Redox control of exocytosis: regulatory role of NADPH, thioredoxin, and glutaredoxin.
about
Silencing of cytosolic or mitochondrial isoforms of malic enzyme has no effect on glucose-stimulated insulin secretion from rodent isletsRole for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretionChronic suppression of acetyl-CoA carboxylase 1 in beta-cells impairs insulin secretion via inhibition of glucose rather than lipid metabolismMetabolomics applied to the pancreatic isletRegulation of ion channels by pyridine nucleotidesRedox homeostasis in pancreatic β cellsThe thioredoxin TRX-1 modulates the function of the insulin-like neuropeptide DAF-28 during dauer formation in Caenorhabditis elegansTransamination is required for {alpha}-ketoisocaproate but not leucine to stimulate insulin secretionThioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signalingFeasibility of pathways for transfer of acyl groups from mitochondria to the cytosol to form short chain acyl-CoAs in the pancreatic beta cellSpecificity in beta cell expression of L-3-hydroxyacyl-CoA dehydrogenase, short chain, and potential role in down-regulating insulin releaseGlutaredoxin-1 mediates NADPH-dependent stimulation of calcium-dependent insulin secretionMalic enzyme is present in mouse islets and modulates insulin secretionAMP-activated protein kinase (AMPK) mediates nutrient regulation of thioredoxin-interacting protein (TXNIP) in pancreatic beta-cellsSubplasmalemmal Ca(2+) measurements in mouse pancreatic beta cells support the existence of an amplifying effect of glucose on insulin secretionPlasma membrane potential oscillations in insulin secreting Ins-1 832/13 cells do not require glycolysis and are not initiated by fluctuations in mitochondrial bioenergetics.β-Cell failure in type 2 diabetes.Lack of TXNIP protects against mitochondria-mediated apoptosis but not against fatty acid-induced ER stress-mediated beta-cell death.DeSUMOylation Controls Insulin Exocytosis in Response to Metabolic Signals.Mitochondrial metabolism of pyruvate is essential for regulating glucose-stimulated insulin secretionSphingosine kinase 1-interacting protein is a novel regulator of glucose-stimulated insulin secretionDifferential expression of islet glutaredoxin 1 and 5 with high reactive oxygen species production in a mouse model of diabesityNNT reverse mode of operation mediates glucose control of mitochondrial NADPH and glutathione redox state in mouse pancreatic β-cells.Functional recovery of diabetic mouse hearts by glutaredoxin-1 gene therapy: role of Akt-FoxO-signaling network.The mitochondrial 2-oxoglutarate carrier is part of a metabolic pathway that mediates glucose- and glutamine-stimulated insulin secretion.Regulation of insulin secretion: role of mitochondrial signalling.Glucose sensing in the pancreatic beta cell: a computational systems analysis.Control of the intracellular redox state by glucose participates in the insulin secretion mechanismPyruvate dehydrogenase kinase 1 controls mitochondrial metabolism and insulin secretion in INS-1 832/13 clonal beta-cells.Compensatory responses to pyruvate carboxylase suppression in islet beta-cells. Preservation of glucose-stimulated insulin secretion.In vivo multiphoton NADH fluorescence reveals depth-dependent keratinocyte metabolism in human skin.Mice deficient in the respiratory chain gene Cox6a2 are protected against high-fat diet-induced obesity and insulin resistance.Cytosolic and mitochondrial malic enzyme isoforms differentially control insulin secretion.Cellular hypoxia of pancreatic beta-cells due to high levels of oxygen consumption for insulin secretion in vitro.Reduced cytochrome C is an essential regulator of sustained insulin secretion by pancreatic isletsInvestigating the roles of mitochondrial and cytosolic malic enzyme in insulin secretion.A role for cytosolic isocitrate dehydrogenase as a negative regulator of glucose signaling for insulin secretion in pancreatic ß-cells.Modulation of glutaredoxin in the lung and sputum of cigarette smokers and chronic obstructive pulmonary diseaseMechanisms of glucose sensing in the pancreatic β-cell: A computational systems-based analysis.The level of menadione redox-cycling in pancreatic β-cells is proportional to the glucose concentration: role of NADH and consequences for insulin secretion.
