Demethoxy-Q, an intermediate of coenzyme Q biosynthesis, fails to support respiration in Saccharomyces cerevisiae and lacks antioxidant activity.
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A regulated response to impaired respiration slows behavioral rates and increases lifespan in Caenorhabditis elegansThe phosphatase Ptc7 induces coenzyme Q biosynthesis by activating the hydroxylase Coq7 in yeast.The Saccharomyces cerevisiae COQ10 gene encodes a START domain protein required for function of coenzyme Q in respiration.Genetic evidence for a multi-subunit complex in coenzyme Q biosynthesis in yeast and the role of the Coq1 hexaprenyl diphosphate synthase.NQR1 controls lifespan by regulating the promotion of respiratory metabolism in yeast.Overexpression of the Coq8 kinase in Saccharomyces cerevisiae coq null mutants allows for accumulation of diagnostic intermediates of the coenzyme Q6 biosynthetic pathway.Functional characterization of human COQ4, a gene required for Coenzyme Q10 biosynthesis.Molecular characterization of the human COQ5 C-methyltransferase in coenzyme Q10 biosynthesis.Metformin improves healthspan and lifespan in mice.Uncoupling the pleiotropic phenotypes of clk-1 with tRNA missense suppressors in Caenorhabditis elegans.Complementation of Saccharomyces cerevisiae coq7 mutants by mitochondrial targeting of the Escherichia coli UbiF polypeptide: two functions of yeast Coq7 polypeptide in coenzyme Q biosynthesis.Hydroxylation of demethoxy-Q6 constitutes a control point in yeast coenzyme Q6 biosynthesis176th ENMC International Workshop: diagnosis and treatment of coenzyme Q₁₀ deficiencyEndogenous synthesis of coenzyme Q in eukaryotes.CLD1 Reverses the Ubiquinone Insufficiency of Mutant cat5/coq7 in a Saccharomyces cerevisiae Model System.Coenzyme Q supplementation or over-expression of the yeast Coq8 putative kinase stabilizes multi-subunit Coq polypeptide complexes in yeast coq null mutants.Molecular genetics of ubiquinone biosynthesis in animals.Regulation of coenzyme Q biosynthesis in yeast: a new complex in the block.Invertebrate models for coenzyme q10 deficiency.Molecular diagnosis of coenzyme Q10 deficiency.The regulation of coenzyme q biosynthesis in eukaryotic cells: all that yeast can tell us.Mitochondrial respiration without ubiquinone biosynthesis.Balanced CoQ6 biosynthesis is required for lifespan and mitophagy in yeast.The role of DMQ(9) in the long-lived mutant clk-1.The effect of different ubiquinones on lifespan in Caenorhabditis elegans.Coq10, a mitochondrial coenzyme Q binding protein, is required for proper respiration in Schizosaccharomyces pombe.Chromatin-remodeling SWI/SNF complex regulates coenzyme Q6 synthesis and a metabolic shift to respiration in yeast.Coq3 and Coq4 define a polypeptide complex in yeast mitochondria for the biosynthesis of coenzyme Q.Mitochondrial dysfunction leads to reduced chronological lifespan and increased apoptosis in yeast.Comparison of a coq7 deletion mutant with other respiration-defective mutants in fission yeast.RNA-binding proteins regulate cell respiration and coenzyme Q biosynthesis by post-transcriptional regulation of COQ7.Respiratory-induced coenzyme Q biosynthesis is regulated by a phosphorylation cycle of Cat5p/Coq7p.
P2860
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P2860
Demethoxy-Q, an intermediate of coenzyme Q biosynthesis, fails to support respiration in Saccharomyces cerevisiae and lacks antioxidant activity.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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@zh-hans
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name
Demethoxy-Q, an intermediate o ...... nd lacks antioxidant activity.
@en
Demethoxy-Q, an intermediate o ...... nd lacks antioxidant activity.
@nl
type
label
Demethoxy-Q, an intermediate o ...... nd lacks antioxidant activity.
@en
Demethoxy-Q, an intermediate o ...... nd lacks antioxidant activity.
@nl
prefLabel
Demethoxy-Q, an intermediate o ...... nd lacks antioxidant activity.
@en
Demethoxy-Q, an intermediate o ...... nd lacks antioxidant activity.
@nl
P2093
P2860
P50
P356
P1476
Demethoxy-Q, an intermediate o ...... and lacks antioxidant activity
@en
P2093
Beth Marbois
Catherine F Clarke
María A Jiménez-Hidalgo
Plácido Navas
Sergio Padilla
Tanya Jonassen
P2860
P304
25995-26004
P356
10.1074/JBC.M400001200
P407
P577
2004-04-12T00:00:00Z