Increased expression of the multidrug transporter P-glycoprotein in limbic brain regions after amygdala-kindled seizures in rats.
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Combined effects of epileptic seizure and phenobarbital induced overexpression of P-glycoprotein in brain of chemically kindled ratsBlood-brain barrier active efflux transporters: ATP-binding cassette gene family.Drug resistance in brain diseases and the role of drug efflux transporters.Celecoxib treatment restores pharmacosensitivity in a rat model of pharmacoresistant epilepsy.Drug resistance in epilepsy: putative neurobiologic and clinical mechanisms.Challenges and opportunities in the application of pharmacogenetics to antiepileptic drug therapy.Drug transporters in the epileptic brain.Dose-response assessment of tariquidar and elacridar and regional quantification of P-glycoprotein inhibition at the rat blood-brain barrier using (R)-[(11)C]verapamil PET.A novel positron emission tomography imaging protocol identifies seizure-induced regional overactivity of P-glycoprotein at the blood-brain barrierTransporter hypothesis of drug-resistant epilepsy: challenges for pharmacogenetic approaches.Causes and Consequences of Variability in Drug Transporter Activity in Pediatric Drug Therapy.P-glycoprotein alters blood-brain barrier penetration of antiepileptic drugs in rats with medically intractable epilepsy.Drug transporters are altered in brain, liver and kidney of rats with chronic epilepsy induced by lithium-pilocarpine.Multidrug resistance in epilepsy: rats with drug-resistant seizures exhibit enhanced brain expression of P-glycoprotein compared with rats with drug-responsive seizures.Immunohistochemical localization of P-glycoprotein in rat brain and detection of its increased expression by seizures are sensitive to fixation and staining variables.Calcium-channel blocker verapamil administration in prolonged and refractory status epilepticus.Expression of multidrug transporters MRP1, MRP2, and BCRP shortly after status epilepticus, during the latent period, and in chronic epileptic rats.Influence of lamotrigine and topiramate on MDR1 expression in difficult-to-treat temporal lobe epilepsy.Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats.Inhibition of the multidrug transporter P-glycoprotein improves seizure control in phenytoin-treated chronic epileptic rats.Lack of association between the C3435T polymorphism in the human multidrug resistance (MDR1) gene and response to antiepileptic drug treatment.Peripheral inflammatory hyperalgesia modulates morphine delivery to the brain: a role for P-glycoprotein
P2860
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P2860
Increased expression of the multidrug transporter P-glycoprotein in limbic brain regions after amygdala-kindled seizures in rats.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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name
Increased expression of the mu ...... dala-kindled seizures in rats.
@en
Increased expression of the mu ...... dala-kindled seizures in rats.
@nl
type
label
Increased expression of the mu ...... dala-kindled seizures in rats.
@en
Increased expression of the mu ...... dala-kindled seizures in rats.
@nl
prefLabel
Increased expression of the mu ...... dala-kindled seizures in rats.
@en
Increased expression of the mu ...... dala-kindled seizures in rats.
@nl
P1433
P1476
Increased expression of the mu ...... dala-kindled seizures in rats.
@en
P2093
Holger A Volk
Wolfgang Löscher
P356
10.1016/J.EPLEPSYRES.2003.12.009
P577
2004-01-01T00:00:00Z