CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas. - Wikidata - awgldk - TriplyDB

CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas.

CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas.

http://www.wikidata.org/entity/Q45182713

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Oligodendroglioma: pathology, molecular mechanisms and markers Molecular Markers in Low-Grade Glioma-Toward Tumor Reclassification Genetic Predisposition to Weight Loss and Regain With Lifestyle Intervention: Analyses From the Diabetes Prevention Program and the Look AHEAD Randomized Controlled Trials.Molecular Testing of Brain Tumor.Glioma diagnostics and biomarkers: an ongoing challenge in the field of medicine and science The splicing factor FUBP1 is required for the efficient splicing of oncogene MDM2 pre-mRNA.Comparative transcriptome analysis of isogenic cell line models and primary cancers links capicua (CIC) loss to activation of the MAPK signalling cascade Distinct transcriptional signature and immunoprofile of CIC-DUX4 fusion-positive round cell tumors compared to EWSR1-rearranged Ewing sarcomas: further evidence toward distinct pathologic entities.Mutations in CIC and IDH1 cooperatively regulate 2-hydroxyglutarate levels and cell clonogenicity SNP array analysis reveals novel genomic abnormalities including copy neutral loss of heterozygosity in anaplastic oligodendrogliomas.A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1.Novel CIC point mutations and an exon-spanning, homozygous deletion identified in oligodendroglial tumors by a comprehensive genomic approach including transcriptome sequencing.IDH1 mutant malignant astrocytomas are more amenable to surgical resection and have a survival benefit associated with maximal surgical resection Tumor-specific mutations in low-frequency genes affect their functional properties.Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas.Upregulation of Far Upstream Element-Binding Protein 1 (FUBP1) Promotes Tumor Proliferation and Tumorigenesis of Clear Cell Renal Cell Carcinoma.A model of a patient-derived IDH1 mutant anaplastic astrocytoma with alternative lengthening of telomeres A new mode of DNA binding distinguishes Capicua from other HMG-box factors and explains its mutation patterns in cancer.Personalized care in neuro-oncology coming of age: why we need MGMT and 1p/19q testing for malignant glioma patients in clinical practice.Isocitrate dehydrogenase mutations in gliomas Influence of far upstream element binding protein 1 gene on chemotherapy sensitivity in human U251 glioblastoma cells.What do we know about IDH1/2 mutations so far, and how do we use it?Recurrent CIC Gene Abnormalities in Angiosarcomas: A Molecular Study of 120 Cases With Concurrent Investigation of PLCG1, KDR, MYC, and FLT4 Gene Alterations.Minibrain and Wings apart control organ growth and tissue patterning through down-regulation of Capicua Not all 1p/19q non-codeleted oligodendroglial tumors are astrocytic.IDH1 and IDH2 mutations in tumorigenesis: mechanistic insights and clinical perspectives Emerging biomarkers in anaplastic oligodendroglioma: implications for clinical investigation and patient management.Isocitrate dehydrogenase 1 and 2 mutations in gliomas.The evolving molecular genetics of low-grade glioma.ZEB1 expression is increased in IDH1-mutant lower-grade gliomas.Anaplastic glioma: current treatment and management.Diagnostic, prognostic and predictive relevance of molecular markers in gliomas.Applicable advances in the molecular pathology of glioblastoma.Molecular profiling of gliomas: potential therapeutic implications.Molecular background of oligodendroglioma: 1p/19q, IDH, TERT, CIC and FUBP1.The Diagnostic Use of Immunohistochemical Surrogates for Signature Molecular Genetic Alterations in Gliomas.Head and Neck Round Cell Sarcomas: A Comparative Clinicopathologic Analysis of 2 Molecular Subsets: Ewing and CIC-Rearranged Sarcomas.Classification of adult diffuse gliomas by molecular markers-a short review with historical footnote.The new WHO 2016 classification of brain tumors-what neurosurgeons need to know.Upregulating mutations in the TERT promoter commonly occur in adult malignant gliomas and are strongly associated with total 1p19q loss.

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CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas.

http://www.wikidata.org/entity/Q45182713

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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name

CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas.

@en

CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas.

@nl

type

label

CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas.

@en

CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas.

@nl

prefLabel

CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas.

@en

CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas.

@nl

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S00401-012-0993-5

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Acta Neuropathologica

P1476

CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas.

@en

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Christian Hartmann

http://www.w3.org/2001/XMLSchema#string

Christian Koelsche

http://www.w3.org/2001/XMLSchema#string

Jochen Meyer

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Kerstin Lindenberg

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Wolf Mueller

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P2860

A sequence-specific, single-strand binding protein activates the far upstream element of c-myc and defines a new DNA-binding motif

Mutations in CIC and FUBP1 contribute to human oligodendroglioma

The genetic landscape of the childhood cancer medulloblastoma

CIC, a member of a novel subfamily of the HMG-box superfamily, is transiently expressed in developing granule neurons.

CIC, a gene involved in cerebellar development and ErbB signaling, is significantly expressed in medulloblastomas.

Analysis of the IDH1 codon 132 mutation in brain tumors.

Overexpression of the far upstream element binding protein 1 in hepatocellular carcinoma is required for tumor growth.

Gene regulation by MAPK substrate competition.

Overexpression of far upstream element binding proteins: a mechanism regulating proliferation and migration in liver cancer cells.

Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers.

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s00401-012-0993-5

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853-860

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scholarly article

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10.1007/S00401-012-0993-5

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6

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123

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Andreas von Deimling

Christel Herold-Mende

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2012-05-17T00:00:00Z

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1037252294

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22588899

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P921

oligodendroglioma