Lethal cutaneous disease in transgenic mice conditionally expressing type I human T cell leukemia virus Tax.
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The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1HTLV-1 Tax Functions as a Ubiquitin E3 Ligase for Direct IKK Activation via Synthesis of Mixed-Linkage Polyubiquitin ChainsT-cell activation promotes tumorigenesis in inflammation-associated cancer.Immune activation induces immortalization of HTLV-1 LTR-Tax transgenic CD4+ T cellsHTLV-1 tax stabilizes MCL-1 via TRAF6-dependent K63-linked polyubiquitination to promote cell survival and transformationRole of post-translational modifications of HTLV-1 Tax in NF-κB activation.Human T cell leukemia virus type 1 Tax inhibits innate antiviral signaling via NF-kappaB-dependent induction of SOCS1.Human T-cell lymphotropic virus: a model of NF-κB-associated tumorigenesisMouse models of human T lymphotropic virus type-1-associated adult T-cell leukemia/lymphoma.Human T Lymphotropic Virus Type 1 (HTLV-1): Molecular Biology and Oncogenesis.A Transgenic Drosophila melanogaster Model To Study Human T-Lymphotropic Virus Oncoprotein Tax-1-Driven Transformation In Vivo.The tumor suppressor gene WWOX links the canonical and noncanonical NF-κB pathways in HTLV-I Tax-mediated tumorigenesisInducible nitric oxide synthase mediates DNA double strand breaks in Human T-Cell Leukemia Virus Type 1-induced leukemia/lymphoma.What we are learning on HTLV-1 pathogenesis from animal models.Akt Pathway Activation by Human T-cell Leukemia Virus Type 1 Tax Oncoprotein.Imaging spontaneous tumorigenesis: inflammation precedes development of peripheral NK tumors.PDLIM2 suppresses human T-cell leukemia virus type I Tax-mediated tumorigenesis by targeting Tax into the nuclear matrix for proteasomal degradationHuman T-cell leukemia virus type I-mediated repression of PDZ-LIM domain-containing protein 2 involves DNA methylation but independent of the viral oncoprotein tax.NF-κB as a target for oncogenic viruses.Bromodomain and extraterminal (BET) protein inhibition suppresses human T cell leukemia virus 1 (HTLV-1) Tax protein-mediated tumorigenesis by inhibiting nuclear factor κB (NF-κB) signalingMolecular mechanisms of HTLV-1 infection and pathogenesis.Targeting HTLV-1 activation of NFκB in mouse models and ATLL patients.Animal models on HTLV-1 and related viruses: what did we learn?A critical role for IL-17RB signaling in HTLV-1 tax-induced NF-κB activation and T-cell transformation.Molecular determinants of PDLIM2 in suppressing HTLV-I Tax-mediated tumorigenesis.HTLV-1 bZIP factor suppresses TDP1 expression through inhibition of NRF-1 in adult T-cell leukemia.Conference highlights of the 16th International Conference on Human Retrovirology: HTLV and related retroviruses, 26-30 June 2013, Montreal, Canada.Mouse Models That Enhanced Our Understanding of Adult T Cell Leukemia.
P2860
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P2860
Lethal cutaneous disease in transgenic mice conditionally expressing type I human T cell leukemia virus Tax.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Lethal cutaneous disease in tr ...... man T cell leukemia virus Tax.
@en
Lethal cutaneous disease in tr ...... man T cell leukemia virus Tax.
@nl
type
label
Lethal cutaneous disease in tr ...... man T cell leukemia virus Tax.
@en
Lethal cutaneous disease in tr ...... man T cell leukemia virus Tax.
@nl
prefLabel
Lethal cutaneous disease in tr ...... man T cell leukemia virus Tax.
@en
Lethal cutaneous disease in tr ...... man T cell leukemia virus Tax.
@nl
P2093
P2860
P356
P1476
Lethal cutaneous disease in tr ...... man T cell leukemia virus Tax.
@en
P2093
Bobby Benitez
Dean W Felsher
Hakju Kwon
Jan Bohuslav
Louise Ogle
Mauricio Montano
Warner C Greene
P2860
P304
35713-35722
P356
10.1074/JBC.M504848200
P407
P577
2005-08-16T00:00:00Z