Gain-of-function profilin 1 mutations linked to familial amyotrophic lateral sclerosis cause seed-dependent intracellular TDP-43 aggregation.

Gain-of-function profilin 1 mutations linked to familial amyotrophic lateral sclerosis cause seed-dependent intracellular TDP-43 aggregation.

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http://www.wikidata.org/entity/Q46591159
Intrinsic disorder in proteins involved in amyotrophic lateral sclerosis.Protein Quality Control and the Amyotrophic Lateral Sclerosis/Frontotemporal Dementia ContinuumProfilin1 biology and its mutation, actin(g) in disease.TDP-43 and Cytoskeletal Proteins in ALS.Familial Amyotrophic Lateral Sclerosis-linked Mutations in Profilin 1 Exacerbate TDP-43-induced Degeneration in the Retina of Drosophila melanogaster through an Increase in the Cytoplasmic Localization of TDP-43.Profilin 1 mutants form aggregates that induce accumulation of prion-like TDP-43BDNF/trkB Induction of Calcium Transients through Cav2.2 Calcium Channels in Motoneurons Corresponds to F-actin Assembly and Growth Cone Formation on β2-Chain Laminin (221).Molecular mechanisms of the co-deposition of multiple pathological proteins in neurodegenerative diseases.Mutant Profilin1 transgenic mice recapitulate cardinal features of motor neuron disease.Progranulin regulates lysosomal function and biogenesis through acidification of lysosomes.A Drosophila model of ALS reveals a partial loss of function of causative human PFN1 mutants.Autophagy as a common pathway in amyotrophic lateral sclerosis.
P2860

Gain-of-function profilin 1 mutations linked to familial amyotrophic lateral sclerosis cause seed-dependent intracellular TDP-43 aggregation.

Item
http://www.wikidata.org/entity/Q46591159
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh-hant
name
Gain-of-function profilin 1 mu ...... racellular TDP-43 aggregation.
@en
Gain-of-function profilin 1 mu ...... racellular TDP-43 aggregation.
@nl
type
label
Gain-of-function profilin 1 mu ...... racellular TDP-43 aggregation.
@en
Gain-of-function profilin 1 mu ...... racellular TDP-43 aggregation.
@nl
prefLabel
Gain-of-function profilin 1 mu ...... racellular TDP-43 aggregation.
@en
Gain-of-function profilin 1 mu ...... racellular TDP-43 aggregation.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P921
P356
P1433
P1476
Gain-of-function profilin 1 mu ...... racellular TDP-43 aggregation.
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P921