogen activator: cutting edge and cleavage sites.Intratracheal Bleomycin Aerosolization: The Best Route of Administration for a Scalable and Homogeneous Pulmonary Fibrosis Rat Model?Tuberculosis, lung infections, interstitial lung disease, social issues and journalology in AJRCCM 2003.Cyclooxygenase-2 deficiency exacerbates bleomycin-induced lung dysfunction but not fibrosis Molecular and cellular mechanisms of pulmonary fibrosis.Pharmacologic therapies for idiopathic pulmonary fibrosis, past and future.PAI-1 promotes the accumulation of exudate macrophages and worsens pulmonary fibrosis following type II alveolar epithelial cell injury.Procoagulant signalling mechanisms in lung inflammation and fibrosis: novel opportunities for pharmacological intervention?A review of current and novel therapies for idiopathic pulmonary fibrosis Male sex hormones exacerbate lung function impairment after bleomycin-induced pulmonary fibrosis.A phase 1 trial of nebulised heparin in acute lung injury.The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis?Pleiotropic effects of heparin and heparinoids in peritoneal dialysis.Neither fibrin nor plasminogen activator inhibitor-1 deficiency protects lung function in a mouse model of acute lung injury Increased local expression of coagulation factor X contributes to the fibrotic response in human and murine lung injury.New perspectives in the treatment of idiopathic pulmonary fibrosis.Endoplasmic reticulum stress, a new wrestler, in the pathogenesis of idiopathic pulmonary fibrosis.A novel multi-network approach reveals tissue-specific cellular modulators of fibrosis in systemic sclerosis.The pathogenesis of idiopathic pulmonary fibrosis.Therapeutic modulation of coagulation and fibrinolysis in acute lung injury and the acute respiratory distress syndrome Coagulation cascade proteinases in lung injury and fibrosis.Sphingolipid regulation of tissue fibrosis TGF-β: Titan of Lung Fibrogenesis.Emerging therapeutic interventions for idiopathic pulmonary fibrosis.Advances in the treatment of idiopathic pulmonary fibrosis.Thrombin induces epithelial-mesenchymal transition via PAR-1, PKC, and ERK1/2 pathways in A549 cells.Efficacy of recombinant human soluble thrombomodulin for the treatment of acute exacerbation of idiopathic pulmonary fibrosis: a single arm, non-randomized prospective clinical trial.Raised protein levels and altered cellular expression of factor VII activating protease (FSAP) in the lungs of patients with acute respiratory distress syndrome (ARDS).

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Prevention of bleomycin-induced lung fibrosis by aerosolization of heparin or urokinase in rabbits.

http://www.wikidata.org/entity/Q44673823

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Prevention of bleomycin-induce ...... parin or urokinase in rabbits.

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Prevention of bleomycin-induce ...... parin or urokinase in rabbits.

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American Journal of Respiratory and Critical Care Medicine

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Prevention of bleomycin-induce ...... parin or urokinase in rabbits.

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Andreas Breithecker

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Andreas Günther

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Clemens Ruppert

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Karin Quanz

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Leander Ermert

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Monika Ermert

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Norbert Lübke

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Philipp Markart

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P2860

Pulmonary surfactant in health and human lung diseases: state of the art.

NHLBI Workshop Summary. Pharmacological therapy for idiopathic pulmonary fibrosis. Past, present, and future.

Transient gene transfer and expression of Smad7 prevents bleomycin-induced lung fibrosis in mice

Changes in procoagulant and fibrinolytic gene expression during bleomycin-induced lung injury in the mouse.

Bleomycin-induced pulmonary fibrosis in fibrinogen-null mice.

Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene.

Aerosols for systemic treatment.

Alveolitis and collapse in the pathogenesis of pulmonary fibrosis.

New strategies for treatment of pulmonary fibrosis.

A preliminary study of long-term treatment with interferon gamma-1b and low-dose prednisolone in patients with idiopathic pulmonary fibrosis.

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1358-1365

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10.1164/RCCM.2201082

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11

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168

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Friedrich Grimminger

Ralph T Schermuly

Norbert Weissmann

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2003-12-01T00:00:00Z

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8985490

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pulmonary fibrosis