Endothelin-1 protects ovarian carcinoma cells against paclitaxel-induced apoptosis: requirement for Akt activation.
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Protein kinase B/Akt binds and phosphorylates PED/PEA-15, stabilizing its antiapoptotic actionEndothelin receptors as novel targets in tumor therapyedn1 and hand2 Interact in early regulation of pharyngeal arch outgrowth during zebrafish developmentThe endothelin axis: emerging role in cancerEndothelin-1 promotes survival and chemoresistance in chronic lymphocytic leukemia B cells through ETA receptorEndothelin-1 inhibits apoptosis of pulmonary arterial smooth muscle in the neonatal ratClinical pharmacology of an atrasentan and docetaxel regimen in men with hormone-refractory prostate cancerElevation of circulating big endothelin-1: an independent prognostic factor for tumor recurrence and survival in patients with esophageal squamous cell carcinoma.Effects of silencing endothelin-1 on invasion and vascular formation in lung cancer.COOPERATIVE GROUP TRIALS - SOUTHWEST ONCOLOGY GROUP (SWOG) INNOVATIONS IN ADVANCED PROSTATE CANCER.Role of the endothelin axis in astrocyte- and endothelial cell-mediated chemoprotection of cancer cells.Endothelin-1 inhibits apoptosis in prostate cancerEndothelin-1 enhances oxidative stress, cell proliferation and reduces apoptosis in human umbilical vein endothelial cells: role of ETB receptor, NADPH oxidase and caveolin-1Cre recombinase-regulated Endothelin1 transgenic mouse lines: novel tools for analysis of embryonic and adult disorders.Endothelin receptor blockade inhibits molecular effectors of Kaposi's sarcoma cell invasion and tumor growth in vivoDeciphering mechanisms of drug sensitivity and resistance to Selective Inhibitor of Nuclear Export (SINE) compoundsAtrasentan: targeting the endothelin axis in prostate cancer.A causal role for endothelin-1 in the pathogenesis of osteoblastic bone metastases.The Development of an Angiogenic Protein "Signature" in Ovarian Cancer Ascites as a Tool for Biologic and Prognostic Profiling.FOXO1 mediates the autocrine effect of endothelin-1 on endothelial cell survival.Specific inhibition of the endothelin A receptor with ZD4054: clinical and pre-clinical evidence.Expression of endothelin-A-receptor predicts unfavourable response to neoadjuvant chemotherapy in locally advanced breast cancer.Epithelial-mesenchymal transition in ovarian cancer progression: a crucial role for the endothelin axis.Endothelin-1 enriched tumor phenotype predicts breast cancer recurrence.Endothelin receptor antagonists in cancer therapy.Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis.The independent, unfavorable prognostic factors endothelin A receptor and chemokine receptor 4 have a close relationship in promoting the motility of nasopharyngeal carcinoma cells via the activation of AKT and MAPK pathways.Targeting the endothelin system: novel therapeutic options in gynecological, urological and breast cancers.The importance of endothelin axis in initiation, progression, and therapy of ovarian cancer.Molecular targeted therapy in ovarian cancer: what is on the horizon?Endothelin-1 (ET-1) induces resistance to bortezomib in human multiple myeloma cells via a pathway involving the ETB receptor and upregulation of proteasomal activity.ROCK cooperated with ET-1 to induce epithelial to mesenchymal transition through SLUG in human ovarian cancer cells.Expression patterns of endothelin-1 and its receptors in colorectal cancer.BMP-4 expression has prognostic significance in advanced serous ovarian carcinoma and is affected by cisplatin in OVCAR-3 cells.Beta-arrestin-1 mediates the endothelin-1-induced activation of Akt and integrin-linked kinase.Combination therapy of zibotentan with cisplatinum and paclitaxel is an effective regimen for epithelial ovarian cancer.Simultaneous inhibition of the mitogen-activated protein kinase kinase and phosphatidylinositol 3'-kinase pathways enhances sensitivity to paclitaxel in ovarian carcinoma.Effect of endothelin-1 in esophageal squamous cell carcinoma invasion and its correlation with cathepsin B.Lonidamine causes inhibition of angiogenesis-related endothelial cell functions.Endothelin-1-induced prostaglandin E2-EP2, EP4 signaling regulates vascular endothelial growth factor production and ovarian carcinoma cell invasion.
P2860
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P2860
Endothelin-1 protects ovarian carcinoma cells against paclitaxel-induced apoptosis: requirement for Akt activation.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Endothelin-1 protects ovarian ...... equirement for Akt activation.
@en
Endothelin-1 protects ovarian ...... equirement for Akt activation.
@nl
type
label
Endothelin-1 protects ovarian ...... equirement for Akt activation.
@en
Endothelin-1 protects ovarian ...... equirement for Akt activation.
@nl
prefLabel
Endothelin-1 protects ovarian ...... equirement for Akt activation.
@en
Endothelin-1 protects ovarian ...... equirement for Akt activation.
@nl
P2093
P50
P356
P1476
Endothelin-1 protects ovarian ...... equirement for Akt activation.
@en
P2093
Debora Salani
Francesca Spinella
Marco Varmi
P304
P356
10.1124/MOL.61.3.524
P50
P577
2002-03-01T00:00:00Z