Selective inhibition of human cytochrome P4502C8 by montelukast. - Wikidata - awgldk - TriplyDB

Selective inhibition of human cytochrome P4502C8 by montelukast.

Selective inhibition of human cytochrome P4502C8 by montelukast.

http://www.wikidata.org/entity/Q45193687

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Determinants of Cytochrome P450 2C8 Substrate Binding: STRUCTURES OF COMPLEXES WITH MONTELUKAST, TROGLITAZONE, FELODIPINE, AND 9-CIS-RETINOIC ACID Metabolism of repaglinide by CYP2C8 and CYP3A4 in vitro: effect of fibrates and rifampicin.Maraviroc: in vitro assessment of drug-drug interaction potential Sucralose, a synthetic organochlorine sweetener: overview of biological issues Development of a Pediatric Physiologically Based Pharmacokinetic Model for Sirolimus: Applying Principles of Growth and Maturation in Neonates and Infants.Contributions of human cytochrome P450 enzymes to glyburide metabolism.Potential contribution of cytochrome P450 2B6 to hepatic 4-hydroxycyclophosphamide formation in vitro and in vivo CYP2C8 but not CYP3A4 is important in the pharmacokinetics of montelukast.Cytochrome P450 Oxidase 2C Inhibition Adds to ω-3 Long-Chain Polyunsaturated Fatty Acids Protection Against Retinal and Choroidal Neovascularization.In Vitro Metabolism of Montelukast by Cytochrome P450s and UDP-Glucuronosyltransferases Gomisin A is a Novel Isoform-Specific Probe for the Selective Sensing of Human Cytochrome P450 3A4 in Liver Microsomes and Living Cells.Cytochrome P450 reaction-phenotyping: an industrial perspective.In vitro evaluation of reversible and irreversible cytochrome P450 inhibition: current status on methodologies and their utility for predicting drug-drug interactions.Selective, competitive and mechanism-based inhibitors of human cytochrome P450 2J2.Therapeutic management of allergic diseases.Chemical inhibitors of cytochrome P450 isoforms in human liver microsomes: a re-evaluation of P450 isoform selectivity.Metabolic considerations of drugs in the treatment of allergic diseases.Characterization of cytochrome P450s mediating ipriflavone metabolism in human liver microsomes.Role of Cytochrome P450 2C8 in Drug Metabolism and Interactions.Evaluation of a New Molecular Entity as a Victim of Metabolic Drug-Drug Interactions-an Industry Perspective.Role of gemfibrozil as an inhibitor of CYP2C8 and membrane transporters.The impact of CYP3A5*3 polymorphism on sirolimus pharmacokinetics: insights from predictions with a physiologically-based pharmacokinetic model.Effect of multiple doses of montelukast on the pharmacokinetics of rosiglitazone, a CYP2C8 substrate, in humans Repaglinide-gemfibrozil drug interaction: inhibition of repaglinide glucuronidation as a potential additional contributing mechanism Gemfibrozil markedly increases the plasma concentrations of montelukast: a previously unrecognized role for CYP2C8 in the metabolism of montelukast.In vitro and in vivo studies to characterize the clearance mechanism and potential cytochrome P450 interactions of anidulafungin.CYP3A catalyses schizandrin biotransformation in human, minipig and rat liver microsomes.Inhibition of CYP3A4 and CYP2C9 by podophyllotoxin: implication for clinical drug-drug interactions.Effect of honokiol on cytochrome P450 and UDP-glucuronosyltransferase enzyme activities in human liver microsomes.Characterization of human cytochrome P450 isoforms involved in the metabolism of 7-epi-paclitaxel.The targeted oral, once-daily phosphodiesterase 4 inhibitor roflumilast and the leukotriene receptor antagonist montelukast do not exhibit significant pharmacokinetic interactions.Suspected adverse reactions associated with herbal products used for weight loss: a case series reported to the Italian National Institute of Health.Identification of putative substrates for cynomolgus monkey cytochrome P450 2C8 by substrate depletion assays with 22 human P450 substrates and inhibitors.Identification of cytochrome P450 enzymes responsible for N -dealkylation of a new oral erectogenic, mirodenafil.Characterization of novel CYP2C8 haplotypes and their contribution to paclitaxel and repaglinide metabolism.In vitro characterization of 4'-(p-toluenesulfonylamide)-4-hydroxychalcone using human liver microsomes and recombinant cytochrome P450s.In vitro metabolism of eupatilin by multiple cytochrome P450 and UDP-glucuronosyltransferase enzymes.Mechanism-Based Inactivation of CYP2C8 by Gemfibrozil Occurs Rapidly in Humans

P2860

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P2860

Selective inhibition of human cytochrome P4502C8 by montelukast.

http://www.wikidata.org/entity/Q45193687

description

2004 nî lūn-bûn

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2004年の論文

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

@zh-hans

2004年学术文章

@zh-my

2004年学术文章

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2004年學術文章

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2004年學術文章

@zh-hant

name

Selective inhibition of human cytochrome P4502C8 by montelukast.

@en

Selective inhibition of human cytochrome P4502C8 by montelukast.

@nl

type

label

Selective inhibition of human cytochrome P4502C8 by montelukast.

@en

Selective inhibition of human cytochrome P4502C8 by montelukast.

@nl

prefLabel

Selective inhibition of human cytochrome P4502C8 by montelukast.

@en

Selective inhibition of human cytochrome P4502C8 by montelukast.

@nl

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Drug Metabolism and Disposition

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Selective inhibition of human cytochrome P4502C8 by montelukast.

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P2093

Emily A Gaman

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Jean-Paul R Gleeson

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R Scott Obach

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Robert L Walsky

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William R Proctor

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scholarly article

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10.1124/DMD.104.002766

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3

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33

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2004-12-17T00:00:00Z

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8122200

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15608135

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