CD45 deficiency drives amyloid-β peptide oligomers and neuronal loss in Alzheimer's disease mice - Wikidata - awgldk - TriplyDB

CD45 deficiency drives amyloid-β peptide oligomers and neuronal loss in Alzheimer's disease mice

CD45 deficiency drives amyloid-β peptide oligomers and neuronal loss in Alzheimer's disease mice

http://www.wikidata.org/entity/Q34744169

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Protein phosphatases and Alzheimer's disease Alzheimer's disease: new data highlight nonneuronal cell types and the necessity for presymptomatic prevention strategies Innate immunity in Alzheimer's disease: a complex affair Interactions between inflammation, sex steroids, and Alzheimer's disease risk factors Ferulic acid is a nutraceutical β-secretase modulator that improves behavioral impairment and alzheimer-like pathology in transgenic mice In vivo inhibition of miR-155 significantly alters post-stroke inflammatory response CR1 and the "vanishing amyloid" hypothesis of Alzheimer's disease.Evaluation of neural damage in Duchenne muscular dystrophy patients.Baicalein reduces β-amyloid and promotes nonamyloidogenic amyloid precursor protein processing in an Alzheimer's disease transgenic mouse model Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology.Swedish mutant APP-based BACE1 binding site peptide reduces APP β-cleavage and cerebral Aβ levels in Alzheimer's mice.Tannic acid is a natural β-secretase inhibitor that prevents cognitive impairment and mitigates Alzheimer-like pathology in transgenic mice.Soluble intracellular adhesion molecule-1 secreted by human umbilical cord blood-derived mesenchymal stem cell reduces amyloid-β plaques The immunology of neurodegeneration.Minocycline corrects early, pre-plaque neuroinflammation and inhibits BACE-1 in a transgenic model of Alzheimer's disease-like amyloid pathology.Amyloid deposition and advanced age fails to induce Alzheimer's type progression in a double knock-in mouse model Microglia in Alzheimer's Disease: It's All About Context.Effects of human intravenous immunoglobulin on amyloid pathology and neuroinflammation in a mouse model of Alzheimer's disease.Soluble amyloid precursor protein alpha inhibits tau phosphorylation through modulation of GSK3β signaling pathway.Soluble amyloid precursor protein-α modulates β-secretase activity and amyloid-β generation.Toll-like receptor 4 stimulation with the detoxified ligand monophosphoryl lipid A improves Alzheimer's disease-related pathology.α-Synuclein oligomers and clinical implications for Parkinson disease.GFAP expression and social deficits in transgenic mice overexpressing human sAPPα.The role of the innate immune system in Alzheimer's disease and frontotemporal lobar degeneration: an eye on microglia.Mycoplasma hyorhinis markedly degrades β-amyloid peptides in vitro and ex vivo: a novel biological approach for treating Alzheimer's disease?Clearance of amyloid-β peptides by microglia and macrophages: the issue of what, when and where.A matter of life, death and diseases: mitochondria from a proteomic perspective.The neglected role of histamine in Alzheimer's disease.Modulation of inflammation in transgenic models of Alzheimer's disease Environmental factors in the development and progression of late-onset Alzheimer's disease.Microglial Aβ receptors in Alzheimer's disease.Targeting microglia for the treatment of Alzheimer's disease.Innate immunity in Alzheimer's disease.LISPRO mitigates β-amyloid and associated pathologies in Alzheimer's mice.The protein-tyrosine phosphatase DEP-1 promotes migration and phagocytic activity of microglial cells in part through negative regulation of fyn tyrosine kinase.Exosomes from NSC-34 Cells Transfected with hSOD1-G93A Are Enriched in miR-124 and Drive Alterations in Microglia Phenotype.Efficacy of a therapeutic vaccine using mutated β-amyloid sensitized dendritic cells in Alzheimer's mice.Animal Models of Alzheimer's Disease: Utilization of Transgenic Alzheimer's Disease Models in Studies of Amyloid Beta Clearance.Diosmin reduces cerebral Aβ levels, tau hyperphosphorylation, neuroinflammation, and cognitive impairment in the 3xTg-AD mice.

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CD45 deficiency drives amyloid-β peptide oligomers and neuronal loss in Alzheimer's disease mice

http://www.wikidata.org/entity/Q34744169

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

CD45 deficiency drives amyloid ...... ss in Alzheimer's disease mice

@ast

CD45 deficiency drives amyloid ...... ss in Alzheimer's disease mice

@en

CD45 deficiency drives amyloid ...... ss in Alzheimer's disease mice

@nl

type

label

CD45 deficiency drives amyloid ...... ss in Alzheimer's disease mice

@ast

CD45 deficiency drives amyloid ...... ss in Alzheimer's disease mice

@en

CD45 deficiency drives amyloid ...... ss in Alzheimer's disease mice

@nl

prefLabel

CD45 deficiency drives amyloid ...... ss in Alzheimer's disease mice

@ast

CD45 deficiency drives amyloid ...... ss in Alzheimer's disease mice

@en

CD45 deficiency drives amyloid ...... ss in Alzheimer's disease mice

@nl

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JNEUROSCI.3268-10.2011

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Journal of Neuroscience

P1476

CD45 deficiency drives amyloid ...... ss in Alzheimer's disease mice

@en

P2093

Amanda Ruscin

http://www.w3.org/2001/XMLSchema#string

Brian Giunta

http://www.w3.org/2001/XMLSchema#string

Carmelina Gemma

http://www.w3.org/2001/XMLSchema#string

Charles G Glabe

http://www.w3.org/2001/XMLSchema#string

Demian Obregon

http://www.w3.org/2001/XMLSchema#string

Huayan Hou

http://www.w3.org/2001/XMLSchema#string

Jared Ehrhart

http://www.w3.org/2001/XMLSchema#string

Jingji Jin

http://www.w3.org/2001/XMLSchema#string

Jun Tan

http://www.w3.org/2001/XMLSchema#string

Kavon Rezai-Zadeh

http://www.w3.org/2001/XMLSchema#string

P2860

Regulation of integrin-mediated T cell adhesion by the transmembrane protein tyrosine phosphatase CD45

CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling

Actin-binding proteins coronin-1a and IBA-1 are effective microglial markers for immunohistochemistry

CD45 regulates Src family member kinase activity associated with macrophage integrin-mediated adhesion

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

The microglial "activation" continuum: from innate to adaptive responses

Alzheimer's disease: genes, proteins, and therapy

Inflammation and Alzheimer's disease

Neuropathologic changes in Alzheimer's disease

Evidence that production and release of amyloid beta-protein involves the endocytic pathway

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1355-1365

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scholarly article

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10.1523/JNEUROSCI.3268-10.2011

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4

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31

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2011-01-01T00:00:00Z

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21273420

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Alzheimer's disease

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3068193

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