RGS4 inhibits Gq-mediated activation of mitogen-activated protein kinase and phosphoinositide synthesis.
about
Gq/11-mediated signaling and hypertrophy in mice with cardiac-specific transgenic expression of regulator of G-protein signaling 2RGS3 inhibits G protein-mediated signaling via translocation to the membrane and binding to Galpha11Cytoplasmic, nuclear, and golgi localization of RGS proteins. Evidence for N-terminal and RGS domain sequences as intracellular targeting motifsRGS-GAIP, a GTPase-activating protein for Galphai heterotrimeric G proteins, is located on clathrin-coated vesiclesRGS4 and RGS2 bind coatomer and inhibit COPI association with Golgi membranes and intracellular transportRGS2/G0S8 is a selective inhibitor of Gqalpha functionInteraction between RGS7 and polycystinA regulator of G protein signaling, RGS3, inhibits gonadotropin-releasing hormone (GnRH)-stimulated luteinizing hormone (LH) secretionPolarity exchange at the interface of regulators of G protein signaling with G protein alpha-subunitsRGS7 and RGS8 differentially accelerate G protein-mediated modulation of K+ currentsG beta 5.RGS7 inhibits G alpha q-mediated signaling via a direct protein-protein interactionExpression of GTPase-deficient Gialpha2 results in translocation of cytoplasmic RGS4 to the plasma membraneRGS2 blocks slow muscarinic inhibition of N-type Ca(2+) channels reconstituted in a human cell lineSrc is required for mechanical stretch-induced cardiomyocyte hypertrophy through angiotensin II type 1 receptor-dependent β-arrestin2 pathways.Non-canonical functions of RGS proteinsRegulator of G protein signaling Z1 (RGSZ1) interacts with Galpha i subunits and regulates Galpha i-mediated cell signaling.Alterations in metabotropic glutamate receptor 1α and regulator of G protein signaling 4 in the prefrontal cortex in schizophrenia.Hypoxic induction of the regulator of G-protein signalling 4 gene is mediated by the hypoxia-inducible factor pathway.Opioid-induced down-regulation of RGS4: role of ubiquitination and implications for receptor cross-talk.A Gsalpha mutant designed to inhibit receptor signaling through Gs.Adrenergic modulation of NMDA receptors in prefrontal cortex is differentially regulated by RGS proteins and spinophilinRGS4 overexpression in the rat dorsal striatum modulates mGluR5- and amphetamine-mediated behavior and signaling.R4 RGS proteins: regulation of G-protein signaling and beyond.Regulators of G protein signaling attenuate the G protein-mediated inhibition of N-type Ca channelsRegulation of psychostimulant-induced signaling and gene expression in the striatumRGS6, but not RGS4, is the dominant regulator of G protein signaling (RGS) modulator of the parasympathetic regulation of mouse heart rate.Negative regulation of alpha2-adrenergic receptor-mediated Gi signalling by a novel pathway.Second site suppressor mutations of a GTPase-deficient G-protein alpha-subunit. Selective inhibition of Gbeta gamma-mediated signaling.Post-cocaine changes in regulator of G-protein signaling (RGS) proteins in the dorsal striatum: Relevance for cocaine-seeking and protein kinase C-mediated phosphorylation.Cholinergic/glutamatergic co-transmission in striatal cholinergic interneurons: new mechanisms regulating striatal computation.Differential effects of melatonin and its downstream effector PKCalpha on subcellular localization of RGS proteins.Endogenous RGS protein action modulates mu-opioid signaling through Galphao. Effects on adenylyl cyclase, extracellular signal-regulated kinases, and intracellular calcium pathways.5-Hydroxytryptamine 4(a) receptor is coupled to the Galpha subunit of heterotrimeric G13 protein.Natriuretic peptides inhibit G protein activation. Mediation through cross-talk between cyclic GMP-dependent protein kinase and regulators of G protein-signaling proteins.RGS4 is arginylated and degraded by the N-end rule pathway in vitro.Regulators of G protein signaling (RGS) proteins constitutively activate Gbeta gamma-gated potassium channels.The regulator of G protein signaling RGS4 selectively enhances alpha 2A-adreoreceptor stimulation of the GTPase activity of Go1alpha and Gi2alpha.Unique isoform of Galpha -interacting protein (RGS-GAIP) selectively discriminates between two Go-mediated pathways that inhibit Ca2+ channels.Differences in regional and subcellular localization of G(q/11) and RGS4 protein levels in Alzheimer's disease: correlation with muscarinic M1 receptor binding parameters.Differential contribution of GTPase activation and effector antagonism to the inhibitory effect of RGS proteins on Gq-mediated signaling in vivo.
