Regulation of CXC chemokine receptor 4-mediated migration by the Tec family tyrosine kinase ITK.
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T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells.Selective expression rather than specific function of Txk and Itk regulate Th1 and Th2 responses.T-cell signaling regulated by the Tec family kinase, Itk.Differential roles of IL-2-inducible T cell kinase-mediated TCR signals in tissue-specific localization and maintenance of skin intraepithelial T cells.Characterisation of a K390R ITK kinase dead transgenic mouse--implications for ITK as a therapeutic target.The Galpha13-Rho signaling axis is required for SDF-1-induced migration through CXCR4.Itk signals promote neuroinflammation by regulating CD4+ T-cell activation and trafficking.Itk: the rheostat of the T cell response.IL2 Inducible T-cell Kinase, a Novel Therapeutic Target in MelanomaCutting edge: STAT6 signaling in eosinophils is necessary for development of allergic airway inflammation.Inhibition of CXCL12-mediated chemotaxis of Jurkat cells by direct immunotoxicants.Effects of SDF-1-CXCR4 signaling on microRNA expression and tumorigenesis in estrogen receptor-alpha (ER-α)-positive breast cancer cells.TEC-family kinases: regulators of T-helper-cell differentiation.Intracellular signalling controlling integrin activation in lymphocytes.A Small Molecule Inhibitor of ITK and RLK Impairs Th1 Differentiation and Prevents Colitis Disease Progression.Chemokine-dependent T cell migration requires aquaporin-3-mediated hydrogen peroxide uptakeSelective targeting of ITK blocks multiple steps of HIV replication.Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization.Regulation of T-cell migration and effector functions: insights from in vivo imaging studies.Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/TxkTEC and MAPK Kinase Signalling Pathways in T helper (TH) cell Development, TH2 Differentiation and Allergic Asthma.ITK inhibitors in inflammation and immune-mediated disorders.The role of Tec family kinases in the regulation of T-helper-cell differentiation.Transcriptome-based functional classifiers for direct immunotoxicity.Cytotoxicity of tumor antigen specific human T cells is unimpaired by arginine depletion.SLP-76 is required for optimal CXCR4-stimulated T lymphocyte firm arrest to ICAM-1 under shear flow.Differential sensitivity to Itk kinase signals for T helper 2 cytokine production and chemokine-mediated migrationSuccessful validation of genomic biomarkers for human immunotoxicity in Jurkat T cells in vitro.RhoA and RhoC are involved in stromal cell-derived factor-1-induced cell migration by regulating F-actin redistribution and assembly.Inherited Immunodeficiencies With High Predisposition to Epstein–Barr Virus-Driven Lymphoproliferative Diseases.Comparison of interleukin-2-inducible kinase (ITK) inhibitors and potential for combination therapies for T-cell lymphoma
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P2860
Regulation of CXC chemokine receptor 4-mediated migration by the Tec family tyrosine kinase ITK.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Regulation of CXC chemokine re ...... ec family tyrosine kinase ITK.
@en
Regulation of CXC chemokine re ...... ec family tyrosine kinase ITK.
@nl
type
label
Regulation of CXC chemokine re ...... ec family tyrosine kinase ITK.
@en
Regulation of CXC chemokine re ...... ec family tyrosine kinase ITK.
@nl
prefLabel
Regulation of CXC chemokine re ...... ec family tyrosine kinase ITK.
@en
Regulation of CXC chemokine re ...... ec family tyrosine kinase ITK.
@nl
P2093
P2860
P356
P1476
Regulation of CXC chemokine re ...... ec family tyrosine kinase ITK.
@en
P2093
Angela M Fischer
Archana Iyer
Avery August
Jason C Mercer
Melanie J Ragin
P2860
P304
29816-29820
P356
10.1074/JBC.M312848200
P407
P577
2004-04-26T00:00:00Z