A dileucine motif and a cluster of acidic amino acids in the second cytoplasmic domain of the batten disease-related CLN3 protein are required for efficient lysosomal targeting.
about
An unconventional dileucine-based motif and a novel cytosolic motif are required for the lysosomal and melanosomal targeting of OA1Lysosomal membrane proteins and their central role in physiologyMucolipidosis II is caused by mutations in GNPTA encoding the alpha/beta GlcNAc-1-phosphotransferaseInteractions of the proteins of neuronal ceroid lipofuscinosis: clues to functionInteraction between Sdo1p and Btn1p in the Saccharomyces cerevisiae model for Batten disease.Two dileucine motifs mediate late endosomal/lysosomal targeting of transmembrane protein 192 (TMEM192) and a C-terminal cysteine residue is responsible for disulfide bond formation in TMEM192 homodimers.The juvenile Batten disease protein, CLN3, and its role in regulating anterograde and retrograde post-Golgi trafficking.Functional analysis of two single nucleotide polymorphisms in SLC30A2 (ZnT2): implications for mammary gland function and breast disease in womenOsmotic stress changes the expression and subcellular localization of the Batten disease protein CLN3.BTN1, the Saccharomyces cerevisiae homolog to the human Batten disease gene, is involved in phospholipid distribution.Regulation of Monocarboxylic Acid Transporter 1 Trafficking by the Canonical Wnt/β-Catenin Pathway in Rat Brain Endothelial Cells Requires Cross-talk with Notch SignalingCathepsin proteases in Toxoplasma gondii.Update of the mutation spectrum and clinical correlations of over 360 mutations in eight genes that underlie the neuronal ceroid lipofuscinoses.Traffic routes and signals for the tonoplast.Subcellular Trafficking of Mammalian Lysosomal Proteins: An Extended View.AP-1 and AP-3 facilitate lysosomal targeting of Batten disease protein CLN3 via its dileucine motif.pH-dependent localization of Btn1p in the yeast model for Batten diseaseThe fission yeast model for the lysosomal storage disorder Batten disease predicts disease severity caused by mutations in CLN3.Proteolytic processing of the gamma-subunit is associated with the failure to form GlcNAc-1-phosphotransferase complexes and mannose 6-phosphate residues on lysosomal enzymes in human macrophages.Determinants for Arabidopsis peptide transporter targeting to the tonoplast or plasma membrane.Lack of specificity of antibodies raised against CLN3, the lysosomal/endosomal transmembrane protein mutated in juvenile Batten disease.Revisiting the neuronal localization and trafficking of CLN3 in juvenile neuronal ceroid lipofuscinosis.C-terminal prenylation of the CLN3 membrane glycoprotein is required for efficient endosomal sorting to lysosomes.
P2860
Q24318501-18C8395E-3862-4A18-B30F-1774C2EA67F7Q27013815-F18CEB96-93EE-4EB7-B6A2-D01E5EF2BEB2Q28275193-6112253D-02A4-4223-A56A-EB943410CC16Q28289653-50E2CE9C-4A18-42E2-A550-F81686A15A75Q33630706-ED3BBB61-153F-45F3-9BF7-ED1D8C7CDCF6Q34153945-CABC21EB-7369-4BE1-B066-DB59E576B62CQ34271805-43F4FE4E-7CDD-4691-8717-7EE9E1A94856Q34432762-3FE14DCE-DFAF-47FA-9609-C7F1B283BB95Q34805162-304FA51E-788D-4C5B-B3C5-512B3B84BBFEQ35794562-0C250736-3F7B-4365-B630-CB0452664234Q36778818-C7126FA9-1B00-4A9F-8928-7D714D6F52A9Q37635978-5701BF9D-E830-4671-A672-A9CF82212DFBQ37944570-9683187C-871A-436F-860C-C9AE949A0411Q38077271-6F3037E5-F474-4EC1-A23D-4433E3C3D890Q39063017-F2E9451C-2E93-4727-A115-03870DA80EC6Q40480798-82C027C9-210E-4394-9AF6-AEA73C7C834AQ41441947-91396262-4201-4933-93BC-4FABD7F71C24Q42040450-83A0FCE6-2C13-409E-BE8C-73097A783B27Q42681492-F993D84B-6FDB-4B5A-8036-70DCC5E8B2D6Q46038285-2F06F928-9D66-4823-83C7-D6B1D61CC31FQ47134547-71A44557-F667-428D-BE94-BC812845D2F6Q48465441-332F1B78-F8BE-484A-B069-C3B1D3BCBC1BQ55043107-06BD54AD-786F-4201-87EB-80E984017D62
P2860
A dileucine motif and a cluster of acidic amino acids in the second cytoplasmic domain of the batten disease-related CLN3 protein are required for efficient lysosomal targeting.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
A dileucine motif and a cluste ...... efficient lysosomal targeting.
@en
A dileucine motif and a cluste ...... efficient lysosomal targeting.
@nl
type
label
A dileucine motif and a cluste ...... efficient lysosomal targeting.
@en
A dileucine motif and a cluste ...... efficient lysosomal targeting.
@nl
prefLabel
A dileucine motif and a cluste ...... efficient lysosomal targeting.
@en
A dileucine motif and a cluste ...... efficient lysosomal targeting.
@nl
P2093
P2860
P356
P1476
A dileucine motif and a cluste ...... efficient lysosomal targeting.
@en
P2093
Sandra Pohl
Stephan Storch
Thomas Braulke
P2860
P304
53625-53634
P356
10.1074/JBC.M410930200
P407
P577
2004-10-05T00:00:00Z