Inter- and intra-octarepeat Cu(II) site geometries in the prion protein: implications in Cu(II) binding cooperativity and Cu(II)-mediated assemblies.
about
Structure of the Flexible Amino-Terminal Domain of Prion Protein Bound to a Sulfated GlycanPrion-derived copper-binding peptide fragments catalyze the generation of superoxide anion in the presence of aromatic monoaminesComparative analysis of the human and chicken prion protein copper binding regions at pH 6.5.ESEEM analysis of multi-histidine Cu(II)-coordination in model complexes, peptides, and amyloid-βEngineering metal ion coordination to regulate amyloid fibril assembly and toxicity.Copper and Zinc Interactions with Cellular Prion Proteins Change Solubility of Full-Length Glycosylated Isoforms and Induce the Occurrence of Heterogeneous PhenotypesPrP charge structure encodes interdomain interactionsCopper and the prion protein: methods, structures, function, and diseaseZinc modulates copper coordination mode in prion protein octa-repeat subdomains.Ligand binding promotes prion protein aggregation--role of the octapeptide repeatsIdentification of the copper(II) coordinating residues in the prion protein by metal-catalyzed oxidation mass spectrometry: evidence for multiple isomers at low copper(II) loadingsNew insights into metal interactions with the prion protein: EXAFS analysis and structure calculations of copper binding to a single octarepeat from the prion protein.A reassessment of copper(II) binding in the full-length prion proteinMolecular dynamics simulations of two tandem octarepeats from the mammalian prion protein: fully Cu2+-bound and metal-free forms.A first-principle calculation of the XANES spectrum of Cu(2+) in water.The octarepeat domain of the prion protein binds Cu(II) with three distinct coordination modes at pH 7.4.The low-density lipoprotein receptor-related protein 1 (LRP1) mediates the endocytosis of the cellular prion protein.Modeling the interplay of glycine protonation and multiple histidine binding of copper in the prion protein octarepeat subdomains.A re-investigation of copper coordination in the octa-repeats region of the prion protein.Identifying the minimal copper- and zinc-binding site sequence in amyloid-beta peptides.Photo-induced crosslinking of prion protein oligomers and prions.
P2860
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P2860
Inter- and intra-octarepeat Cu(II) site geometries in the prion protein: implications in Cu(II) binding cooperativity and Cu(II)-mediated assemblies.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
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2003年学术文章
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2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
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2003年學術文章
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name
Inter- and intra-octarepeat Cu
@nl
Inter- and intra-octarepeat Cu ...... nd Cu(II)-mediated assemblies.
@en
type
label
Inter- and intra-octarepeat Cu
@nl
Inter- and intra-octarepeat Cu ...... nd Cu(II)-mediated assemblies.
@en
prefLabel
Inter- and intra-octarepeat Cu
@nl
Inter- and intra-octarepeat Cu ...... nd Cu(II)-mediated assemblies.
@en
P2093
P2860
P50
P356
P1476
Inter- and intra-octarepeat Cu ...... nd Cu(II)-mediated assemblies.
@en
P2093
Cristina Potrich
Gianfranco Menestrina
Reinerio González-Iglesias
Wolfram Meyer-Klaucke
P2860
P304
11753-11759
P356
10.1074/JBC.M312860200
P407
P577
2003-12-31T00:00:00Z