Resolution of conformational activation in the kinetic mechanism of plasminogen activation by streptokinase.
about
Fibrinogen substrate recognition by staphylocoagulase.(pro)thrombin complexesSkizzle is a novel plasminogen- and plasmin-binding protein from Streptococcus agalactiae that targets proteins of human fibrinolysis to promote plasmin generationInhibitor of streptokinase gene expression improves survival after group A streptococcus infection in miceRapid binding of plasminogen to streptokinase in a catalytic complex reveals a three-step mechanism.Engineering streptokinase for generation of active site-labeled plasminogen analogs.Pathogen activators of plasminogenActivity Regulation by Fibrinogen and Fibrin of Streptokinase from Streptococcus Pyogenes.Binding of the COOH-terminal lysine residue of streptokinase to plasmin(ogen) kringles enhances formation of the streptokinase.plasmin(ogen) catalytic complexes.Role of the streptokinase alpha-domain in the interactions of streptokinase with plasminogen and plasminStructural basis for reduced staphylocoagulase-mediated bovine prothrombin activationFull time course kinetics of the streptokinase-plasminogen activation pathway.Plasminogen substrate recognition by the streptokinase-plasminogen catalytic complex is facilitated by Arg253, Lys256, and Lys257 in the streptokinase beta-domain and kringle 5 of the substrate.Natural and engineered plasmin inhibitors: applications and design strategies.Interaction of streptococcal plasminogen binding proteins with the host fibrinolytic system.Identification of a new exosite involved in catalytic turnover by the streptokinase-plasmin activator complex during human plasminogen activation.Site-restricted plasminogen activation mediated by group A streptococcal streptokinase variants.Rapid-reaction kinetic characterization of the pathway of streptokinase-plasmin catalytic complex formation.Identification through combinatorial random and rational mutagenesis of a substrate-interacting exosite in the gamma domain of streptokinase.Coupling of conformational and proteolytic activation in the kinetic mechanism of plasminogen activation by streptokinase.A synthetic peptide derived from staphylokinase enhances plasminogen activation by tissue-type plasminogen activator.
P2860
Q24338455-FC52D1F3-65CA-4779-B2C2-37ECF6E85A5AQ33966955-47C8AD15-6DEE-4C96-A867-BE48F4B336C2Q34158204-6DB789D0-50F0-4440-A62C-C7292DF189B4Q34283594-75C1681A-63B0-4094-8E33-DF3996E49375Q35042660-4BA22A0F-CF9B-4EE0-8AA3-BD19860A2B12Q35838180-A33C1732-431B-4FA2-8127-1451BB10CD93Q36261579-99A0F752-E84F-41A2-A2FB-FA15D29AE10CQ36536357-C4728462-7C6D-45ED-81B8-AC1112C3B28CQ36538510-E9B3B5F4-D36D-49FE-A580-B27554620BCDQ36538515-D49480F7-2C3E-44BE-BFF2-D7C58BBF9A5AQ37226126-7ABD03BC-FA2D-4C76-A48F-84C849A13207Q37339330-79717D3B-68A3-481E-938C-22485E0A3BB6Q37975189-E899ADDC-C30D-4396-BA37-47E52CAE2148Q38169715-5325355E-84C6-465E-9839-EF852D29E55BQ41965533-5152993D-CBC4-4580-9798-1E392BEDC5DCQ42239662-02669F34-D93A-4FBF-B551-D0FF35B3A90BQ42458195-134248D2-B947-445A-9CAE-87AA5BB7A162Q42691876-DDAF9B29-1983-4EC6-AD81-F293255C4CC7Q44950426-151CB735-53BD-4916-B104-30CF88281899Q53262163-2F3AD288-70BA-40A3-9E90-BC682DB3B43D
P2860
Resolution of conformational activation in the kinetic mechanism of plasminogen activation by streptokinase.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Resolution of conformational a ...... n activation by streptokinase.
@en
Resolution of conformational a ...... n activation by streptokinase.
@nl
type
label
Resolution of conformational a ...... n activation by streptokinase.
@en
Resolution of conformational a ...... n activation by streptokinase.
@nl
prefLabel
Resolution of conformational a ...... n activation by streptokinase.
@en
Resolution of conformational a ...... n activation by streptokinase.
@nl
P2860
P356
P1476
Resolution of conformational a ...... n activation by streptokinase.
@en
P2093
Paul D Boxrud
P2860
P304
36633-36641
P356
10.1074/JBC.M405264200
P407
P577
2004-06-23T00:00:00Z