P2860
Q21134156-64E7C62B-7C18-413E-9227-407A2E48022EQ22008566-F8EF3561-04FA-480F-A96E-EB176B010CF6Q22254020-6EBF39F5-C8F7-4594-92B7-040AB4C8CD08Q24313026-1E56946B-9B0C-45C9-8946-2FDF3FFEA210Q24550714-F6F51DDE-523F-4E2E-94F6-D90799E52295Q24648296-6371AA34-2C9B-4136-B1B8-5F54B51225E6Q24653605-A447D863-EE00-46CF-8818-B6EB4B50F791Q24794799-CB6D4AC6-73B2-47A0-8A64-A8D458EF3713Q28139726-2BA53F87-1192-4857-B875-D6095703E8ADQ28139736-4A1F343A-F899-494A-B705-0C5ECDA8BD65Q28188095-4E83D1F3-D294-4E3F-94AC-F6035E1ECC5AQ28276163-3A337C68-9604-4EFF-B8B4-9494057A55A8Q28362831-6A1FF447-E4D9-4040-A513-EE4BAC840BC9Q31156054-0739ECFF-3DE9-47CB-B819-65BD116F8344Q33945560-B0949C69-FF20-4BEB-9701-6AB23FAE433CQ34154440-88443969-3B66-45C4-8D85-E106A965F8B3Q34384480-C6A8F0EE-2FB8-4A96-8DD3-16F62A84D1C7Q34412532-FFA97CF0-9B43-473F-9A0C-9AEB39E047C8Q34624142-7B005F35-087F-435F-8884-920853F503F6Q34817858-BFFCA0E5-7F79-45FE-9071-A6B3ED768718Q35722397-C3C38E04-E45C-4292-A5B7-FDAB103B850BQ35867186-D78EFE19-904B-458F-836E-4611188F84C4Q36301542-72165592-026D-42AE-824F-89681CDD6161Q36420546-FA7CAFC9-CA9B-46FE-A32F-159659326BC6Q37067582-D74A12EC-D18A-4FE7-8BD2-B48D74B4B8A5Q37511811-B7BE5003-2969-41DF-ADFB-B7F5B012C841Q38320365-1B34A617-A857-41D7-91DF-3F42CD2917F6Q38332220-C0B820ED-E8B2-48BB-898F-71CD94620E28Q38858218-65FF1A13-2FAC-44D0-BB17-A374DAE5614EQ39250067-19B5744D-6EA8-41FA-A2B3-FA2405D95B69Q40324169-B5F5F0F0-D129-439C-9C26-20FAF3A5C67BQ40678245-4A125381-2CDB-45C8-A362-33D278F0463BQ40741502-C3E85297-91DC-4754-803D-1E36E6BA4471Q41723060-7FF022CE-9120-4C27-BF66-CB8C487912ADQ41732590-39821657-4808-4322-B955-3817763A0C6DQ42463888-E76C8433-0AC9-430E-9AAE-B985EB186188Q42487898-18931EED-B624-40F6-B1CC-F749A1D22C38Q44149497-DF7CBAA3-FF6A-4008-9735-BCEA8C0AC15AQ44209559-93E81251-267F-4D74-BCA5-707F0DB5ECB8Q44664100-BD587E8C-1D24-4ACE-9DA2-1FCBCCD1825F
P2860
RGS4 inhibits Gq-mediated activation of mitogen-activated protein kinase and phosphoinositide synthesis.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
RGS4 inhibits Gq-mediated acti ...... nd phosphoinositide synthesis.
@en
RGS4 inhibits Gq-mediated acti ...... nd phosphoinositide synthesis.
@nl
type
label
RGS4 inhibits Gq-mediated acti ...... nd phosphoinositide synthesis.
@en
RGS4 inhibits Gq-mediated acti ...... nd phosphoinositide synthesis.
@nl
prefLabel
RGS4 inhibits Gq-mediated acti ...... nd phosphoinositide synthesis.
@en
RGS4 inhibits Gq-mediated acti ...... nd phosphoinositide synthesis.
@nl
P2093
P2860
P356
P1476
RGS4 inhibits Gq-mediated acti ...... nd phosphoinositide synthesis.
@en
P2093
P2860
P304
11924-11927
P356
10.1074/JBC.272.18.11924
P407
P577
1997-05-01T00:00:00Z