Depletion of CD8+ cells in sooty mangabey monkeys naturally infected with simian immunodeficiency virus reveals limited role for immune control of virus replication in a natural host species.
about
Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hostsNonpathogenic simian immunodeficiency virus infectionsMultifunctional double-negative T cells in sooty mangabeys mediate T-helper functions irrespective of SIV infectionInhibition of adaptive immune responses leads to a fatal clinical outcome in SIV-infected pigtailed macaques but not vervet African green monkeys.CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells.In vivo CD8+ T-cell suppression of siv viremia is not mediated by CTL clearance of productively infected cells.Mosaic HIV-1 vaccines expand the breadth and depth of cellular immune responses in rhesus monkeys.Acute mucosal pathogenesis of feline immunodeficiency virus is independent of viral dose in vaginally infected cats.Suppression of adaptive immune responses during primary SIV infection of sabaeus African green monkeys delays partial containment of viremia but does not induce disease.A five-year longitudinal analysis of sooty mangabeys naturally infected with simian immunodeficiency virus reveals a slow but progressive decline in CD4+ T-cell count whose magnitude is not predicted by viral load or immune activationExperimental depletion of CD8+ cells in acutely SIVagm-infected African Green Monkeys results in increased viral replication.Lineage-specific T-cell reconstitution following in vivo CD4+ and CD8+ lymphocyte depletion in nonhuman primates.Lack of clinical AIDS in SIV-infected sooty mangabeys with significant CD4+ T cell loss is associated with double-negative T cells.CD8+ cell depletion accelerates HIV-1 immunopathology in humanized mice.Immunity in natural SIV infections.CCR5 blockade is well tolerated and induces changes in the tissue distribution of CCR5+ and CD25+ T cells in healthy, SIV-uninfected rhesus macaquesMucosal simian immunodeficiency virus transmission in African green monkeys: susceptibility to infection is proportional to target cell availability at mucosal sitesUnderstanding the benign nature of SIV infection in natural hosts.Differential infection patterns of CD4+ T cells and lymphoid tissue viral burden distinguish progressive and nonprogressive lentiviral infections.Distinct evolutionary pressures underlie diversity in simian immunodeficiency virus and human immunodeficiency virus lineages.Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeysThe quality of chimpanzee T-cell activation and simian immunodeficiency virus/human immunodeficiency virus susceptibility achieved via antibody-mediated T-cell receptor/CD3 stimulation is a function of the anti-CD3 antibody isotype.Simian immunodeficiency virus (SIV)-specific CD8+ T-cell responses in vervet African green monkeys chronically infected with SIVagm.Human immunodeficiency virus-specific gamma interferon enzyme-linked immunospot assay responses targeting specific regions of the proteome during primary subtype C infection are poor predictors of the course of viremia and set pointImmunobiology of human cytomegalovirus: from bench to bedside.Bone marrow-based homeostatic proliferation of mature T cells in nonhuman primates: implications for AIDS pathogenesis.Immune activation and collateral damage in AIDS pathogenesis.CD4 downregulation by memory CD4+ T cells in vivo renders African green monkeys resistant to progressive SIVagm infection.Differential pathogenicity of SHIV infection in pig-tailed and rhesus macaquesViral sequence diversity: challenges for AIDS vaccine designs.Effect of B-cell depletion on viral replication and clinical outcome of simian immunodeficiency virus infection in a natural host.T cell susceptibility to HIV influences outcome of opportunistic infections.AIDS pathogenesis: a tale of two monkeys.Where the wild things are: pathogenesis of SIV infection in African nonhuman primate hosts.Biology and pathogenesis of cytomegalovirus in periodontal disease.The Knife's Edge of Tolerance: Inducing Stable Multilineage Mixed Chimerism but With a Significant Risk of CMV Reactivation and Disease in Rhesus Macaques.The well-tempered SIV infection: Pathogenesis of SIV infection in natural hosts in the wild, with emphasis on virus transmission and early events post-infection that may contribute to protection from disease progression.Lessons on Non-Progression of HIV Disease from Monkeys.CD8+ cell depletion of SHIV89.6P-infected macaques induces CD4+ T cell proliferation that contributes to increased viral loads.Control of HIV-1 Pathogenesis in Viremic Nonprogressors Is Independent of Gag-Specific Cytotoxic T Lymphocyte Responses.
