ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE.
about
Interactions of metals and Apolipoprotein E in Alzheimer's diseaseThe cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor proteinImpact of apolipoprotein E on Alzheimer's diseaseApolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapyApoE promotes the proteolytic degradation of AbetaAmyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1Fetal Alcohol Spectrum Disorders: An Overview from the Glia PerspectiveMammalian P4-ATPases and ABC transporters and their role in phospholipid transportFrom evolution to revolution: miRNAs as pharmacological targets for modulating cholesterol efflux and reverse cholesterol transportDysregulation of cholesterol balance in the brain: contribution to neurodegenerative diseasesOxidized cholesterol as the driving force behind the development of Alzheimer's diseaseThe liver X receptor agonist GW3965 improves recovery from mild repetitive traumatic brain injury in mice partly through apolipoprotein EAbsence of apolipoprotein E protects mice from cerebral malariaACAT1/SOAT1 as a therapeutic target for Alzheimer's diseaseAPOE-modulated Aβ-induced neuroinflammation in Alzheimer's disease: current landscape, novel data, and future perspectiveMolecular mechanisms of cognitive dysfunction following traumatic brain injuryInteractions between inflammation, sex steroids, and Alzheimer's disease risk factorsIdentification of a Chrysanthemic Ester as an Apolipoprotein E Inducer in AstrocytesLiver X receptors regulate cholesterol homeostasis in oligodendrocytesLCAT synthesized by primary astrocytes esterifies cholesterol on glia-derived lipoproteinsInfluence of four polymorphisms in ABCA1 and PTGS2 genes on risk of Alzheimer's disease: a meta-analysis.Ethanol induces cholesterol efflux and up-regulates ATP-binding cassette cholesterol transporters in fetal astrocytes.Specific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function.ATP-binding cassette transporter A1 mediates the beneficial effects of the liver X receptor agonist GW3965 on object recognition memory and amyloid burden in amyloid precursor protein/presenilin 1 mice.Epigenetic signature and enhancer activity of the human APOE gene.Opposing effects of Apoe/Apoa1 double deletion on amyloid-β pathology and cognitive performance in APP mice.Survival of adult neurons lacking cholesterol synthesis in vivo.The effect of ABCA1 gene polymorphisms on ischaemic stroke risk and relationship with lipid profile.Metals and cholesterol: two sides of the same coin in Alzheimer's disease pathology.Retinoic acid isomers facilitate apolipoprotein E production and lipidation in astrocytes through the retinoid X receptor/retinoic acid receptor pathway.An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain CancersLiver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice.LCAT deficiency does not impair amyloid metabolism in APP/PS1 miceThe C-terminal alpha-helix domain of apolipoprotein E is required for interaction with nonstructural protein 5A and assembly of hepatitis C virus.Apolipoprotein A-I deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1DeltaE9 miceAmyloid-β pathology and APOE genotype modulate retinoid X receptor agonist activity in vivo.Glia and neurodevelopment: focus on fetal alcohol spectrum disorders.Apolipoprotein E: from lipid transport to neurobiologyThe role of apolipoprotein E in Alzheimer's disease.HDL and cognition in neurodegenerative disorders.
P2860
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P2860
ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
ABCA1 is required for normal c ...... on of astrocyte-secreted apoE.
@en
ABCA1 is required for normal c ...... on of astrocyte-secreted apoE.
@nl
type
label
ABCA1 is required for normal c ...... on of astrocyte-secreted apoE.
@en
ABCA1 is required for normal c ...... on of astrocyte-secreted apoE.
@nl
prefLabel
ABCA1 is required for normal c ...... on of astrocyte-secreted apoE.
@en
ABCA1 is required for normal c ...... on of astrocyte-secreted apoE.
@nl
P2093
P356
P1476
ABCA1 is required for normal c ...... on of astrocyte-secreted apoE.
@en
P2093
Hong Jiang
John D Fryer
Justin Legleiter
Maia Parsadanian
Suzanne E Wahrle
Xianlin Han
P304
40987-40993
P356
10.1074/JBC.M407963200
P407
P577
2004-07-21T00:00:00Z