Features of ribosome-peptidyl-tRNA interactions essential for tryptophan induction of tna operon expression.
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RNA-based regulation of genes of tryptophan synthesis and degradation, in bacteriaStructural insight into nascent polypeptide chain-mediated translational stalling.Side-chain recognition and gating in the ribosome exit tunnel.Macrolide antibiotics allosterically predispose the ribosome for translation arrest.Recombineering reveals a diverse collection of ribosomal proteins L4 and L22 that confer resistance to macrolide antibiotics.Genetic identification of nascent peptides that induce ribosome stalling.rRNA mutations that inhibit transfer-messenger RNA activity on stalled ribosomes.Non-bulk-like solvent behavior in the ribosome exit tunnel.The N-terminus of GalE induces tmRNA activity in Escherichia coli.SecM-stalled ribosomes adopt an altered geometry at the peptidyl transferase center.The arginine attenuator peptide interferes with the ribosome peptidyl transferase center.The key function of a conserved and modified rRNA residue in the ribosomal response to the nascent peptide.The conformation of a nascent polypeptide inside the ribosome tunnel affects protein targeting and protein folding.Sequence selectivity of macrolide-induced translational attenuationRibosome pausing, arrest and rescue in bacteria and eukaryotes.Changes produced by bound tryptophan in the ribosome peptidyl transferase center in response to TnaC, a nascent leader peptideAn indigenous posttranscriptional modification in the ribosomal peptidyl transferase center confers resistance to an array of protein synthesis inhibitors.Picky nascent peptides do not talk to foreign ribosomes.Role of antibiotic ligand in nascent peptide-dependent ribosome stallingBirth, life and death of nascent polypeptide chains.Low fitness cost of the multidrug resistance gene cfr.Isolation of translating ribosomes containing peptidyl-tRNAs for functional and structural analysesRecognition of the regulatory nascent chain TnaC by the ribosomeRibosome recycling factor and release factor 3 action promotes TnaC-peptidyl-tRNA Dropoff and relieves ribosome stalling during tryptophan induction of tna operon expression in Escherichia coliRibosomal features essential for tna operon induction: tryptophan binding at the peptidyl transferase center.Crucial elements that maintain the interactions between the regulatory TnaC peptide and the ribosome exit tunnel responsible for Trp inhibition of ribosome function.Antibiotics and the ribosome.Mutational robustness of 16S ribosomal RNA, shown by experimental horizontal gene transfer in Escherichia coli.Arginine changes the conformation of the arginine attenuator peptide relative to the ribosome tunnelFrom ribosome to riboswitch: control of gene expression in bacteria by RNA structural rearrangements.Nascent peptides that block protein synthesis in bacteria.Conserved residues Asp16 and Pro24 of TnaC-tRNAPro participate in tryptophan induction of Tna operon expression.Mutations in the Escherichia coli ribosomal protein L22 selectively suppress the expression of a secreted bacterial virulence factor.Modulating the activity of the peptidyl transferase center of the ribosome.Electrostatics in the ribosomal tunnel modulate chain elongation rates.Regional discrimination and propagation of local rearrangements along the ribosomal exit tunnel.The ribosome: a metabolite-responsive transcription regulator.23S rRNA nucleotides in the peptidyl transferase center are essential for tryptophanase operon inductionThe plasticity of a translation arrest motif yields insights into nascent polypeptide recognition inside the ribosome tunnelMaintenance of Transcription-Translation Coupling by Elongation Factor P.
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P2860
Features of ribosome-peptidyl-tRNA interactions essential for tryptophan induction of tna operon expression.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Features of ribosome-peptidyl- ...... tion of tna operon expression.
@en
Features of ribosome-peptidyl- ...... tion of tna operon expression.
@nl
type
label
Features of ribosome-peptidyl- ...... tion of tna operon expression.
@en
Features of ribosome-peptidyl- ...... tion of tna operon expression.
@nl
prefLabel
Features of ribosome-peptidyl- ...... tion of tna operon expression.
@en
Features of ribosome-peptidyl- ...... tion of tna operon expression.
@nl
P2093
P1433
P1476
Features of ribosome-peptidyl- ...... tion of tna operon expression.
@en
P2093
Catherine Squires
Charles Yanofsky
Luis Rogelio Cruz-Vera
Soumitra Rajagopal
P304
P356
10.1016/J.MOLCEL.2005.06.013
P577
2005-08-01T00:00:00Z