P2860
Q22251065-14DEE632-2CFB-4780-A40D-FA7112EF26C4Q27004065-194CC506-B0E5-4C2A-A2F7-45405A4FF995Q27334516-B6903EC7-D4B0-4EBC-94C3-9E7CB2AE9C1FQ33518502-117F1576-E477-48E6-97E3-00EB140530AAQ33618007-35320764-9CA4-439F-AA22-571844FCDF15Q33618013-E88F5571-D7AF-431B-AF7D-E6DC3CF2B9B9Q33712578-6523638E-07E7-4D33-8960-B2B080CE16CFQ33715758-AB9B989E-40F2-40B9-8857-7C500F994789Q33806000-59E8B2A2-7131-41DF-80CD-221722A9F748Q33877335-5056CE97-B7F0-4CFA-A739-72024FAC9B4CQ33888012-FD8D0FCB-B724-4687-BCEB-39F745FFF211Q34052601-9BD62D96-44AE-4CA4-8199-A509E974E59EQ34164295-0365D4DD-2328-40E4-9B7C-AB825592EBABQ34433569-4E1A5B2F-ACCD-46B4-A7AF-474ACDFB00D6Q34602157-C523D5B1-8A59-492C-B5F1-4D33BFE71F10Q35693333-91C8CB08-29D2-4568-B475-FD163DC8BC04Q35868061-097A5345-9BD4-47A5-B929-1FC7EDA87810Q36099429-F3346A4B-D29F-424B-AA6E-31F77696145EQ36410144-84B91D0E-05D4-4537-90A9-B8573335B44BQ36414547-13C8C472-B30D-4C75-B6BC-24E74E0A45EBQ36667267-CDAB67E4-AF44-481F-8C43-5180AE06E4DBQ36933992-736A8098-9539-447C-8D09-1DDC2CD8ED51Q36974698-16807D2F-593F-4D04-B901-F5254CC49D7AQ37033201-C0DE1D6B-FE83-4D3D-A8C6-C3A912DE4F85Q37050965-0AE34746-9458-4198-8481-1A45F7B99523Q37066240-49CBF7BB-AD9F-4AD0-8EF1-5726E97576D3Q37199493-BBBE42D0-F48C-45D3-934D-80CD63F83A03Q37295552-719C79F4-0DBE-46A7-B67E-589F85A29424Q37309980-B593CC2B-3D13-4F84-A2A9-AC1A5E96EC54Q37316023-7B02F942-B238-42E5-950E-2FC8FF00598AQ37365356-AE275670-309B-4C2F-ABD5-05EA9DABC8E2Q37382387-10FDFFD0-C749-41C3-B24A-03641CDC8BF4Q37383585-C465BF82-7357-4184-9823-5CA08E7468EEQ37738146-5621C52A-0DF3-40F6-B730-C91AA02B61C8Q38169797-CFEC0A76-9BCD-430A-BB8D-E8AFC5BC35C8Q40584637-27BDD448-482B-4EFA-A62C-BBCBDF749D67Q40619853-A49D15DA-A1EC-4AF6-B926-AB1C2270BB14Q41214512-7D2B6F3B-E574-499A-931F-0092D0AEC36FQ42577154-7CAD35F8-84B4-437E-A811-C6A026D09999Q52625002-D9522310-3C27-4999-A576-65CF330C375A
P2860
Depletion of CD8+ cells in sooty mangabey monkeys naturally infected with simian immunodeficiency virus reveals limited role for immune control of virus replication in a natural host species.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Depletion of CD8+ cells in soo ...... ion in a natural host species.
@en
Depletion of CD8+ cells in soo ...... ion in a natural host species.
@nl
type
label
Depletion of CD8+ cells in soo ...... ion in a natural host species.
@en
Depletion of CD8+ cells in soo ...... ion in a natural host species.
@nl
prefLabel
Depletion of CD8+ cells in soo ...... ion in a natural host species.
@en
Depletion of CD8+ cells in soo ...... ion in a natural host species.
@nl
P2093
P1476
Depletion of CD8+ cells in soo ...... ion in a natural host species.
@en
P2093
Ashley P Barry
Beth Sumpter
Guido Silvestri
Harold M McClure
Jeffrey T Safrit
Mark B Feinberg
Natalia Kozyr
Silvija I Staprans
P304
P356
10.4049/JIMMUNOL.178.12.8002
P407
P577
2007-06-01T00:00:00Z