Isoform-specific effects of apolipoproteins E2, E3, and E4 on cerebral capillary sequestration and blood-brain barrier transport of circulating Alzheimer's amyloid beta.
about
Impaired vascular-mediated clearance of brain amyloid beta in Alzheimer's disease: the role, regulation and restoration of LRP1Apolipoprotein E isoform-specific effects on lipoprotein receptor processing.Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous systemGenetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathiesNeurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease.Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrierEndothelial protein C receptor-assisted transport of activated protein C across the mouse blood-brain barrierOxidative stress increases blood-brain barrier permeability and induces alterations in occludin during hypoxia-reoxygenation.Low-density lipoprotein receptor-related protein-1: a serial clearance homeostatic mechanism controlling Alzheimer's amyloid β-peptide elimination from the brainThe role of apolipoprotein E in Alzheimer's disease.CD45 deficiency drives amyloid-β peptide oligomers and neuronal loss in Alzheimer's disease miceClearance of amyloid-beta peptide across the blood-brain barrier: implication for therapies in Alzheimer's disease.Hypertension and cognitive functionNeurovascular defects and faulty amyloid-β vascular clearance in Alzheimer's diseaseLow-density lipoprotein receptor-related protein 1: a physiological Aβ homeostatic mechanism with multiple therapeutic opportunities.Apolipoprotein E does not cross the blood-cerebrospinal fluid barrier, as revealed by an improved technique for sampling CSF from miceBlood-brain barrier breakdown as a therapeutic target in traumatic brain injury.USE OF FUSED CIRCULATIONS TO INVESTIGATE THE ROLE OF APOLIPOPROTEIN E AS AMYLOID CATALYST AND PERIPHERAL SINK IN ALZHEIMER'S DISEASE.Blood-brain barrier dysfunction as a cause and consequence of Alzheimer's disease.Biophysical analysis of progressive C-terminal truncations of human apolipoprotein E4: insights into secondary structure and unfolding properties.The role of the cell surface LRP and soluble LRP in blood-brain barrier Abeta clearance in Alzheimer's disease.In vivo Differential Brain Clearance and Catabolism of Monomeric and Oligomeric Alzheimer's Aβ proteinHuman blood-brain barrier receptors for Alzheimer's amyloid-beta 1- 40. Asymmetrical binding, endocytosis, and transcytosis at the apical side of brain microvascular endothelial cell monolayer.The blood-brain barrier in neurodegenerative disease: a rhetorical perspective.The systemic iron-regulatory proteins hepcidin and ferroportin are reduced in the brain in Alzheimer's disease.Brain capillary endothelium and choroid plexus epithelium regulate transport of transferrin-bound and free iron into the rat brain.The choroid plexus removes beta-amyloid from brain cerebrospinal fluid.Current therapeutic targets for the treatment of Alzheimer's disease.Cerebral amyloid angiopathy: a systematic reviewDrug delivery to the brain in Alzheimer's disease: consideration of the blood-brain barrier.Amyloid beta: structure, biology and structure-based therapeutic development.Permeability of the blood-brain barrier to a rhenacarborane.apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain.Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes.
P2860
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P2860
Isoform-specific effects of apolipoproteins E2, E3, and E4 on cerebral capillary sequestration and blood-brain barrier transport of circulating Alzheimer's amyloid beta.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh-hant
name
Isoform-specific effects of ap ...... ting Alzheimer's amyloid beta.
@en
Isoform-specific effects of ap ...... ting Alzheimer's amyloid beta.
@nl
type
label
Isoform-specific effects of ap ...... ting Alzheimer's amyloid beta.
@en
Isoform-specific effects of ap ...... ting Alzheimer's amyloid beta.
@nl
prefLabel
Isoform-specific effects of ap ...... ting Alzheimer's amyloid beta.
@en
Isoform-specific effects of ap ...... ting Alzheimer's amyloid beta.
@nl
P2093
P1476
Isoform-specific effects of ap ...... ating Alzheimer's amyloid beta
@en
P2093
B Frangione
B V Zlokovic
C L Martel
E Matsubara
J B Mackic
J G McComb
S Governale
P304
P356
10.1046/J.1471-4159.1997.69051995.X
P407
P577
1997-11-01T00:00:00Z