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Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's diseaseDysregulation of the autophagy-endolysosomal system in amyotrophic lateral sclerosis and related motor neuron diseasesGuidelines for the use and interpretation of assays for monitoring autophagyGenome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WACPHF23 (plant homeodomain finger protein 23) negatively regulates cell autophagy by promoting ubiquitination and degradation of E3 ligase LRSAM1Laforin, the most common protein mutated in Lafora disease, regulates autophagyPI(5)P regulates autophagosome biogenesisInterplay of LRRK2 with chaperone-mediated autophagyAutophagic substrate clearance requires activity of the syntaxin-5 SNARE complexLysosomal transmembrane protein LAPTM4B promotes autophagy and tolerance to metabolic stress in cancer cellsAkt and autophagy cooperate to promote survival of drug-resistant gliomaEthanol-induced oxidant stress modulates hepatic autophagy and proteasome activityThe dynamic behavior of storage organelles in developing cereal seeds and its impact on the production of recombinant proteinsAutophagy modulation as a potential therapeutic target for diverse diseasesTestosterone plus low-intensity physical training in late life improves functional performance, skeletal muscle mitochondrial biogenesis, and mitochondrial quality control in male miceLoss of ALS2/Alsin exacerbates motor dysfunction in a SOD1-expressing mouse ALS model by disturbing endolysosomal traffickingNADPH oxidase promotes Parkinsonian phenotypes by impairing autophagic flux in an mTORC1-independent fashion in a cellular model of Parkinson's diseaseMevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for p53Macroautophagy is defective in mucolipin-1-deficient mouse neuronsInhibition of mTOR-dependent autophagy sensitizes leukemic cells to cytarabine-induced apoptotic deathTetra-O-Methyl Nordihydroguaiaretic Acid Broadly Suppresses Cancer Metabolism and Synergistically Induces Strong Anticancer Activity in Combination with Etoposide, Rapamycin and UCN-01Decreased mitochondrial DNA copy number in the hippocampus and peripheral blood during opiate addiction is mediated by autophagy and can be salvaged by melatoninReduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1Methods in mammalian autophagy researchPlasma membrane contributes to the formation of pre-autophagosomal structuresAutophagy gone awry in neurodegenerative diseases(Pro)renin receptor regulates autophagy and apoptosis in podocytes exposed to high glucose.Deletion of the huntingtin polyglutamine stretch enhances neuronal autophagy and longevity in mice.Mitochondrial metabolism in Parkinson's disease impairs quality control autophagy by hampering microtubule-dependent traffic.PICALM modulates autophagy activity and tau accumulation.Transcriptional regulation of Annexin A2 promotes starvation-induced autophagyLoss of function of the ALS protein SigR1 leads to ER pathology associated with defective autophagy and lipid raft disturbancesThe Dynamics and Turnover of Tau Aggregates in Cultured Cells: INSIGHTS INTO THERAPIES FOR TAUOPATHIES.Retrograde transport of TrkB-containing autophagosomes via the adaptor AP-2 mediates neuronal complexity and prevents neurodegenerationPrenatal alcohol exposure impairs autophagy in neonatal brain cortical microvessels.Phase II study of sorafenib in patients with relapsed or refractory lymphoma.Autophagy activation reduces renal tubular injury induced by urinary proteins.ROS-mediated autophagy induced by dysregulation of lipid metabolism plays a protective role in colorectal cancer cells treated with gambogic acid.Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP diseaseMutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS).
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
In search of an "autophagomometer".
@en
In search of an "autophagomometer".
@nl
type
label
In search of an "autophagomometer".
@en
In search of an "autophagomometer".
@nl
prefLabel
In search of an "autophagomometer".
@en
In search of an "autophagomometer".
@nl
P2093
P50
P356
P1433
P1476
In search of an "autophagomometer".
@en
P2093
Brinda Ravikumar
David C Rubinsztein
Susmita Kaushik
P304
P356
10.4161/AUTO.5.5.8823
P577
2009-07-23T00:00:00Z