Discovery of novel benzene 1,3-dicarboxylic acid inhibitors of bacterial MurD and MurE ligases by structure-based virtual screening approach.
about
Resistance to antibiotics targeted to the bacterial cell wallSpecificity Determinants for Lysine Incorporation in Staphylococcus aureus Peptidoglycan as Revealed by the Structure of a MurE Enzyme Ternary ComplexCrystallographic Study of Peptidoglycan Biosynthesis Enzyme MurD: Domain Movement RevisitedDual Inhibitor of MurD and MurE Ligases from Escherichia coli and Staphylococcus aureus.Virtual screening for potential inhibitors of homology modeled Leptospira interrogans MurD ligaseCombinatorially-generated library of 6-fluoroquinolone analogs as potential novel antitubercular agents: a chemometric and molecular modeling assessment.In silico identification of common putative drug targets in Leptospira interrogansSynthesis of ureidomuraymycidine derivatives for structure-activity relationship studies of muraymycins.Development of a one-pot assay for screening and identification of Mur pathway inhibitors in Mycobacterium tuberculosis.Functional and biochemical analysis of the Chlamydia trachomatis ligase MurE.Improved synthesis of capuramycin and its analogues.Multitarget ligands in antibacterial research: progress and opportunities.The biology of Mur ligases as an antibacterial target.Structure-Based Pharmacophores for Virtual Screening.Discovery of Cdc25A Lead Inhibitors with a Novel Chemotype by Virtual Screening: Application of Pharmacophore Modeling Based on a Training Set with a Limited Number of Unique Components.Furan-based benzene mono- and dicarboxylic acid derivatives as multiple inhibitors of the bacterial Mur ligases (MurC-MurF): experimental and computational characterization.Discovery of mono- and disubstituted 1H-pyrazolo[3,4]pyrimidines and 9H-purines as catalytic inhibitors of human DNA topoisomerase IIα.Molecular dynamics simulation and linear interaction energy study of D-Glu-based inhibitors of the MurD ligase.Cluster-based molecular docking study for in silico identification of novel 6-fluoroquinolones as potential inhibitors against Mycobacterium tuberculosis.Virtual screening for potential inhibitors of bacterial MurC and MurD ligases
P2860
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P2860
Discovery of novel benzene 1,3-dicarboxylic acid inhibitors of bacterial MurD and MurE ligases by structure-based virtual screening approach.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Discovery of novel benzene 1,3 ...... ed virtual screening approach.
@en
Discovery of novel benzene 1,3 ...... ed virtual screening approach.
@nl
type
label
Discovery of novel benzene 1,3 ...... ed virtual screening approach.
@en
Discovery of novel benzene 1,3 ...... ed virtual screening approach.
@nl
prefLabel
Discovery of novel benzene 1,3 ...... ed virtual screening approach.
@en
Discovery of novel benzene 1,3 ...... ed virtual screening approach.
@nl
P2093
P50
P1476
Discovery of novel benzene 1,3 ...... ed virtual screening approach.
@en
P2093
Andreja Kovac
Didier Blanot
Tom Solmajer
P304
P356
10.1016/J.BMCL.2009.03.141
P407
P577
2009-04-01T00:00:00Z