Selective, competitive and mechanism-based inhibitors of human cytochrome P450 2J2.
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Selective inhibitors of CYP2J2 related to terfenadine exhibit strong activity against human cancers in vitro and in vivoInducible CYP2J2 and its product 11,12-EET promotes bacterial phagocytosis: a role for CYP2J2 deficiency in the pathogenesis of Crohn's disease?Correlating chemical sensitivity and basal gene expression reveals mechanism of action.Investigating the contribution of CYP2J2 to ritonavir metabolism in vitro and in vivo.Cytochrome P450 2J2: distribution, function, regulation, genetic polymorphisms and clinical significance.Catalytic and Biocatalytic Iron Porphyrin Carbene Formation: Effects of Binding Mode, Carbene Substituent, Porphyrin Substituent, and Protein Axial Ligand.Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activityUnusual regioselectivity and active site topology of human cytochrome P450 2J2Roles of the epoxygenase CYP2J2 in the endothelium.Activity, inhibition, and induction of cytochrome P450 2J2 in adult human primary cardiomyocytes.Functional characterization of drug uptake and metabolism in the heart.Cytochrome P450 2U1, a very peculiar member of the human P450s family.Iron porphyrin carbenes as catalytic intermediates: structures, Mössbauer and NMR spectroscopic properties, and bondingComputational modelling of the binding of arachidonic acid to the human monooxygenase CYP2J2.Heme Modification Contributes to the Mechanism-Based Inactivation of Human Cytochrome P450 2J2 by Two Terminal Acetylenic Compounds.CYP2J2 - regulation, function and polymorphism.Role of Arginine 117 in Substrate Recognition by Human Cytochrome P450 2J2
P2860
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P2860
Selective, competitive and mechanism-based inhibitors of human cytochrome P450 2J2.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 10 April 2007
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Selective, competitive and mechanism-based inhibitors of human cytochrome P450 2J2.
@en
Selective, competitive and mechanism-based inhibitors of human cytochrome P450 2J2.
@nl
type
label
Selective, competitive and mechanism-based inhibitors of human cytochrome P450 2J2.
@en
Selective, competitive and mechanism-based inhibitors of human cytochrome P450 2J2.
@nl
prefLabel
Selective, competitive and mechanism-based inhibitors of human cytochrome P450 2J2.
@en
Selective, competitive and mechanism-based inhibitors of human cytochrome P450 2J2.
@nl
P2860
P50
P1476
Selective, competitive and mechanism-based inhibitors of human cytochrome P450 2J2
@en
P2093
Daniel Mansuy
Sylvie Dijols
P2860
P304
P356
10.1016/J.ABB.2007.03.028
P407
P577
2007-04-10T00:00:00Z