The Wnt-5a-derived hexapeptide Foxy-5 inhibits breast cancer metastasis in vivo by targeting cell motility.
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Wnt5a exhibits layer-specific expression in adult skin, is upregulated in psoriasis, and synergizes with type 1 interferonThe orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanomaCancer Stem Cells in Human Gastrointestinal CancerWNT-5A: signaling and functions in health and diseaseTargeting the Wnt pathways for therapiesSchisandrin B attenuates cancer invasion and metastasis via inhibiting epithelial-mesenchymal transitionElevated level of Wnt5a protein in localized prostate cancer tissue is associated with better outcomeWNT5A signaling impairs breast cancer cell migration and invasion via mechanisms independent of the epithelial-mesenchymal transitionEmphasizing the role of Wnt5a protein expression to predict favorable outcome after radical prostatectomy in patients with low-grade prostate cancerThe prognostic significance of Wnt-5a expression in primary breast cancer is extended to premenopausal women.Challenging role of Wnt5a and its signaling pathway in cancer metastasis (Review).Striking the target in Wnt-y conditions: intervening in Wnt signaling during cancer progressionBreast cancer-specific mutations in CK1epsilon inhibit Wnt/beta-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration.Dvl2-dependent activation of Daam1 and RhoA regulates Wnt5a-induced breast cancer cell migration.WNT5A inhibits metastasis and alters splicing of Cd44 in breast cancer cells.Wnt5a as an effector of TGFβ in mammary development and cancerWnt5a suppresses epithelial ovarian cancer by promoting cellular senescence.Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I.Decreased Wnt5a Expression is a Poor Prognostic Factor in Triple-Negative Breast Cancer.Wnt-5a-regulated miR-101b controls COX2 expression in hippocampal neuronsRETRACTED: Wnt-5a signaling restores tamoxifen sensitivity in estrogen receptor-negative breast cancer cells.Hear the Wnt Ror: how melanoma cells adjust to changes in Wnt.A t-butyloxycarbonyl-modified Wnt5a-derived hexapeptide functions as a potent antagonist of Wnt5a-dependent melanoma cell invasionThe opposing roles of Wnt-5a in cancerCancer stem cell targeting: are we there yet?Wnt5a promotes migration of human osteosarcoma cells by triggering a phosphatidylinositol-3 kinase/Akt signals.WNT5A-mediated β-catenin-independent signalling is a novel regulator of cancer cell metabolismWNT signaling in glioblastoma and therapeutic opportunities.Non-canonical WNT5A signaling up-regulates the expression of the tumor suppressor 15-PGDH and induces differentiation of colon cancer cells.Challenging chemoresistant metastatic colorectal cancer: therapeutic strategies from the clinic and from the laboratory.FOXP3 suppresses breast cancer metastasis through downregulation of CD44.Migration and invasion of oral squamous carcinoma cells is promoted by WNT5A, a regulator of cancer progression.WNT-5A triggers Cdc42 activation leading to an ERK1/2 dependent decrease in MMP9 activity and invasive migration of breast cancer cells.Wnt/beta-catenin pathway: modulating anticancer immune response.Translation of WNT developmental programs into stem cell replacement strategies for the treatment of Parkinson's disease.Targeting the Wnt Pathway in Cancer: A Review of Novel Therapeutics.Developing Cures: Targeting Ontogenesis in Cancer.Treatment with the WNT5A-mimicking peptide Foxy-5 effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model.Mediation of osteogenic differentiation of human mesenchymal stem cells on titanium surfaces by a Wnt-integrin feedback loop.Potential therapeutic targets of triple-negative breast cancer based on its intrinsic subtype.
P2860
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P2860
The Wnt-5a-derived hexapeptide Foxy-5 inhibits breast cancer metastasis in vivo by targeting cell motility.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
The Wnt-5a-derived hexapeptide ...... vo by targeting cell motility.
@en
The Wnt-5a-derived hexapeptide ...... vo by targeting cell motility.
@nl
type
label
The Wnt-5a-derived hexapeptide ...... vo by targeting cell motility.
@en
The Wnt-5a-derived hexapeptide ...... vo by targeting cell motility.
@nl
prefLabel
The Wnt-5a-derived hexapeptide ...... vo by targeting cell motility.
@en
The Wnt-5a-derived hexapeptide ...... vo by targeting cell motility.
@nl
P2093
P1476
The Wnt-5a-derived hexapeptide ...... vo by targeting cell motility.
@en
P2093
Annette Säfholm
Janna Dejmek
Jeanette Rosenkvist
Pirkko Härkönen
P304
P356
10.1158/1078-0432.CCR-08-0711
P407
P577
2008-10-01T00:00:00Z