In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrase II. - Wikidata - awgldk - TriplyDB

In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrase II.

In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrase II.

http://www.wikidata.org/entity/Q45187955

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Crosslinking studies of protein-protein interactions in nonribosomal peptide biosynthesis Biotin Protein Ligase Is a Target for New Antibacterials In situ click chemistry: from small molecule discovery to synthetic antibodies Stereo- and regioselective azide/alkyne cycloadditions in carbonic anhydrase II via tethering, monitored by crystallography and mass spectrometry Generation of Candidate Ligands for Nicotinic Acetylcholine Receptors via in situ Click Chemistry with a Soluble Acetylcholine Binding Protein Template Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor Targeting mRNA for Alzheimer's and related dementias.Kinetic target-guided synthesis in drug discovery and chemical biology: a comprehensive facts and figures survey AutoClickChem: click chemistry in silico Increasing Tumor Accessibility with Conjugatable Disulfide-Bridged Tumor-Penetrating Peptides for Cancer Diagnosis and Treatment.Probing gorge dimensions of cholinesterases by freeze-frame click chemistry.Bcl-XL-templated assembly of its own protein-protein interaction modulator from fragments decorated with thio acids and sulfonyl azides.Integrated Microfluidic Reactors.In situ click chemistry generation of cyclooxygenase-2 inhibitors.Screening of protein-protein interaction modulators via sulfo-click kinetic target-guided synthesis An integrated microfluidic device for large-scale in situ click chemistry screening.e-LEA3D: a computational-aided drug design web server Recent development of two chitinase inhibitors, Argifin and Argadin, produced by soil microorganisms.The impact of click chemistry in medicinal chemistry.The growing applications of click chemistry.Synthesis of a trimeric gp120 epitope mimic conjugated to a T-helper peptide to improve antigenicity A General Synthetic Approach for Designing Epitope Targeted Macrocyclic Peptide Ligands A general chemical synthesis platform for crosslinking multivalent single chain variable fragments.Quick assembly of 1,4-diphenyltriazoles as probes targeting beta-amyloid aggregates in Alzheimer's disease.Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice Synthesis of selective agonists for the α7 nicotinic acetylcholine receptor with in situ click-chemistry on acetylcholine-binding protein templates.A new application of click chemistry in situ: development of fluorescent probe for specific G-quadruplex topology Iterative in situ click chemistry assembles a branched capture agent and allosteric inhibitor for Akt1.Carbonic anhydrase as a model for biophysical and physical-organic studies of proteins and protein-ligand binding.Probing secondary interactions in biomolecular recognition by dynamic combinatorial chemistry.The design of RNA binders: targeting the HIV replication cycle as a case study.New insights into the kinetic target-guided synthesis of protein ligands.Ribosome-Templated Azide-Alkyne Cycloadditions: Synthesis of Potent Macrolide Antibiotics by In Situ Click Chemistry.Synthesis and cytotoxicity evaluation of some novel thiazoles, thiadiazoles, and pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-ones incorporating triazole moiety.Design, synthesis, antiviral, and cytotoxic evaluation of novel phosphonylated 1,2,3-triazoles as acyclic nucleotide analogues.Probing the binding site of abl tyrosine kinase using in situ click chemistry.1,2,3-Triazole-based inhibitors of Porphyromonas gingivalis adherence to oral streptococci and biofilm formation.Target guided synthesis using DNA nano-templates for selectively assembling a G-quadruplex binding c-MYC inhibitor.cat-ELCCA: a robust method to monitor the fatty acid acyltransferase activity of ghrelin O-acyltransferase (GOAT).Selective RNA versus DNA G-quadruplex targeting by in situ click chemistry.

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P2860

In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrase II.

http://www.wikidata.org/entity/Q45187955

description

2004 nî lūn-bûn

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2004年の論文

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年學術文章

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2004年學術文章

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name

In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrase II.

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In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrase II.

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type

label

In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrase II.

@en

In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrase II.

@nl

prefLabel

In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrase II.

@en

In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrase II.

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P1433

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P1433

Angewandte Chemie International Edition

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In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrase II.

@en

P2093

Benoit Colasson

http://www.w3.org/2001/XMLSchema#string

Chi-Huey Wong

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Hartmuth C Kolb

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Lac V Lee

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Stefanie Röper

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Vani P Mocharla

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P2860

Site-directed ligand discovery

Unexpected formation of an epoxide-derived multisubstrate adduct inhibitor on the active site of GAR transformylase

Combinatorial computational method gives new picomolar ligands for a known enzyme

In situ assembly of enzyme inhibitors using extended tethering

Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation

Carbonic anhydrase inhibitors

A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes

Synthesis and biological evaluation of vancomycin dimers with potent activity against vancomycin-resistant bacteria: target-accelerated combinatorial synthesis.

In situ generation and screening of a dynamic combinatorial carbohydrate library against concanavalin A.

Drug discovery by dynamic combinatorial libraries.

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116-120

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scholarly article

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10.1002/ANIE.200461580

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1

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44

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Karl Barry Sharpless

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15599912

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