Treatment of mice with 2,3,7,8-tetrachlorodibenzo-p-dioxin leads to aryl hydrocarbon receptor-dependent nuclear translocation of NF-kappaB and expression of Fas ligand in thymic stromal cells and consequent apoptosis in T cells.
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Contributions of nonhematopoietic cells and mediators to immune responses: implications for immunotoxicologyRelB, a new partner of aryl hydrocarbon receptor-mediated transcriptionActivation of aryl hydrocarbon receptor (AhR) leads to reciprocal epigenetic regulation of FoxP3 and IL-17 expression and amelioration of experimental colitisCausal effects of synthetic chemicals on mitochondrial deficits and diabetes pandemic.Evidence for ligand-mediated selective modulation of aryl hydrocarbon receptor activity.Primary peripheral T cells become susceptible to 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated apoptosis in vitro upon activation and in the presence of dendritic cellsUse of natural AhR ligands as potential therapeutic modalities against inflammatory disorders.Effects of TCDD on the fate of naive dendritic cells.Functional characterization and gene expression analysis of CD4+ CD25+ regulatory T cells generated in mice treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin.Dioxin may promote inflammation-related development of endometriosis.The aryl hydrocarbon receptor affects distinct tissue compartments during ontogeny of the immune system.EZR1: a novel family of highly expressed retroelements induced by TCDD and regulated by a NF-κB-like factor in embryos of zebrafish (Danio rerio).Differential proteomics analysis reveals a role for E2F2 in the regulation of the Ahr pathway in T lymphocytes.Prenatal exposure to TCDD triggers significant modulation of microRNA expression profile in the thymus that affects consequent gene expressionEffects of developmental activation of the AhR on CD4+ T-cell responses to influenza virus infection in adult mice.Gene expression alterations in immune system pathways in the thymus after exposure to immunosuppressive chemicals.Resveratrol (3,5,4'-trihydroxystilbene) protects pregnant mother and fetus from the immunotoxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin.A single mid-gestation exposure to TCDD yields a postnatal autoimmune signature, differing by sex, in early geriatric C57BL/6 mice.Activation of the aryl hydrocarbon receptor during development enhances the pulmonary CD4+ T-cell response to viral infection.Prenatal exposure of mice to diethylstilbestrol disrupts T-cell differentiation by regulating Fas/Fas ligand expression through estrogen receptor element and nuclear factor-κB motifs.Developmental Activation of the AHR Increases Effector CD4+ T Cells and Exacerbates Symptoms in Autoimmune Disease-Prone Gnaq+/- Mice.Lipopolysaccharide potentiates polychlorinated biphenyl-induced disruption of the blood-brain barrier via TLR4/IRF-3 signalingResveratrol (trans-3,5,4'-trihydroxystilbene) suppresses EL4 tumor growth by induction of apoptosis involving reciprocal regulation of SIRT1 and NF-κBDioxin exposure reduces the steroidogenic capacity of mouse antral follicles mainly at the level of HSD17B1 without altering atresia.Resveratrol (trans-3,5,4'-trihydroxystilbene) ameliorates experimental allergic encephalomyelitis, primarily via induction of apoptosis in T cells involving activation of aryl hydrocarbon receptor and estrogen receptor.Inflammatory signaling and aryl hydrocarbon receptor mediate synergistic induction of interleukin 6 in MCF-7 cells.Aryl hydrocarbon receptor and lung cancer."Omics" Technologies and the Immune System (a) , (b).Dioxin toxicity, aryl hydrocarbon receptor signaling, and apoptosis-persistent pollutants affect programmed cell death.The aryl hydrocarbon receptor and food allergy.Aryl hydrocarbon receptor in association with RelA modulates IL-6 expression in non-smoking lung cancer.The LMP1 promoter can be transactivated directly by NF-kappaB.Functional and phenotypic effects of AhR activation in inflammatory dendritic cells.Mid-gestation exposure of C57BL/6 mice to 2,3,7,8-tetrachlorodibenzo-p-dioxin causes postnatal morphologic changes in the spleen and liver.Constitutively active aryl hydrocarbon receptor expressed in T cells increases immunization-induced IFN-gamma production in mice but does not suppress T(h)2-cytokine production or antibody production.Thymic function in the regulation of T cells, and molecular mechanisms underlying the modulation of cytokines and stress signaling (Review).The highly bioactive molecule and signal substance 6-formylindolo[3,2-b]carbazole (FICZ) plays bi-functional roles in cell growth and apoptosis in vitro.2,3,7,8-Tetrachlorodibenzo-p-dioxin promotes astrocyte activation and the secretion of tumor necrosis factor-α via PKC/SSeCKS-dependent mechanisms.Olive oil and its phenolic compounds (hydroxytyrosol and tyrosol) ameliorated TCDD-induced heptotoxicity in rats via inhibition of oxidative stress and apoptosis.Genetic background and window of exposure contribute to thyroid dysfunction promoted by low-dose exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice
P2860
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P2860
Treatment of mice with 2,3,7,8-tetrachlorodibenzo-p-dioxin leads to aryl hydrocarbon receptor-dependent nuclear translocation of NF-kappaB and expression of Fas ligand in thymic stromal cells and consequent apoptosis in T cells.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
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2005年學術文章
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name
Treatment of mice with 2,3,7,8 ...... nsequent apoptosis in T cells.
@en
Treatment of mice with 2,3,7,8 ...... nsequent apoptosis in T cells.
@nl
type
label
Treatment of mice with 2,3,7,8 ...... nsequent apoptosis in T cells.
@en
Treatment of mice with 2,3,7,8 ...... nsequent apoptosis in T cells.
@nl
prefLabel
Treatment of mice with 2,3,7,8 ...... nsequent apoptosis in T cells.
@en
Treatment of mice with 2,3,7,8 ...... nsequent apoptosis in T cells.
@nl
P2093
P1476
Treatment of mice with 2,3,7,8 ...... onsequent apoptosis in T cells
@en
P2093
Iris A Camacho
Mitzi Nagarkatti
Narendra Singh
Prakash S Nagarkatti
P304
P356
10.4049/JIMMUNOL.175.1.90
P407
P577
2005-07-01T00:00:00Z