Nonsense-mediated mRNA decay occurs during eIF4F-dependent translation in human cells. - Wikidata - awgldk - TriplyDB

Nonsense-mediated mRNA decay occurs during eIF4F-dependent translation in human cells.

Nonsense-mediated mRNA decay occurs during eIF4F-dependent translation in human cells.

http://www.wikidata.org/entity/Q45931847

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mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3 Nonsense-mediated mRNA decay: novel mechanistic insights and biological impact The dharma of nonsense-mediated mRNA decay in mammalian cells Nonsense-mediated mRNA decay in humans at a glance Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the Story Organizing principles of mammalian nonsense-mediated mRNA decay Eukaryotic initiation factor 4G suppresses nonsense-mediated mRNA decay by two genetically separable mechanisms The RNA helicase Ddx5/p68 binds to hUpf3 and enhances NMD of Ddx17/p72 and Smg5 mRNA Modulation of nonsense mediated decay by rapamycin The mRNP remodeling mediated by UPF1 promotes rapid degradation of replication-dependent histone mRNA.A post-translational regulatory switch on UPF1 controls targeted mRNA degradation The interaction of cytoplasmic poly(A)-binding protein with eukaryotic initiation factor 4G suppresses nonsense-mediated mRNA decay.eIF4AIII enhances translation of nuclear cap-binding complex-bound mRNAs by promoting disruption of secondary structures in 5'UTR.Nonsense-mediated mRNA decay immunity can help identify human polycistronic transcripts hnRNP F complexes with tristetraprolin and stimulates ARE-mRNA decay.NMD: At the crossroads between translation termination and ribosome recycling.Control of mRNA Stability in Fungi by NMD, EJC and CBC Factors Through 3'UTR Introns Hyperphosphorylation amplifies UPF1 activity to resolve stalls in nonsense-mediated mRNA decay.Therapeutics based on stop codon readthrough.Translating DRiPs: MHC class I immunosurveillance of pathogens and tumors.Selective localization of arc mRNA in dendrites involves activity- and translation-dependent mRNA degradation.Cap-binding complex (CBC).Regulation of natural mRNAs by the nonsense-mediated mRNA decay pathway.Mechanism, factors, and physiological role of nonsense-mediated mRNA decay.Nonsense-mediated mRNA decay: an intricate machinery that shapes transcriptomes.NMD monitors translational fidelity 24/7.Translation initiation mediated by nuclear cap-binding protein complex.Nonsense-mediated mRNA decay at the crossroads of many cellular pathways Nonsense-mediated decay of alternative precursor mRNA splicing variants is a major determinant of the Arabidopsis steady state transcriptome.Making sense of nonsense.Identifying Cellular Nonsense-Mediated mRNA Decay (NMD) Targets: Immunoprecipitation of Phosphorylated UPF1 Followed by RNA Sequencing (p-UPF1 RIP-Seq).

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P2860

Nonsense-mediated mRNA decay occurs during eIF4F-dependent translation in human cells.

http://www.wikidata.org/entity/Q45931847

description

2013 nî lūn-bûn

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2013年の論文

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2013年学术文章

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2013年学术文章

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name

Nonsense-mediated mRNA decay occurs during eIF4F-dependent translation in human cells.

@en

Nonsense-mediated mRNA decay occurs during eIF4F-dependent translation in human cells.

@nl

type

label

Nonsense-mediated mRNA decay occurs during eIF4F-dependent translation in human cells.

@en

Nonsense-mediated mRNA decay occurs during eIF4F-dependent translation in human cells.

@nl

prefLabel

Nonsense-mediated mRNA decay occurs during eIF4F-dependent translation in human cells.

@en

Nonsense-mediated mRNA decay occurs during eIF4F-dependent translation in human cells.

@nl

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P1433

Nature Structural & Molecular Biology

P1476

Nonsense-mediated mRNA decay occurs during eIF4F-dependent translation in human cells.

@en

P2093

Jens Lykke-Andersen

http://www.w3.org/2001/XMLSchema#string

Sébastien Durand

http://www.w3.org/2001/XMLSchema#string

P2860

Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon

Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay

Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex

Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1

Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20

Characterization of human Smg5/7a: a protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1.

Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7

The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus

eIF4G is required for the pioneer round of translation in mammalian cells

SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan

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10.1038/NSMB.2575

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6

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20

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1034591377

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