Inhibition of GSK3beta by indirubins restores HIF-1alpha accumulation under prolonged periods of hypoxia/anoxia.
about
Plk3 functions as an essential component of the hypoxia regulatory pathway by direct phosphorylation of HIF-1alphaHypoxia-Inducible Factors (HIFs) and Phosphorylation: Impact on Stability, Localization, and TransactivityRegulation of PTEN stability and activity by Plk3Gene expression profiling in equine polysaccharide storage myopathy revealed inflammation, glycogenesis inhibition, hypoxia and mitochondrial dysfunctions.Natural product-derived small molecule activators of hypoxia-inducible factor-1 (HIF-1)The tumour suppressor C/EBPδ inhibits FBXW7 expression and promotes mammary tumour metastasis.Celastrol stimulates hypoxia-inducible factor-1 activity in tumor cells by initiating the ROS/Akt/p70S6K signaling pathway and enhancing hypoxia-inducible factor-1α protein synthesis.Hypoxia-inducible factors modulate the stemness and malignancy of colon cancer cells by playing opposite roles in canonical Wnt signaling.Aldose reductase inhibition prevents hypoxia-induced increase in hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) by regulating 26 S proteasome-mediated protein degradation in human colon cancer cellsTemporal regulation of HIF-1 and NF-κB in hypoxic hepatocarcinoma cells.Small molecule-mediated up-regulation of microRNA targeting a key cell death modulator BNIP3 improves cardiac function following ischemic injury.GSK-3 and Wnt Signaling in Neurogenesis and Bipolar Disorder.The Effects of Indirubin-3'-Monoxime, A Novel AHR Ligand, on Stress and Toxicity-Related Gene/Protein Expression in Human U937 Cells Undergoing Differentiation and Activation.Signaling and apoptosis differences between severe hypoxia and desferoxamine treatment of human epithelial cells.The PI3K inhibitor LY294002 prevents p53 induction by DNA damage and attenuates chemotherapy-induced apoptosis.A targeted antioxidant reveals the importance of mitochondrial reactive oxygen species in the hypoxic signaling of HIF-1alpha.Hypoxia up-regulates hypoxia-inducible factor-1alpha transcription by involving phosphatidylinositol 3-kinase and nuclear factor kappaB in pulmonary artery smooth muscle cells.Hypoxia-Induced Signaling Promotes Prostate Cancer Progression: Exosomes Role as Messenger of Hypoxic Response in Tumor MicroenvironmentIncreased aerobic glycolysis is important for the motility of activated VSMC and inhibited by indirubin-3'-monoxime.Hypoxia regulates reactive oxygen species levels in SHG-44 glioma cellsStudies on the acetylation and NMR reassignment of indirubin derivatives.
P2860
Q24301526-6B8222C2-B5F4-4A58-B911-E77F10C1160EQ26768230-34BBB29B-0BC2-46DE-9BDC-4C5B5E721277Q28512686-BD90142D-7AA3-4946-9CE1-771A2EF5128CQ30490104-324764FD-46F8-454B-891D-5B649B4DF050Q34009713-CD6F7DE4-DD1E-4098-A9D9-F61099298202Q34479984-478751D4-30BF-44EA-AF76-0F867787805AQ34482963-BFC2AAA9-A4BC-4C41-9441-D8966C6F1104Q34513657-2561E433-7B68-4AAD-86A7-46E91F7336E7Q35085094-38B41C99-3CA0-4938-9EC0-2591F4578C93Q35832379-4471F87C-BEE8-4C16-8967-2A1D4732821DQ35968088-6CDE7085-BCA1-4D17-AD53-D167628C38B1Q37982704-37308560-44A8-43F6-B34E-FF308C2E1771Q39923913-84381C7C-D8DA-424D-8B16-90B5B32A2566Q39928753-4A887ACD-AEC1-4FE7-842A-D9EDB689F7FCQ40413928-455CADD5-2D23-4654-8777-3ED8B1A86F62Q40429133-E0E02EA3-A873-4272-A252-72AFE8CA3070Q40725245-B0A5871E-9706-484C-AA34-70C6EACD6359Q41913079-FD72DE36-2D23-4C22-8013-3C2C057E0D1BQ42426426-2AEB2622-42F2-4215-ADE0-3B3B1C366BA3Q42844795-417E2B6E-3B66-4ED9-B3DA-612F87FB3446Q43193520-B0941967-E9D6-4835-961F-4034AA0EB76F
P2860
Inhibition of GSK3beta by indirubins restores HIF-1alpha accumulation under prolonged periods of hypoxia/anoxia.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Inhibition of GSK3beta by indi ...... ged periods of hypoxia/anoxia.
@en
Inhibition of GSK3beta by indi ...... ged periods of hypoxia/anoxia.
@nl
type
label
Inhibition of GSK3beta by indi ...... ged periods of hypoxia/anoxia.
@en
Inhibition of GSK3beta by indi ...... ged periods of hypoxia/anoxia.
@nl
prefLabel
Inhibition of GSK3beta by indi ...... ged periods of hypoxia/anoxia.
@en
Inhibition of GSK3beta by indi ...... ged periods of hypoxia/anoxia.
@nl
P2093
P2860
P1433
P1476
Inhibition of GSK3beta by indi ...... ged periods of hypoxia/anoxia.
@en
P2093
Steffen E Schnitzer
Tobias Schmid
P2860
P304
P356
10.1016/J.FEBSLET.2004.12.023
P407
P577
2005-01-01T00:00:00Z