Identification of three key active site residues in the C-terminal domain of human recombinant folylpoly-gamma-glutamate synthetase by site-directed mutagenesis.
about
Mammalian mitochondrial and cytosolic folylpolyglutamate synthetase maintain the subcellular compartmentalization of folatesThe root indeterminacy-to-determinacy developmental switch is operated through a folate-dependent pathway in Arabidopsis thaliana.Resistance to antifolates.Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance.Molecular analysis of murine leukemia cell lines resistant to 5, 10-dideazatetrahydrofolate identifies several amino acids critical to the function of folylpolyglutamate synthetase.Effects of folylpolyglutamate synthetase modulation on chemosensitivity of colon cancer cells to 5-fluorouracil and methotrexate.
P2860
Identification of three key active site residues in the C-terminal domain of human recombinant folylpoly-gamma-glutamate synthetase by site-directed mutagenesis.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh-hant
name
Identification of three key ac ...... by site-directed mutagenesis.
@en
Identification of three key ac ...... by site-directed mutagenesis.
@nl
type
label
Identification of three key ac ...... by site-directed mutagenesis.
@en
Identification of three key ac ...... by site-directed mutagenesis.
@nl
prefLabel
Identification of three key ac ...... by site-directed mutagenesis.
@en
Identification of three key ac ...... by site-directed mutagenesis.
@nl
P2093
P2860
P356
P1476
Identification of three key ac ...... by site-directed mutagenesis.
@en
P2093
Sanghani PC
Sanghani SP
P2860
P304
27018-27027
P356
10.1074/JBC.274.38.27018
P407
P577
1999-09-01T00:00:00Z