Botulinum neurotoxin serotype F: identification of substrate recognition requirements and development of inhibitors with low nanomolar affinity.
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SNAP-25 Substrate Peptide (Residues 180-183) Binds to but Bypasses Cleavage by Catalytically Active Clostridium botulinum Neurotoxin EMode of VAMP substrate recognition and inhibition of Clostridium botulinum neurotoxin FSecond generation steroidal 4-aminoquinolines are potent, dual-target inhibitors of the botulinum neurotoxin serotype A metalloprotease and P. falciparum malariaBasic tetrapeptides as potent intracellular inhibitors of type A botulinum neurotoxin protease activity.A yeast assay probes the interaction between botulinum neurotoxin serotype B and its SNARE substrate.Different substrate recognition requirements for cleavage of synaptobrevin-2 by Clostridium baratii and Clostridium botulinum type F neurotoxins.Cleavage of SNAP25 and its shorter versions by the protease domain of serotype A botulinum neurotoxin.Cargo-delivery platforms for targeted delivery of inhibitor cargos against botulism.Use of a recombinant fluorescent substrate with cleavage sites for all botulinum neurotoxins in high-throughput screening of natural product extracts for inhibitors of serotypes A, B, and E.Crystal structure of botulinum neurotoxin type G light chain: serotype divergence in substrate recognition.Toxins from bacteria.Molecular structures and functional relationships in clostridial neurotoxins.Clostridial neurotoxins: mechanism of SNARE cleavage and outlook on potential substrate specificity reengineering.Substrate recognition mechanism of VAMP/synaptobrevin-cleaving clostridial neurotoxins.Tyrosine phosphorylation of botulinum neurotoxin protease domainsAntimicrobial Peptides: New Recognition Molecules for Detecting Botulinum Toxins.Catalytic properties of botulinum neurotoxin subtypes A3 and A4.Molecular mechanisms of substrate recognition and specificity of botulinum neurotoxin serotype F.Mechanism of substrate recognition by botulinum neurotoxin serotype A.Unique substrate recognition by botulinum neurotoxins serotypes A and E.Targeted delivery into motor nerve terminals of inhibitors for SNARE-cleaving proteases via liposomes coupled to an atoxic botulinum neurotoxin.
P2860
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P2860
Botulinum neurotoxin serotype F: identification of substrate recognition requirements and development of inhibitors with low nanomolar affinity.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Botulinum neurotoxin serotype ...... s with low nanomolar affinity.
@en
Botulinum neurotoxin serotype ...... s with low nanomolar affinity.
@nl
type
label
Botulinum neurotoxin serotype ...... s with low nanomolar affinity.
@en
Botulinum neurotoxin serotype ...... s with low nanomolar affinity.
@nl
prefLabel
Botulinum neurotoxin serotype ...... s with low nanomolar affinity.
@en
Botulinum neurotoxin serotype ...... s with low nanomolar affinity.
@nl
P356
P1433
P1476
Botulinum neurotoxin serotype ...... s with low nanomolar affinity.
@en
P2093
James J Schmidt
Robert G Stafford
P304
P356
10.1021/BI0477642
P407
P577
2005-03-01T00:00:00Z