Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils. - Wikidata - awgldk - TriplyDB

Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils.

Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils.

http://www.wikidata.org/entity/Q44915718

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Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix.GBF1 bears a novel phosphatidylinositol-phosphate binding module, BP3K, to link PI3Kγ activity with Arf1 activation involved in GPCR-mediated neutrophil chemotaxis and superoxide production Involvement of the Rho/Rac family member RhoG in caveolar endocytosis Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease Parallel phosphatidylinositol 3-kinase (PI3K)-dependent and Src-dependent pathways lead to CXCL8-mediated Rac2 activation and chemotaxis Rho GTPases in hematopoiesis and hemopathies GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo The Rac1 hypervariable region in targeting and signaling: a tail of many stories Actin cytoskeletal defects in immunodeficiency Mitochondrial Dysfunction in Human Leukemic Stem/Progenitor Cells upon Loss of RAC2 The adhesion GPCR BAI1 mediates macrophage ROS production and microbicidal activity against Gram-negative bacteria.Neutrophil recruitment limited by high-affinity bent β2 integrin binding ligand in cis.Activation and assembly of the NADPH oxidase: a structural perspective RhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte development Inositol trisphosphate 3-kinase B (InsP3KB) as a physiological modulator of myelopoiesis SCFAs induce mouse neutrophil chemotaxis through the GPR43 receptor The small Rho GTPase Cdc42 regulates neutrophil polarity via CD11b integrin signaling Cdc42 regulates neutrophil migration via crosstalk between WASp, CD11b, and microtubules The Rac GTPase effector p21-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment.Optical Tools To Study the Isoform-Specific Roles of Small GTPases in Immune Cells.T cell LFA-1 engagement induces HuR-dependent cytokine mRNA stabilization through a Vav-1, Rac1/2, p38MAPK and MKK3 signaling cascade ROS-inhibitory activity of YopE is required for full virulence of Yersinia in mice Macrophages are targeted by rotavirus in experimental biliary atresia and induce neutrophil chemotaxis by Mip2/Cxcl2.Concise review: polarity in stem cells, disease, and aging.Signaling protein SWAP-70 is required for efficient B cell homing to lymphoid organs.Rac2-deficiency leads to exacerbated and protracted colitis in response to Citrobacter rodentium infection Altered cellular dynamics and endosteal location of aged early hematopoietic progenitor cells revealed by time-lapse intravital imaging in long bones.Agonist activation of f-actin-mediated eosinophil shape change and mediator release is dependent on Rac2.Granulocyte-derived cationic Peptide enhances homing and engraftment of bone marrow stem cells after transplantation.Dual roles for Rac2 in neutrophil motility and active retention in zebrafish hematopoietic tissue.Involvement of Fyn kinase in Kit and integrin-mediated Rac activation, cytoskeletal reorganization, and chemotaxis of mast cells.CXCL9 inhibits eosinophil responses by a CCR3- and Rac2-dependent mechanism.DOCK2 and DOCK5 act additively in neutrophils to regulate chemotaxis, superoxide production, and extracellular trap formation Cross-talk between RhoH and Rac1 in regulation of actin cytoskeleton and chemotaxis of hematopoietic progenitor cells Targeting and localized signalling by small GTPases.Phospholipase D activity regulates integrin-mediated cell spreading and migration by inducing GTP-Rac translocation to the plasma membrane.Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins Rho GTPases in hematopoietic stem cell functions Regulation of inflammation by Rac2 in immune complex-mediated acute lung injury Mechanisms of degranulation in neutrophils.

P2860

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P2860

Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils.

http://www.wikidata.org/entity/Q44915718

description

2004 nî lūn-bûn

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2004年の論文

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年學術文章

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2004年學術文章

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2004年學術文章

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name

Localization of Rac2 via the C ...... and chemotaxis in neutrophils.

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Localization of Rac2 via the C ...... and chemotaxis in neutrophils.

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type

label

Localization of Rac2 via the C ...... and chemotaxis in neutrophils.

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Localization of Rac2 via the C ...... and chemotaxis in neutrophils.

@nl

prefLabel

Localization of Rac2 via the C ...... and chemotaxis in neutrophils.

@en

Localization of Rac2 via the C ...... and chemotaxis in neutrophils.

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Nature Immunology

P1476

Localization of Rac2 via the C ...... and chemotaxis in neutrophils

@en

P2093

Chad E Harris

http://www.w3.org/2001/XMLSchema#string

David A Williams

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Marie-Dominique Filippi

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Yi Gu

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Yi Zheng

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P2860

Characterization of RAC3, a novel member of the Rho family

Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding

Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation

The Rac-RhoGDI complex and the structural basis for the regulation of Rho proteins by RhoGDI

Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI

Rac2 stimulates Akt activation affecting BAD/Bcl-XL expression while mediating survival and actin function in primary mast cells

Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense

Rho GTPases and signaling networks

Structural requirements for PAK activation by Rac GTPases

Protein prenylation: molecular mechanisms and functional consequences

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744-751

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10.1038/NI1081

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