AIB1/SRC-3 deficiency affects insulin-like growth factor I signaling pathway and suppresses v-Ha-ras-induced breast cancer initiation and progression in mice.
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Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1Identification of target genes in breast cancer cells directly regulated by the SRC-3/AIB1 coactivatorIdentification of SRC3/AIB1 as a Preferred Coactivator for Hormone-activated Androgen ReceptorSRC-3 has a role in cancer other than as a nuclear receptor coactivator.PELP1 overexpression in the mouse mammary gland results in the development of hyperplasia and carcinomaTargeting the PELP1-KDM1 axis as a potential therapeutic strategy for breast cancerSRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migrationTherapeutic targeting of PELP1 prevents ovarian cancer growth and metastasisScaffold attachment factor B1 functions in development, growth, and reproductionSYT-SSX1 (synovial sarcoma translocated) regulates PIASy ligase activity to cause overexpression of NCOA3 proteinThe cooperative function of nuclear receptor coactivator 1 (NCOA1) and NCOA3 in placental development and embryo survivalRegulation of SRC-3 intercompartmental dynamics by estrogen receptor and phosphorylation.Steroid receptor coactivator-3/AIB1 promotes cell migration and invasiveness through focal adhesion turnover and matrix metalloproteinase expressionKnockout of SRC-1 and SRC-3 in Mice Decreases Cardiomyocyte Proliferation and Causes a Noncompaction Cardiomyopathy PhenotypeA maximum Likelihood Approach to Analyzing Incomplete Longitudinal Data in Mammary Tumor Development Experiments with Mice.Impaired hematopoiesis and delayed thrombopoietic recovery following sublethal irradiation in SRC‑3 knockout mice.Isoform-specific degradation of PR-B by E6-AP is critical for normal mammary gland developmentGlobal characterization of transcriptional impact of the SRC-3 coregulatorNCOA1 Directly Targets M-CSF1 Expression to Promote Breast Cancer Metastasis.Reprogramming the posttranslational code of SRC-3 confers a switch in mammalian systems biology.Genetic ablation of the amplified-in-breast cancer 1 inhibits spontaneous prostate cancer progression in mice.Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) familyThe steroid receptor coactivator-1 regulates twist expression and promotes breast cancer metastasis.Rapid estrogen-induced phosphorylation of the SRC-3 coactivator occurs in an extranuclear complex containing estrogen receptorSteroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferationPeptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1).The role and regulation of the nuclear receptor co-activator AIB1 in breast cancer.Overexpression and gender-specific differences of SRC-3 (SRC-3/AIB1) immunoreactivity in human non-small cell lung cancer: an in vivo studyThe steroid receptor coactivator-3 is required for developing neuroendocrine tumor in the mouse prostateHER2 Signaling Drives DNA Anabolism and Proliferation through SRC-3 Phosphorylation and E2F1-Regulated GenesSRC-3 coactivator regulates cell resistance to cytotoxic stress via TRAF4-mediated p53 destabilization.Direct control of cell cycle gene expression by proto-oncogene product ACTR, and its autoregulation underlies its transforming activity.Steroid receptor coactivator-1 upregulates integrin α₅ expression to promote breast cancer cell adhesion and migrationThe potential role of estrogen receptors and the SRC family as targets for the treatment of breast cancer.Role of the nuclear receptor coactivator AIB1-Delta4 splice variant in the control of gene transcription.Signaling within a coactivator complex: methylation of SRC-3/AIB1 is a molecular switch for complex disassembly.Amplified in breast cancer 1 promotes colorectal cancer progression through enhancing notch signaling.Tamoxifen inhibits ER-negative breast cancer cell invasion and metastasis by accelerating Twist1 degradation.Steroid receptor coactivators 1, 2, and 3: critical regulators of nuclear receptor activity and steroid receptor modulator (SRM)-based cancer therapySmall molecule inhibition of the steroid receptor coactivators, SRC-3 and SRC-1.
P2860
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P2860
AIB1/SRC-3 deficiency affects insulin-like growth factor I signaling pathway and suppresses v-Ha-ras-induced breast cancer initiation and progression in mice.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
AIB1/SRC-3 deficiency affects ...... ation and progression in mice.
@en
AIB1/SRC-3 deficiency affects ...... ation and progression in mice.
@nl
type
label
AIB1/SRC-3 deficiency affects ...... ation and progression in mice.
@en
AIB1/SRC-3 deficiency affects ...... ation and progression in mice.
@nl
prefLabel
AIB1/SRC-3 deficiency affects ...... ation and progression in mice.
@en
AIB1/SRC-3 deficiency affects ...... ation and progression in mice.
@nl
P2093
P1433
P1476
AIB1/SRC-3 deficiency affects ...... ation and progression in mice.
@en
P2093
Adrian V Lee
Jianming Xu
Shao-Qing Kuang
P304
P356
10.1158/0008-5472.CAN-03-3745
P407
P577
2004-03-01T00:00:00Z