about
Akt and mTOR in B Cell Activation and DifferentiationNaturally secreted amyloid-beta increases mammalian target of rapamycin (mTOR) activity via a PRAS40-mediated mechanismRole of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacksTargeting mTOR for the treatment of AML. New agents and new directionsMammalian target of rapamycin (mTOR): conducting the cellular signaling symphonyRegulation of adipocyte autophagy--the potential anti-obesity mechanism of high density lipoprotein and ApolipoproteinA-IAutophagy and cancer cell metabolismSMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planariansmTOR-independent 4E-BP1 phosphorylation is associated with cancer resistance to mTOR kinase inhibitors.mTOR inhibitors in cancer therapyRole of the mammalian target of rapamycin pathway in lentiviral vector transduction of hematopoietic stem cellsThe role of mTOR signaling in Alzheimer diseaseNitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosisS6K1 is a multifaceted regulator of Mdm2 that connects nutrient status and DNA damage responseThe Complex Roles of Mechanistic Target of Rapamycin in Adipocytes and Beyond.Novel quantitative autophagy analysis by organelle flow cytometry after cell sonication.mTOR Ser-2481 autophosphorylation monitors mTORC-specific catalytic activity and clarifies rapamycin mechanism of actionModerate Autophagy Inhibits Vascular Smooth Muscle Cell Senescence to Stabilize Progressed Atherosclerotic Plaque via the mTORC1/ULK1/ATG13 Signal Pathway.Clinical trials for rare lung diseases: lessons from lymphangioleiomyomatosis.HIV-1 enhances mTORC1 activity and repositions lysosomes to the periphery by co-opting Rag GTPases.Developments in Burkitt's lymphoma: novel cooperations in oncogenic MYC signaling.An mTOR anti-sense oligonucleotide decreases polycystic kidney disease in mice with a targeted mutation in Pkd2.Human immunodeficiency virus-1 inhibition of immunoamphisomes in dendritic cells impairs early innate and adaptive immune responses.TOR signaling never gets old: aging, longevity and TORC1 activity.Ligands for FKBP12 increase Ca2+ influx and protein synthesis to improve skeletal muscle function.Pharmacological regulators of autophagy and their link with modulators of lupus diseaseLow concentration of rapamycin inhibits hemangioma endothelial cell proliferation, migration, and vascular tumor formation in mice.Growing knowledge of the mTOR signaling network.GSK-3 modulates cellular responses to a broad spectrum of kinase inhibitorsCaloric restriction promotes the reserve of follicle pool in adult female rats by inhibiting the activation of mammalian target of rapamycin signaling.Coibamide A induces mTOR-independent autophagy and cell death in human glioblastoma cells.Synthetic lethality of combined glutaminase and Hsp90 inhibition in mTORC1-driven tumor cellsRegulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers.mTOR kinase: a possible pharmacological target in the management of chronic pain.Mammalian target of rapamycin signaling and autophagy: roles in lymphangioleiomyomatosis therapyUp-regulation of lysosomal TRPML1 channels is essential for lysosomal adaptation to nutrient starvation.Autophagy as a therapeutic target in cardiovascular disease.Release of human cytomegalovirus from latency by a KAP1/TRIM28 phosphorylation switchInteraction of mTOR and Erk1/2 signaling to regulate oligodendrocyte differentiation.Insulin-like growth factor I suppresses bone morphogenetic protein signaling in prostate cancer cells by activating mTOR signaling
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Rapamycin inhibits mTORC1, but not completely.
@en
Rapamycin inhibits mTORC1, but not completely.
@nl
type
label
Rapamycin inhibits mTORC1, but not completely.
@en
Rapamycin inhibits mTORC1, but not completely.
@nl
prefLabel
Rapamycin inhibits mTORC1, but not completely.
@en
Rapamycin inhibits mTORC1, but not completely.
@nl
P356
P1433
P1476
Rapamycin inhibits mTORC1, but not completely
@en
P2093
Carson C Thoreen
P304
P356
10.4161/AUTO.5.5.8504
P577
2009-07-22T00:00:00Z