P2860
Q24649735-5BA5EF43-16FB-45A4-B105-367BEFC06B37Q24649771-B5B6617C-AF4F-4E8D-AD9F-F4DB441CA04BQ24653884-26EDD8CA-C999-4FCD-BED2-4FF05FDC4187Q26824852-833BAB81-00C5-4DBE-82A9-A723D94F4582Q26827261-45E56104-D9EF-4490-8242-43DB970BD8A9Q27021930-9094B5EF-FE8E-4EAC-9231-911F835730E2Q27437622-5F4ADCEA-1CF5-416A-85AA-2030C481BC76Q28291461-D50A5393-134D-4723-99C1-C5FBE06A0550Q28389739-A6899E92-22F3-4C9E-A54B-B5B2FAEA442CQ28565418-451CE4B0-01F6-463F-B364-9C2816592A73Q28566284-FC64B9F8-E0AA-4723-B14E-54223A792534Q28577614-E3D3B280-A1BC-433B-8AD3-A95583ED7C9EQ28591279-C969963E-4C62-4A10-82C0-A1282DA0B3A0Q28741436-898E6BA2-0FDA-42A6-9831-CAED4970C655Q29036821-32673FDE-8F7A-4296-B910-43A833728187Q30513973-D77E9915-32B6-4354-8764-BB2D9895A64DQ33588325-7DE4C8DF-B6EB-418C-8716-A20EAA23B58AQ33604522-3574ECFB-9AB6-4935-8F8B-73077073F492Q33649512-06EF7BF8-DA61-4E25-9B15-C29C4B75917CQ33676670-F0AC79B8-2C27-4499-9DAB-A478366958CDQ33677977-6EF97BCA-F8DB-428E-9677-D1BA52EBCAF2Q33724707-5EBDA1BE-F34E-4C91-B9F1-D0A1E1804B1FQ33726651-EC75E85A-8866-4624-A90F-E74669DE7153Q33778090-4A0D6729-27AE-4DF1-B0E8-3B6BB4F5B25AQ33883478-62D87D55-30B8-415B-AC91-A3F3E75F27C0Q33914248-FE7E2A16-9617-421E-AEA1-FF5E24C735EDQ33961250-96D8198C-679C-43C1-B411-E399F74DD5EDQ34016498-3B90AFAB-6082-4BA8-98D6-A213DF1C8752Q34111818-29687B3D-0D40-4274-9B64-8DCF09C7C59BQ34532972-792B5354-8D95-4B3F-8B59-60D81AADC685Q34554535-84B698EA-3B8D-40B8-8721-46B8E98F6573Q34608360-22EC03F4-8DD2-42EC-848C-7984080F32BDQ34653077-6A7EEA25-0F8C-4D56-9E83-73E4F6EED8BDQ34752423-5B04A6E4-9D4E-4A5A-8483-61CEE8312712Q34978857-153F72CD-3FE7-4EC4-82A5-F2EC9806FDF6Q34979995-BBD6A569-EC00-4832-9C3A-8173A7125C45Q35018731-E673DAE7-E1E2-4CC5-A830-FC52DCD08E7DQ35125384-29B24395-DEF5-4934-9F5E-1BB764FD6D69Q35558863-8FF68507-8D89-48C2-8861-446066716212Q35675195-AD8C8EA1-9164-42F8-8685-66301ABDA083
P2860
Redox control of exocytosis: regulatory role of NADPH, thioredoxin, and glutaredoxin.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Redox control of exocytosis: regulatory role of NADPH, thioredoxin, and glutaredoxin.
@en
Redox control of exocytosis: regulatory role of NADPH, thioredoxin, and glutaredoxin.
@nl
type
label
Redox control of exocytosis: regulatory role of NADPH, thioredoxin, and glutaredoxin.
@en
Redox control of exocytosis: regulatory role of NADPH, thioredoxin, and glutaredoxin.
@nl
prefLabel
Redox control of exocytosis: regulatory role of NADPH, thioredoxin, and glutaredoxin.
@en
Redox control of exocytosis: regulatory role of NADPH, thioredoxin, and glutaredoxin.
@nl
P2093
P1433
P1476
Redox control of exocytosis: regulatory role of NADPH, thioredoxin, and glutaredoxin.
@en
P2093
Erik Renström
Frans C Schuit
Katsura Tsukamoto
Peter in 't Veld
Roel Quintens
Rosita Ivarsson
Sandra Dejonghe
P304
P356
10.2337/DIABETES.54.7.2132
P407
P577
2005-07-01T00:00:00Z