Localization of the binding regions of a murine monoclonal anti-factor VIII antibody and a human anti-factor VIII alloantibody, both of which inhibit factor VIII procoagulant activity, to amino acid residues threonine351-serine365 of the factor VIII
about
Inhibition of human factor VIIIa by anti-A2 subunit antibodies.Haemophilia A: effects of inhibitory antibodies on factor VIII functional interactions and approaches to prevent their action.Molecular basis of factor VIII inhibition by human antibodies. Antibodies that bind to the factor VIII light chain prevent the interaction of factor VIII with phospholipid.The concept of idiotypic vaccination against factor VIII inhibitors in haemophilia A.Pathophysiology of inhibitors to factor VIII in patients with haemophilia A.The molecular basis of hemophilia A.Natural antibodies to factor VIII (anti-hemophilic factor) in healthy individuals.Mutations and a polymorphism in the factor VIII gene discovered by denaturing gradient gel electrophoresisInhibition of human coagulation factor VIII by monoclonal antibodies. Mapping of functional epitopes with the use of recombinant factor VIII fragments.Thrombin-catalyzed activation of factor VIII with His substituted for Arg372 at the P1 siteUse of affinity-directed liquid chromatography-mass spectrometry to map the epitopes of a factor VIII inhibitor antibody fraction.Identification of a factor Xa-interactive site within residues 337-372 of the factor VIII heavy chain.Mechanisms of interactions of factor X and factor Xa with the acidic region in the factor VIII A1 domain.Exosite-interactive regions in the A1 and A2 domains of factor VIII facilitate thrombin-catalyzed cleavage of heavy chain.Contribution of factor VIII light-chain residues 2007-2016 to an activated protein C-interactive site.
P2860
Q34151336-CB5A887F-DFE9-4EEC-A23C-B868CA95F1EDQ34557048-6FC7E651-CBF5-4716-9FF2-3553F189ED82Q34575122-944A7673-6643-45CA-8DDB-D749037538E3Q34609618-0B928588-A59D-4038-8EC6-E9CD33B5E85CQ34636981-EA72937F-CF06-474C-9801-4AFA3D088CC9Q34886372-9CCEBA6D-D935-46E6-A4DE-56FA8FE3F9DEQ37599118-835A4F80-E683-42AF-B60A-5F865244D185Q37717801-ECEC90A8-6D04-447F-8799-654F4A8520AFQ41258205-3AB9AD02-5888-41F8-8E36-571DA07E0BB3Q42742776-B4B3DF4B-58CB-4D67-A250-84A132C59DD6Q42864630-04DBA68E-7442-4E90-BC7E-4D97A8FF134BQ44756930-7E36991B-5164-4042-831B-D88B02C8B812Q44912906-023AC85E-DDDA-4121-82BD-0E01C50A9722Q45881688-7D3A7144-911A-48B6-9BB5-09253535209CQ53130327-A8DE6DCE-E39C-4742-9F38-1A946604820D
P2860
Localization of the binding regions of a murine monoclonal anti-factor VIII antibody and a human anti-factor VIII alloantibody, both of which inhibit factor VIII procoagulant activity, to amino acid residues threonine351-serine365 of the factor VIII
description
1988 nî lūn-bûn
@nan
1988 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Localization of the binding re ...... 1-serine365 of the factor VIII
@ast
Localization of the binding re ...... 1-serine365 of the factor VIII
@en
Localization of the binding re ...... 1-serine365 of the factor VIII
@nl
type
label
Localization of the binding re ...... 1-serine365 of the factor VIII
@ast
Localization of the binding re ...... 1-serine365 of the factor VIII
@en
Localization of the binding re ...... 1-serine365 of the factor VIII
@nl
prefLabel
Localization of the binding re ...... 1-serine365 of the factor VIII
@ast
Localization of the binding re ...... 1-serine365 of the factor VIII
@en
Localization of the binding re ...... 1-serine365 of the factor VIII
@nl
P2093
P2860
P356
P1476
Localization of the binding re ...... 1-serine365 of the factor VIII
@en
P2093
C A Fulcher
P A Foster
R A Houghten
S de Graaf Mahoney
T S Zimmerman
P2860
P304
P356
10.1172/JCI113559
P407
P577
1988-07-01T00:00:00Z