Mechanisms of interactions of factor X and factor Xa with the acidic region in the factor VIII A1 domain.
about
Interaction between mouse adenovirus type 1 and cell surface heparan sulfate proteoglycans.Sequences flanking Arg336 in factor VIIIa modulate factor Xa-catalyzed cleavage rates at this site and cofactor function.Targeting exosites on blood coagulation proteases.Ixolaris binding to factor X reveals a precursor state of factor Xa heparin-binding exosite.Identification of 31 novel mutations in the F8 gene in Spanish hemophilia A patients: structural analysis of 20 missense mutations suggests new intermolecular binding sites.Does plasmin have anticoagulant activity?Role of P1 residues Arg336 and Arg562 in the activated-Protein-C-catalysed inactivation of Factor VIIIa.Exosite-interactive regions in the A1 and A2 domains of factor VIII facilitate thrombin-catalyzed cleavage of heavy chain.The factor VIIIa C2 domain (residues 2228-2240) interacts with the factor IXa Gla domain in the factor Xase complex.Stable complex formation between serine protease inhibitor and zymogen: coagulation factor X cleaves the Arg393-Ser394 bond in a reactive centre loop of antithrombin in the presence of heparin.
P2860
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P2860
Mechanisms of interactions of factor X and factor Xa with the acidic region in the factor VIII A1 domain.
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name
Mechanisms of interactions of ...... in the factor VIII A1 domain.
@en
Mechanisms of interactions of ...... in the factor VIII A1 domain.
@nl
type
label
Mechanisms of interactions of ...... in the factor VIII A1 domain.
@en
Mechanisms of interactions of ...... in the factor VIII A1 domain.
@nl
prefLabel
Mechanisms of interactions of ...... in the factor VIII A1 domain.
@en
Mechanisms of interactions of ...... in the factor VIII A1 domain.
@nl
P2093
P2860
P356
P1476
Mechanisms of interactions of ...... in the factor VIII A1 domain.
@en
P2093
Alireza R Rezaie
Chandrashekhara Manithody
Hironao Wakabayashi
Keiji Nogami
Philip J Fay
P2860
P304
33104-33113
P356
10.1074/JBC.M405537200
P407
P577
2004-05-27T00:00:00Z